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Faculty and Staff Publications

2013

Xue, F.; Stoica, B. A.; Hanscom, M.; Kabadi, S. V.; FADEN A.I.  “Positive Allosteric Modulators (PAMs) of Metabotropic Glutamate Receptor 5 (mGluR5) Attenuate Microglial Activation” CNS & Neurol. Disord. Drug Targets 2013, in press.

Lakkaraju, S.; Xue, F.; Faden, A.; MacKerell, A.  Estimation of ligand efficacies of metabotropic glutamate receptors from conformational forces obtained from molecular dynamics simulations.  Journal of Chemical Information and Modeling.  Accepted on May 2013.  DOI: 10.1021/ci400160x

Wu J, Renn CL, Faden AI, Dorsey SG. TrkB.T1 contributes to neuropathic pain following spinal cord injury through regulation of cell cycle pathways. Journal of Neuroscience, 2013 IN PRESS.

Wu J, Raver C, Piao C, Keller A, Faden AI.  Cell Cycle Activation Contributes to Increased Neuronal Activity in the Posterior Thalamic Nucleus and Associated Chronic Hyperesthesia after Rat Spinal Cord Contusion.  Neurotherapeutics. 2013 Jun 18. [Epub ahead of print]

Zhao Z, Faden AI, Loane DJ, Lipinski M, Sabirzhanov S, Stoica B.  Neuroprotective effects of geranylgeranylacetone in experimental traumatic brain injury.  Journal of Cerebral Blood Flow & Metabolism (2013), IN PRESS.

Andrews PL, Scalea T, Habashi NM.  What’s in a name?  Mechanical ventilation is at the mercy of the operator.  Journal of Trauma.  74:1377, 2013.

Harris DG, Drucker CB, Brenner ML, Narayan M, Sarkar R, Scalea TM and Crawford RS.  Patterns and management of blunt iliac arterial injuries.  Journal of Vascular Surgery.  57(5), May 2013.

Balan I, Saladino A, Aarabi B, Castellani R, Wade C, Stein DM, Eisenberg H, Chen HH, Fiskum G.  Cellular alterations in human traumatic brain injury: Changes in mitochondrial morphology reflect regional levels of injury severity.  J Neurotrauma. 2013;30(5):367-381.

Stein DM, Jessie EM, Crane S, Kufera JA, Timmons T, Rodriguez CJ, Menaker J, Scalea TM.  Hyperacute adrenal insufficiency (HAI) after hemorrhagic shock exists and is associated with poor outcomes.  J Trauma Acute Care Surg. 2013;74(2):363-70

Stein DM, Brenner, M, Hu, PF, Yang S, Hall EC, Stansbury LG, Menaker J, Scalea TM. Timing of intracranial hypertension following severe traumatic brain injury. Neurocrit Care. 2013;18(3):332-340.

Galvagno SM, Hong CM, Lissauer ME, Baker AK, Murthi SB, Herr DL, Stein DM. Practical considerations for the dosing and adjustment of continuous renal replacement therapy in the intensive care unit. J Critical Care. 2013; doi:pii: S0883-9441(13)00143-3.10.1016/j.jcrc.2013.05.018 [Epub ahead of print]

Sheth KN, Stein DM, Aarabi B, Hu PF, Kufera JA, Scalea TM, Hanley DF.  Intracranial pressure dose and outcome in traumatic brain injury.  Neurocritical Care.  2013;18:26-32.

Owens K, Park JH, Kristian T.  Utilizing commercial microwave for rapid and effective immunostaining.  J Neurosci Methods. 2013 Jul 12;219(1):20-26. doi: 10.1016/j.jneumeth.2013.07.002. [Epub ahead of print]

Kristian T, Hu B.  Guidelines for Using Mouse Global Cerebral Ischemia Models.  Translational Stroke Research June 2013, Volume 4,  Issue 3, pp 343-350

Huffines M, Johnson KL, Smitz Naranjo LL, Lissauer ME, Fishel MAM, Howes SM, Pannullo D, Ralls M, Smith R. Improving Family Satisfaction and Participation in Decision Making in a Surgical ICU: a Multidisciplinary Collaborative Quality Improvement Project. Critical Care Nurse, Accepted for publication January 30, 2013

Kashani K, Al-Khafaji A, Ardiles T, Artigas A, Bagshaw SM, Bell M, Bihorac A, Birkhahn R, Cely CM, Chawla LS, Davison DL, Feldkamp T, Forni LG, Gong MN, Gunnerson KJ, Haase M, Hackett J, Honore PM, Hoste EAJ, Joannes-Boyau O, Joannidis M, Kim P, Koyner JL, Laskowitz DT, Lissauer ME, Marx G, McCullough PA, Mullaney S, Ostermann M, Rimmele T, Shapiro NI, Shaw AD, Shi J, Sprague AM, Vincent JL, Vinsonneau C, Wagner L, Walker MG, Wilkerson RG, Zacharowski K, Kellum JA. Discovery and Validation of Cell Cycle Arrest Biomarkers in Human Acute Kidney Injury. Critical Care 2013; 17:R25

Lissauer ME, Diaz JJ, Narayan M, Shah PK, Hanna NN. Surgical Intensive Care Unit Variables Predict Subsequent Readmission. American Surgeon. 2013; 79(6):583-588

Dubose JJ, Lissauer M, Maung AA, Piper GL, O’Callaghan TA, Luo-Owen X, Inabi K, Okoye O, Shestopalov A, Fielder WD, Ferrada P, Wilson A, Channel J, Moore FO, Paul DB, Johnson SB. Pneumatosis Intestinalis Predictive Evaluation Study (PIPES): A Multicenter Epidemiologic Study of the Eastern Association for the Surgery of Trauma. Journal of Trauma and Acute Care Surgery. 2013; 75(1):15-23.

Salah Eldin W, Hirshon JM, Smith GS, Kamal AA, Abou-El-Fetouh A, El-Setouhy M. Health-related quality of life after serious occupational injury in Egyptian workers: a cross-sectional study. BMJ Open. 2012;2(6).

Rockett IR, Regier MD, Kapusta ND, Coben JH, Miller TR, Hanzlick RL, Todd KH, Sattin RW, Kennedy LW, Kleinig J, Smith GS. Leading causes of unintentional and intentional injury mortality: United States, 2000-2009. Am J Public Health. 2012 Nov;102(11):e84-92.

Zhu M, Zhao S, Coben JH, Smith GS. Why more male pedestrians die in vehicle-pedestrian collisions than female pedestrians: a decompositional analysis. Inj Prev. 2012 Nov 29;

Dale Y, Dutton R, Hu P, Chang Y, Brown C, Chen H, Grissom T, Kufera J, Scalea T.  Effect of Video Laryngoscopy on Trauma Patient Survival: A Randomized Controlled Trial. J Trauma Acute Care Surg. 2013 Jul 2. [Epub ahead of print] PMID: 23823612

Brenner M, Stein D, Hu P, Kufera J, Wooford M, Scalea T. Association Between Early Hyperoxia and Worse Outcomes After Traumatic Brain Injury. Arch Surg. 2012 Nov 1;147(11):1042-6 PMID:22801994

Polster, B.M. (2013) AIF, reactive oxygen species, and neurodegeneration:  a “complex” problem.  Neurochem Int 62: 695-702. (Part of a special issue entitled "Oxidative Stress and Neurodegeneration")

Laird, M.D., Clerc, P., Polster, B.M., and Fiskum, G. (2013) Augmentation of Normal and Glutamate-Impaired Neuronal Respiratory Capacity by Exogenous Alternative Biofuels.  Translational Stroke Research (in press)

Stauffer C, Josiah AF, Fortes M, Menaker J, Cole JW. Lemierre Syndrome Secondary to Community-Acquired Methicillin-Resistant Staphylococcus Aureus Infection Associated with Cavernous Sinus Thromboses. J Emerg Med. 2013;44:e177-e182.

Boswell K, Menaker J. An update on spinal cord injury: Epidemiology, diagnosis and treatment for the emergency physician. Trauma Reports Jan/Feb 2013;14(1):1-12.

Stein DM, Jessie E, Crane S, Kufera J, Rodriguez C, Menaker J, Timmons T, Scalea TM. Hyperacute adrenal insufficiency (HAI) after hemorrhagic shock exists and is associated with poor outcomes. J Trauma Acute Care Surg 2013 Feb;74(2):363-70.

Holmes JF, Lillis K, Monroe D, Borgialli D, Kerrey BT, Mahajan P, Adelgais K, Ellison AM, Yen K, Atabaki S, Menaker J, Bonsu B, Quayle KS, Garcia M, Rogers A, Blumberg S, Lee L, Tunik M, Kooistra J, Kwok M, Cook LJ, Dean JM, Sokolove PE, Wisner DH, Ehrlich P, Cooper A, Dayan PS, Wootton-Gorges S, Kuppermann N; Pediatric Emergency Care Applied Research Network (PECARN). Identifying Children at Very Low Risk of Clinically Important Blunt Abdominal Injuries. Ann Emerg Med. 2013 Jan 29. [Epub ahead of print]

Inaba K, Menaker J, Branco BC, Gooch J, Okoye OT, Herrold J, Scalea TM, DuBose J, Demetriades D.  A prospective multicenter comparison of levetiracetam versus phenytoin for early post-traumatic seizure prophylaxis. J Trauma Acute Care Surg. 2013;74:766-73.

Bradley M, Okoye O, Dubose J, Inaba K, Demetriades D, Scalea T, O'Connor J, Menaker J, Morales C, Shiflett T, Brown C. Risk factors for post-traumatic pneumonia in patients with retained haemothorax: Results of a prospective, observational AAST study. Injury. 2013 Feb 19. [Epub ahead of print]

Jain A, Menaker J. Ultrasound for Trauma. Trauma Reports. May/June 2013;14(3):1-13.

Scalea JR, Menaker J, Meeks K, Kramer ME, Kufera JA, Auman KM, Cooper M, Bartlett ST, Scalea TM.  Trauma Patients with Prior Organ Transplants - Outcomes are Better than Expected: A Retrospective Analysis. J Trauma Acute Care Surg. 2013;74:1498-503.

Menaker J, Kufera, JA, Glaser J, Stein DM, Scalea TM. Admission ASIA Motor Score Predicting The Need For Tracheostomy After Cervical Spinal Cord Injury.  J Trauma Acute Care Surg (Accepted) 

Roman P, Battafarano, RJ, Grigore AM. Anesthesia for Tracheal Reconstruction and Transplantation. Current Opinion in Anesthesiology. 2013 Feb; 26(1):1-5.

Deshpande SP, Grigore AM. Robotic Surgery is the Preferred Technique for CABG Surgery.  Journal of Cardiothoracic and Vascular Anesthesia. 2013;27(4):602-605.

Odonkor P, Grigore A. Ischemic heart disease  Med Clin N AM. 2013; 97(6).

Fitzpatrick M, Alexander HR, Deshpande SP, McCormick B, Martz DG, Jr, Grigore, AM. Use of Partial Veno-Venous Cardiopulmonary Bypass in Percutaneous Hepatic Perfusion for Patients with Diffuse, Isolated Liver Metastases: A Case Series Journal of Cardiothoracic and Vascular Anesthesia. J Cardiothorac Vasc Anesth. (In press)

2012 

Clerc, P., Carey, G.B., Mehrabian, Z., Wei, M., Hwang, H., Girnun, G.D., Chen, H., Martin, SS., Polster, B.M. (2012) Rapid Detection of an ABT-737-sensitive Primed for Death State in Cells Using Microplate-based Respirometry. PLoS ONE 2012;7(8):e42487. Epub 2012 Aug 3. PMID: 22880001.

Stein DM, Hu P, Chen H, Stansbury LG, Yang S, Scalea TM. Computational "gene-mapping" to analyze continuous automated physiologic monitoring data in neuro-trauma intensive care. J Trauma Acute Care Surg. 2012 Aug;73(2):419-25. PMID: 22846949.

Kabadi SV, Stoica BA, Byrnes, KR, Hanscom M, Loane DJ, FADEN AI. Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma. J Cereb Blood Flow Metab. 2012 Jan;32(1):137-49. doi: 10.1038/jcbfm.2011.117. Epub 2011 Aug 10. PMID: 21829212.

Gupta R, Jovin T, Nguyen T, Gandhi D, Wisco D, Miller B, Horev A, Tayla A, Ludwig B, Hussian M, Terry J, Ludwig B, Belagaje SR, Cronin C, Tian M, Anderson AM, Frankel M, Sheth KN, Nogueira RG. Higher Volumes Endovascular Stroke Centers Have Decreased Time to Treatment. J Neurointerv Surg Epub ahead of print, 2012. PMID: 22581925.

Stein DM, Scalea TM. Capillary leak syndrome in trauma: What is it and what are its consequences? Adv Surg. 2012; 46:237-53. PMID: 22873043.

Kahn M, DuBose JJ. Improving Trauma Care in the ICU: Best Practices, Quality Improvement Initiatives, and Organization. Surg Clin North Am. 2012 Aug; 92(4): 893-901. Epub 2012 May 23. PMID: 22850153.

Sheth KN, Drogan O, Manno E, Geocadin RG, Ziai WC. Neuro-Critical Care Education During Neurology Residency: AAN Survey of US Program Directors. Neurology. 78(22): 1793-6, 2012. PMID: 22573636.

Loane DJ, Stoica BA, FADEN AI. Metabotropic glutamate receptor-mediated signaling in neuroglia. WIREs Membrane Transport and Signaling WIREs 2012, 1:136–150. PMID: 22662309.

Sheth KN, Shah N, Morovati T, Hermann LD, Cronin CA. Intravenous rt-PA is not Associated with Increased Risk of Hemorrhage in Patients with Intracranial Aneurysms. Neurocrit Care. 2012 Jul 3. [Epub ahead of print]. PMID: 22752394.

Diamantidis C, Zuckerman M, Fink W, Hu P, Yang S, Fink JC. Usability of a chronic kidney disease educational Web site targeted to patients and their family members. Clinical Journal of the American Society of Nephrology 2012 Jul 12 In Press. PMID 22798537.

Markov NP, DuBose JJ, Scott D, Propper BW, Clouse WD, Thompson B, Blackbourne LH, Rasmussen TE. Anatomic distribution and mortality of arterial injury in the wars in Afghanistan and Iraq with comparison to a civilian benchmark. J Vasc Surg. 2012 Jul 12. [Epub ahead of print]. PMID: 22795520.

Frankel HL, Butler KL, Cuschieri J, Friese RS, Huynh T, Mohr AM, Schinco MA, Napolitano LM, Britt LD, Coimbra R, Croce MA, Davis JW, Jurkovich GJ, Moore EE, Morris JA, Peitzman AB, Pruitt BA, Rozycki GS, Scalea TM, Meredith JW. The role and value of surgical critical care, an essential component of Acute Care Surgery, in the affordable care act: a report from the Critical Care Committee and Board of Managers of the American Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2012 Jul;73(1):20-26. PMID: 22743368.

Perez-Pinzon MA, Stetler RA, Fiskum G. Novel mitochondrial targets for neuroprotection. Journal of Cerebral Blood Flow & Metabolism. J Cereb Blood Flow Metab. 2012 Jul;32(7):1362-76. PMID:22453628.

Rasmussen TE, DuBose JJ, Asensio JA, Feliciano DV, Fox CJ, Nunez TC, Sise MJ; the Military Liaison Committee of the American Association for the Surgery of Trauma. Tourniquets, vascular shunts and endovascular technologies: Esoteric or essential? A report from the 2011 AAST Military Liaison Panel. J Trauma Acute Care Surg. 2012 Jul;73(1):282-285. PMID: 22743396.

Martin MJ, DuBose JJ, Rodriguez C, Dorlac WC, Beilman GJ, Rasmussen TE, Jenkins DH, Holcomb JB, Pruitt BA. “One front and one battle”: Civilian professional medical support of military surgeons. J Am Coll Surg. 2012 Jun 7. [Epub ahead of print]. PMID: 22683071.

Brenner M, Hu PF, Aarabi B, Sheth K, Scalea TM. Traditional systolic blood pressure targets underestimate hypotension-induced secondary brain injury. J Trauma Acute Care Surg. 2012 May;72(5):1135-9. PMID: 22673237.

Murthi S, Hess J, Hess A, Stansbury L, Scalea T. Focused rapid echocardiographic evaluation versus vascular catheter-based assessment of cardiac output and function in critically ill trauma patients. J Trauma Acute Care Surg. 2012 May;72(5):1158-64. PMID: 22673240.

Woodford M, Mackenzie C, DuBose J, Hu P, Kufera J, Hu E, Dutton R, Scalea T. Continuously Recorded SPO2 and Pulse Rate During Pre-hospital Transport Outperform Initial Measurement in Prediction of Mortality after Trauma. J Trauma Acute Care Surg. 2012 Apr;72(4):1006-11. PMID: 22491618.

Woodford MR, Mackenzie CF, DuBose J, Hu P, Kufera J, Hu EZ, Dutton RP, Scalea TM. Continuously recorded SpO2 and heart rate during pre-hospital transport outperform initial measurement in prediction of mortality after trauma. J Trauma Acute Care Surg. 2012 Apr;72(4):1006-11. PMID: 22491618.

O’Connor J, Chi A, Joshi M, DuBose J, Scalea T. Post-traumatic empyema: Etiology, surgery and outcome in 125 consecutive patients. Injury. 2012 Apr 23. [Epub ahead of print]. PMID: 22534461.

Woodford MR, Mackenzie CF, Dubose J, Hu P, Kufera J, Hu EZ, Dutton RP, Scalea TM. Continuously recorded oxygen saturation and heart rate during prehospital transport outperform initial measurement in prediction of mortality after trauma. J Trauma Acute Care Surg. 2012 Apr;72(4):1006-12. PMID: 22491618.

Scalea TM, DuBose JJ, Moore EE, West M, Moore FA, McIntyre R, Cocanour C, Davis J, Ochsner MG, Feliciano D. Western Trauma Association Critical Decisions in Trauma Management of the mangled extremity. J Trauma Acute Care Surg. 2012 Jan;72(1):86-93. PMID: 22310120.

McCranor BJ, Bozym RA, Vitolo MI, Fierke CA, Bambrick L, Polster BM, Fiskum G, Thompson RB. Quantitative imaging of mitochondrial and cytosolic free zinc levels in an in vitro model of ischemia/reperfusion. J. Bioenerg Biomembr. 2012 Apr;44(2):253-63. Epub 2012 Mar 20. PMID: 22430627.

DuBose JJ, Inaba K, Okoye O, Branco B, Barmparas G, Lyam L, Teixeira PG, Belzberg H, Demetriades D. Discrepancies between capillary glucose measurements and traditional laboratory assessments in both shock and non-shock states after trauma. J Surg Res. 2012 Apr 22 [Epub ahead of print]. PMID: 22626561.

Woodford MR, Mackenzie CF, DuBose J, Hu P, Kufera J, Hu EZ, Dutton RP, Scalea TM. Continuously recorded oxygen saturatin and heart rate during prehospital transport outperform initial measurement in prediction of mortality after trauma. J Trauma Acute Care Surg. 2012 Apr;72(4):1006-11. PMID: 22491618.

O’Connor JV, Chi A, Joshi M, DuBose J, Scalea TM. Post-traumatic empyema: Aetiology, surgery and outcome in 125 consecutive patients. Injury. 2012 Apr 23. [Epub ahead of print]. PMID: 22534461.

Onken M, Berger S, Kristian T. Simple model of forebrain ischemia in mouse. J Neurosci Methods. 2012 Mar 15;204(2):254-61. PMID: 22146544.

Kabadi SV, Stoica BA, Loane DJ, Byrnes KR, Hanscom M, Cabatbat RM, Tan MT, FADEN AI. Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury. J Neurotrauma. 2012 Mar 20;29(5):813-27. Epub 2012 Jan 13. PMID: 21895533.

Stein DM, Lindell AL, Murdock KR, Kufera JA, Menaker J, Bochicchio G, Aarabi B, Scalea TM. Use of Serum Biomarkers to Predict Cerebral Hypoxia Following Severe Traumatic Brain Injury. J Neurotrauma. 2012 Apr 10;29(6):1140-9. Epub 2012 Mar 29. PMID: 22360297.

Wehman B, Grigore AM, Griffith B, Bonatti J. Robotic Totally Endoscopic Coronary Artery Bypass Grafting for Spontaneous Coronary Artery Dissection. Int J Med Robot. 2012 Jun;8(2):166-8. doi: 10.1002/rcs.437. Epub 2012 Mar 7. PMID: 22396184.

Inaba K, Branco BC, Menaker J, Scalea TM, Crane S, DuBose JJ, Tung J, Reddy S, Demetriades D. Evaluation of multidetector computed tomography for penetrating neck injury: A prospective multicenter study. J Trauma Acute Care Surg. 2012 Mar;72(3):576-83; discussion 583-4; quiz 803-4. PMID: 22491539.

DuBose, J, Inaba K, Demetriades D, Scalea TM, O'Connor J, Menaker J, Morales C, Konstantinidis A, Stein DM, Lindell AL, Murdock KR, Kufera JA, Menaker J, Bochicchio G, Aarabi B, Scalea TM. J Neurotrauma. 2012 Apr 10;29(6):1140-9. Epub 2012 Mar 29. PMID: 22360297.

Piao CS, Loane DJ, Stoica BA, Li S, Hanscom M, Cabatbat R, Blomgren K, Faden AI. Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury. Neurobiol Dis. 2012 Jun;46(3):745-58. Epub 2012 Mar 9. PMID: 22426396.

Stein DM, Lindell AL, Murdock KR, Kufera JA, Menaker J, Scalea TM. Use of Serum Biomarkers to Predict Secondary Insults Following Severe Traumatic Brain Injury. Shock. 2012 Jun;37(6):563-8. PMID: 22552017.

Byrnes KR, Loane DJ, Stoica BA, Zhang J, Faden AI. Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury. J Neuroinflammation. 2012 Feb 28; 9:43. PMID: 22373400.

Markandaya M, Stein DM, Menaker J. Acute Treatment Options for Spinal Cord Injury. Curr Treat Options Neurol. 2012 Feb 3. [Epub ahead of print] PMID: 22302639.

Rabinowitz RP, Tabatabai A, Stein DM, Scalea TM.  Infectious complications in GSW’s through the gastrointestinal tract into the spine.  Injury. 2012 Feb. [Epub ahead of print].  PMID: 22306933. 

Sheth SS, Sheth KN.  Treatment of Neurocritical Care Emergencies in Pregnancy.  Curr Treat Options Neurol. 2012 Feb. [Epub ahead of print].  PMID: 22298283. 

Nogueira RG, Ferreira R, Grant E, Koroshetz WJ, Gonzalez RG, Sheth KN.  Restricted Diffusion in Spinal Cord Infarction Demonstrated by MR Line-Scan Diffusion Imaging.  Stroke. 2012 Feb;43(2):532-5. Epub 2011 Oct 27.  PMID: 22033988. 

Odonkor P, Stansbury LG, Gammie JS, Rock P, Fitzpatrick M, Grigore AM. Anesthetic Management of Patients Undergoing Aortic Valve Bypass (Apicoaortic Conduit) Surgery. Journal of Cardiothoracic and Vascular Anesthesia 2012 Feb;26(1):148-60. Epub 2011 Jul 2. PMID: 21724415.

*Sheth KN, *Yoo AJ, Kimberly WT, Chaudhry ZA, Elm JJ, Jacobson S, Davis SM, Donnan GA, Albers GW, Stern BJ, Gonzalez RG.  Validating Imaging Biomarkers of Cerebral Edema in Patients with Severe Ischemic Stroke.   J Stroke Cerebrovasc Dis. 2012 Feb 8. [Epub ahead of print]  PMID: 22325573. 

Michaels B, Csank G, Ryb G, Eko F, Rubin A. Prospective Randomized Comparison of OnabotulinumtoxinA (Botox) and AbobotulinumtoxinA (Dysport) in the Treatment of Forehead, Glabella and Periorbital Wrinkles. Aesthetic Surgery Journal. 2012 Jan 1; 32(1):96-102. PMID: 22231417.

Hinson HE, Sheth KN. Manifestations of the Hyperadrenergic State after Acute Brain Injury. Curr Opin Crit Care Epub ahead of print, 2012. PMID: 22322258.

Zhuo, J., Xu, S., Porter, J., Mullins, R.J., Simon, J.Z., Fiskum, G., and Gullapalli, R.P., Diffusion kurtosis as an in vivo imaging marker for reactive astrogliosis in traumatic brain injury. Neuroimage. 2012 Jan; 59(1):467-77. Epub 2011 Jul 30.  (PMID: 21835250). 

Regenold, W.T., Regenold, W., Pratt, M., Nekkalapu, S., Paul, S.S., Kristian, T., and Fiskum, G., Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling. J Psychiatr Res. 2012 Jan;46(1):95-104. Epub 2011 Oct 22.   (PMID 22018957). 

DuBose, J, Inaba K, Demetriades D, Scalea TM, O'Connor J, Menaker J, Morales C, Konstantinidis A, Shiflett A, Copwood B, the AAST Retained Hemothorax Study Group. Management of post-traumatic retained hemothorax: A prospective, observational, multicenter AAST study. J Trauma. 2012 Jan; 72(1):316-317. No abstract available. PMID: 22310147.

Rabin J, Chi A, Neschis DG, Griffith BP, Scalea TM. Blunt aortic injury in a patient with prior coronary artery bypass surgery. Ann Thorac Surg. 2012 Jan;93(1):294-6. PMID: 22186449.

2011 

Tuma MA, Stansbury LG, Stein DM, McQuillan KA, Scalea TM.  Induced hypothermia after cardiac arrest in trauma patients: a case series.  J Trauma. 2011 Dec;71(6):1524-7.PMID: 22182863 

Greco, T., Shafer, J., and Fiskum, G., Sulforaphane inhibits mitochondrial permeability transition and oxidative stress. Free Radic Biol Med. 2011 Dec; 51(12):2164-71. Epub 2011 Sep 21 (PMID: 21986339) 

Kahraman S, Bambrick LL, Fiskum G., Effects of FK506 and cyclosporin A on calcium ionophore-induced mitochondrial depolarization and cytosolic calcium in astrocytes and neurons. J Neurosci Res. 2011 Dec; 89(12):1973-8. doi: 10.1002/jnr.22709. Epub 2011 Jul 11.  PMID: 21748780, PMCID: PMC3191300 

Wang, H., Sreenevasan, U., Hu, H., Saladino, A., Polster, B.M., Lund L.M., Gong D.W., Stanley W.C., and Sztalryd, C. Perilipin 5, lipid droplet associated protein provides physical and metabolic linkage to mitochondria.  J Lipid Res. 2011 Dec; 52(12):2159-68. Epub 2011 Aug 31.  PMID: 21885430, PMCID: PMC3220284. 

Kristian T, Balan I, Schuh R, Onken M.  Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection. J Neurosci Res. 2011 Dec; 89(12):1946-55. doi: 10.1002/jnr.22626. Epub 2011 Apr 12. Review.  PMID: 21488086 

Lissauer ME, Smitz Naranjo L, Kirchoffner J, Scalea TM, Johnson SB.  Patient Characteristics Associated with End-of-Life Decision Making in Critically Ill Surgical Patients.  Journal of the American College of Surgeons, 2011 Dec; 213(6):766-70.  PMID: 22107920.  

Wang H, Sreenevasan U, Hu H, Saladino A, Polster BM, Lund LM, Gong DW, Stanley WC, Sztalryd C.  Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria. J Lipid Res. 2011  Dec;52(12):2159-68. Epub 2011 Aug 31. PMID: 21885430. PMCID: PMC3220284 

Schuh, R.A., Clerc, P., Hwang, H., Mehrabian, Z., Bittman, K., Chen, H., and Polster, B.M. Adaptation of microplate-based respirometry for hippocampal slices and analysis of respiratory capacity. J. Neurosci. Res. J Neurosci Res. 2011 Dec; 89(12):1979-88. doi: 10.1002/jnr.22650. Epub 2011 Apr 21.  PMID: 21520220.  PMCID: PMC3144988 

Chi A, Lissauer ME, Kirchoffner J, Scalea TM, Johnson SB. Effect of Glycemic State on Hospital Mortality in Critically Ill Surgical Patients. American Surgeon, 2011 Nov; 77(11):1483-9.  PMID: 22196662 

Thornley S, Kool B, Robinson E, Marshall R, Smith GS, Ameratunga S.  Alcohol and risk of admission to hospital for unintentional cutting or piercing injuries at home: a population-based case-crossover study.  BMC Public Health. 2011 Nov 9; 11:852. PMID: 22070787.  PMCID: PMC3247204 

Devabhakthuni S, Pajoumand M, Williams C, Stein DM, Watson K.  Evaluation of Dexmedetomidine: Safety and clinical outcomes in critically ill trauma patients.  J Trauma. 2011 Nov; 71(5):1164-71. PMID: 21502875 

Li J, Amr S, Braver ER, Langenberg P, Zhan M, Smith GS, Dischinger PC.  Are current law enforcement strategies associated with a lower risk of repeat speeding citations and crash involvement? A longitudinal study of speeding Maryland drivers.  Ann Epidemiol. 2011 Sep; 21(9):641-7.  PMID: 21684176. 

Menaker J, Farcy D, Boswell SA, Stein DM, Dutton RP, Hess JR, Scalea TM.  Cocaine-induced agitated delirium and associated hyperthermia – A case report. J Emerg Med.  2011 Sep; 41(3):e49-53. Epub 2008 Sep 26. PMID: 18823733 

Byrnes KR, Washington PM, Knoblach SM, Hoffman E, Faden AI. Delayed inflammatory mRNA and protein expression after spinal cord injury. Journal of Neuroinflammation 8(1):130, Oct. 2011. [Epub ahead of print]. PMID: 21975064 

Xu S, Zhuo J, Racz J, Shi D, Roys SR, Fiskum G, Gullapalli R., Early microstructural and metabolic changes following controlled cortical impact injury in rat: A magnetic resonance imaging and spectroscopy study. J Neurotrauma. 2011 Oct; 28(10):2091-102. Epub 2011 Sep 29.  (PMID: 21761962) 

Kabadi SV, Stoica BA, Loane DJ, Byrnes KR, Hanscom M, Cabatbat RM, Tan MT, Faden AI. Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury. Journal of Neurotrauma, Sept 2011 [Epub ahead of print]. PMID: 21895533 

De Biasi AR, Stansbury LG, Dutton RP, Stein DM, Scalea TM, Hess JR.  Blood product use in trauma resuscitation:  Plasma deficit versus plasma ratio as predictors of mortality in trauma.  Transfusion. 2011 Sep;51(9):1925-32. doi: 10.1111/j.1537-2995.2010.03050.x. Epub 2011 Feb 18.  PMID: 21332727 

Faden, AI. Microglial activation and traumatic brain injury. Annals of Neurology, 70: 345–346, Sept 2011. PMID: 21905075 

Ryb GE, Dischinger PC. Scene Mobility Status as a Predictor of Injury Severity and Mortality due to Vehicular Crashes.   J Trauma. 2011 Sep; 71(3):737-41.  PMID: 21909003 

Ryb GE, Dischinger PC.  Disparities in Trauma Center Access of Injured Older Motor Vehicular Crash Occupants.   J Trauma. 2011 Sep; 71(3):742-7.  PMID: 21909004 

de Biasi AR, Stansbury LG, Dutton RP, Stein DM, Scalea TM, Hess JR.  Blood product use in trauma resuscitation: plasma deficit versus plasma ratio as predictors of mortality in trauma.  Transfusion. 2011 Sep;51(9):1925-32. doi: 10.1111/j.1537-2995.2010.03050.x. Epub 2011 Feb 18.  PMID: 21332727.  PMCID: PMC3138868 

Levi M, Fries D, Gombotz H, Linden Ph. Van der, Nascimento B, Scalea TM, et al.  Prevention and treatment of coagulopathy in patients receiving massive transfusions.  International Society of Blood Transfusion.  Vox Sanguinis.  2011 Aug;101(2):154-74. doi: 10.1111/j.1423-0410.2011.01472.x. PMID: 21749403 

Narayan M, Scalea T.  Ruptured horseshoe kidney.  Journal of Trauma. 2011 Aug; 71 (2):516.  PMID: 21825953 

Anand RJ, Ferrada PA, Darwin PE, Bochicchio GV, Scalea TM.  Endoscopic retrograde cholangiopancreatography is an effective treatment for bile leak after severe liver trauma.  Journal of Trauma.  2011 Aug; 71(2):480-5.  PMID: 21206287. 

Stein DM, Hu P, Brenner M, Sheth K, Liu K, Aarabi B, Scalea TM. Brief episodes of intracranial hypertension and cerebral hypoperfusion are associated with poor functional outcome following severe traumatic brain injury.  J Trauma. 2011 Aug; 71(2):364-73; discussion 373-4.  PMID: 21825940 

Kabadi SV, Stoica BA, Byrnes, KR, Hanscom M, Loane DJ, Faden AI. Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma. Journal of Cerebral Blood Flow and Metabolism, Aug 2011 [Epub ahead of print]. PMID: 21829212 

Mayglothing JA, Haan JM, Scalea TM.  Blunt splenic injuries in the adolescent trauma population:  The role of angiography and embolization.  Journal of Emergency Medicine.  2011 Jul; 41(1):21-8. Epub 2009 Jan 31.  PMID: 19181474. 

McCunn M, York GB, Hirshon JM, Jenkins DH, Scalea TM.  Trauma readiness training for military deployment:  a comparison between a U.S. trauma center and an air force theater hospital in Balad, Iraq.  Military Medicine, 2011 Jul; 176 (7):769-76.  PMID: 22128718.   

Lombardi DA, Folkard S, Willetts JL, Smith GS.  Daily sleep, weekly working hours, and risk of work-related injury: US National Health Interview Survey (2004-2008).  Chronobiol Int. 2010 Jul;27(5):1013-30. PMID: 20636213  

Chiu W, Marcolini E, Simmons D, Yeatts D, Scalea TM.  Training dedicated emergency physicians in surgical critical care:  knowledge acquisition and workforce collaboration for the care of critically ill trauma/surgical patients.  Journal of Trauma.  2011 Jul; 71(1):43-8. PMID: 21818013 

Polster, B.M., Aja, S.M., Pletnikov, M.V., Kensler, T.W., Shirihai, O.S., Iijima, M., Hussain, M.A., and Sesaki, H. The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells.   Mol Biol Cell. 2011 Jul 1;22(13):2235-45. Epub 2011 May 5.  PMID: 21551073.  PMCID: PMC3128526 

Lane W, Lotkin I, Dubowitz H, Lange P, Dischinger P. Outcomes for children hospitalized with abusive abdominal trauma vs. non-inflicted abdominal trauma. Pediatrics 2011 Jun; 127(6):e1400-5. Epub 2011 May. PMID: 21555490 

De Castro G, MacPhee M, Driscoll I, Beall D, Hsu J, Zhu S, Hess J, Scalea T, Bochicchio G.  New hemostatic dressing (FAST Dressing) reduces blood loss and improves survival in grade V liver injury model.  Journal of Trauma, 2011 Jun; 70(6):1408-12. PMID: 21817977 

Stein DM, Lindell A, Murdock KR, Kufera JA, Menaker J, Keledjian K, Bochicchio GV, Aarabi B, Scalea TM.  Relationship of serum and cerebrospinal fluid biomarkers with intracranial hypertension and cerebral hypoperfusion after severe traumatic brain injury.  J Trauma. 2011 May;70(5):1096-103. PMID: 21610426 

Sheth KN, Gilson AJ, Chang Y, Kumar MA, Rahman RM, Rost NS, Schwab K, Cortellini L, Goldstein JN, Smith EE, Greenberg SM, Rosand J.  Packed Red Blood Cell Transfusion and Decreased Mortality in Intracerebral Hemorrhage.  Neurosurgery. 2011 May;68(5):1286-92. PMID: 21307801 

Lissauer M, Chi A, Kramer M, Scalea TS, Johnson SB. Association of 6% Hetastarch Resuscitation with Adverse Outcomes in Critically Ill Trauma Patients. American Journal of Surgery. Am J Surg. 2011 Jul;202(1):53-8. Epub 2011 May 19. PMID: 21600555 

Halonen-Watras J, O’Connor JV, Scalea TM.  Traumatic Pneumonectomy:  A viable option for patients in extremis.  The American Surgeon. 2011 Apr; 77(4):493-7.  PMID: 21679563 

Wu J, Stoica B, Faden AI (2011) Cell cycle activation and spinal cord injury. Neurotherapeutics, Apr 2011; 8(2):221-8. PMID: 21373950

Ibrahim JM, Day H, Hirshon JM, El-Setouhy M. Road risk-perception and pedestrian injuries among students at Ain Shams University, Cairo, Egypt. J Inj Violence Res. doi: 10.5249/jivr.v4i2.112. April 2011. PMID: 21502783

Simard JM, Sahuquillo J, Sheth KN, Kahle KT, Walcott BP. Managing Malignant Cerebral Infarction. Curr Treat Options Neurol 2011 Apr; 13(2):217-29. PMID: 21190097 

Brenner M, Bochicchio G, Bochicchio K, Ilahi O, Rodriguez E, Henry S, Joshi M, Scalea T.  Long-term impact of damage control laparotomy.  Arch Surg. 2011 Apr; 146(4):395-9. Epub 2010 Dec 20.  PMID: 21173282 

Stein DM, Kufera JA, Lindell A, Murdock KR, Menaker J, Bochicchio GV, Aarabi B, Scalea TM. Association of CSF Biomarkers and Secondary Insults Following Severe Traumatic Brain Injury. Neurocrit Care. 2011 Apr;14(2):200-7.  PMID: 21210304 

Kahraman S, Hu P, Stein DM, Stansbury LG, Hess JR, Xiao Y, Dutton RP, Scalea TM.  Dynamic three-dimensional scoring of cerebral perfusion pressure and intracranial pressure provides a brain trauma index that predicts outcome in patients with severe traumatic brain injury.  Journal of Trauma.  2011 Mar;70(3):547-53.  PMID: 21610341 

Hinson HE, Stein D, Sheth KN. Hypertonic Saline and Mannitol Therapy in Critical Care Neurology. J Intensive Care Medicine. 2011 Mar 24. [Epub ahead of print] PubMed PMID: 21436162 

Malek J, Rogers R, Kufera J, Hirshon JM. Venous thromboembolic disease in the HIV-infected patient. Am J Emerg Med. 2011 Mar;29(3):278-82. Epub 2010 Mar 26. PMID: 20825798

Menaker J, Joseph B, Stein DM, Scalea TM. Angiointervention: High rates of failure following blunt renal injuries. World J Surg. 2011 Mar; 35(3):520-7. PMID: 21190111 

Prior K, Cohen R, Dutton RP, Wade C, Sewell J, Fouche Y, Stein DM, Aarabi B, Scalea TM. Diagnosing mTBI: Where are we now?  J Trauma. 2011 Mar; 70(3):554-9.  PMID: 21610342. 

Stein DM, Kufera JA, Ho SM, Ryb GE, Dischinger PC, O’Connor JV, Scalea TM.  Occupant and crash characteristics for case occupants with cervical spine injuries sustained in motor vehicle collisions.  Journal of Trauma.  2011 Feb; 70(2):299-309.  PMID: 21307725 

Toman, J. and Fiskum, G., Influence of aging on membrane permeability transition in brain mitochondria. J Bioenerg Biomembr. 2011 Feb;43(1):3-10. Review.  PMID: 21311961 

Weingart SD, Menaker J, Truong H, Bochicchio K, Scalea TM.  Trauma patients can safely be extubated in the Emergency Department.  J Emerg Med. 2011 Feb; 40(2):235-9. Epub 2009 Aug 22.  PMID: 19703744 

Kimberly WT, Sheth KN. Approach to Hemispheric Stroke. Neurology 2011 Feb; 76(7 Suppl 2):S50-6. PMID: 21321352

Wu J, Leung PY, Sharp A, Lee HJ, Wrathall JR (2011) Increased expression of the close homolog of the adhesion molecule L1 (CHL1) in different cell types over time after rat spinal cord contusion. Journal of Neuroscience Research, May 2011; 89(5):628-38. doi: 10.1002/jnr.22598. Epub  Feb 2011. PMID: 21337374

Willis M, Neschis D, Menaker J, Lilly M, Scalea T. Stent grafting for a distal thoracic aortic injury. Vasc Endovascular Surg 2011 Feb; 45(2):187-90 PMID: 21382836

Perez DL, Diamond EL, Castro CM, Diaz A, Buonanno F, Nogueira R, Sheth K. Factor XIII deficiency related recurrent spontaneous intracerebral hemorrhage: a case and literature review. Clin Neurol Neurosurg 2011 Feb; 113(2):142-5. Epub 2010 Oct 14. PMID: 20950938.

Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, FADEN AI, Burns MP. Modulation of ABCA1 by an LXR antagonist reduces beta-amyloid levels and improves outcome after traumatic brain injury. J Neurotrauma 28(2): 225-236, 2011 Feb. PMID:21175399 

DuBose J, Barmparas G, Inaba K, Stein DM, Scalea TM, Cancio L, Cole J, Eastridge B, Blackbourne L. Isolated Severe Traumatic Brain Injuries Sustained During Combat Operations: Demographics, Mortality Outcomes and Lessons to be Learned from Contrasts to Civilian Counterparts. J Trauma. 2011, Jan; 70(1):11-18. PubMed PMID: 21217475

Inaba K, DuBose J, Bamparas G, Barbarino R, Reddy S, Talving P, Lam L, Demetriades D. Clinical examination is insufficient to rule out thoracolumbar spine injuries. J Trauma. 2011 Jan; 70(1):174-9. PubMed PMID: 20489662

Ryb GE, Dischinger PC, Diclemente C, Auman KM, Kufera JA, Soderstrom CA. Impulsive or depressive personality traits do not impede behavioral change after brief alcohol interventions. J Addict Dis 2011 Jan; 30 (1):54-62. PMID: 21218311 

Dubose JJ, Barmparas G, Inaba K, Stein DM, Scalea T, Cancio LC, Cole J, Eastridge B, Blackbourne L.  Isolated severe traumatic brain injuries sustained during combat operations:  demographics, mortality outcomes and lessons to be learned from contrasts to civilian counterparts.  Journal of Trauma, 2011 Jan; 70(1):11-6; discussion 16-8. PMID: 21217475 

Ferrada P, Murthi S, Anand R, Bochicchio G, Scalea T.  Transthoracic focused rapid echocardiographic examination:  real-time evaluation of fluid status in critically ill trauma patients.  Journal of Trauma.  2011 Jan;70(1):56-62; discussion 62-4. PMID: 21217482 

Ryb GE, Dischinger PC., McGwin G, Griffin RL. Crash-Related Mortality and Model Year: Are Newer Vehicles Safer? Ann Adv Automot Med. 2011; 55:113-21.  PMID: 22105389.  PMCID: PMC3256831 

Ryb GE, Dischinger PC.  Improving Trauma Triage Using Basic Crash Scene Data. Annu Proc Assoc Adv Automot Med. 2011; 55:337-46.  PMID: 22105408.  PMCID: PMC3256812 

Stein DM, Lindell A, Murdock KR, Kufera JA, Menaker J, Keledjian K, Bochicchio GV, Aarabi B, Scalea TM.  Relationship of serum and CSF biomarkers to intracranial hypertension and cerebral hypoperfusion following severe traumatic brain injury.  J Trauma. 2011; 70(5):1096-103. PMID: 21610426. 

2010  

Scafidi, S., Racz, J., Hazelton, J., McKenna, M.C., and Fiskum, G., Neuroprotection by acetyl-L-carnitine after traumatic injury to the immature rat brain, Develop. Dev Neurosci. 2010;32(5-6):480-7. Epub 2011 Jan 12.  PMID: 21228558, PMCID: PMC3073762. 

Baldwin KM, Ryb GE, Miller D, Counihan TC, Brotman S. Is spine consultation needed for all thoracolumbar fractures? Evaluation of a subspecialist-sparing protocol for screening and management of stable fractures. J Trauma. 2010 Dec;69(6):1491-5; discussion 1495-6.  PMID: 21150528 

Greco, T. and Fiskum, G., Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition, J Bioenerg Biomembr. 2010 Dec;42(6):491-7.   (PMID: 20463397) 

Loane DJ, Faden AI. Neuroprotection and traumatic brain injury: translational challenges and emerging therapeutic strategies. Trends in Pharmacol Sci 2010 Dec; 31(12):596-604. Epub 2010 Oct 29. PubMed PMID: 21035878 

Bamparas G, Inaba K, Teixeira PGR, DuBose J, Criscuoli M, Talving P, Plurad D, Green MD. Demetriades D. Epidemiology of post-traumatic limb amputaton: A National Trauma Databank analysis. Am Surg. 2010 Nov; 76(11):1214-22. PubMed PMID: 21140687 

Onken M, Berger S, Kristian T.  Simple model of forebrain ischemia in mouse.  J Neurosci Methods. 2012 Mar 15;204(2):254-61. Epub 2011 Nov.  PMID: 22146544 

Byrnes, Fricke ST, Faden AI. Neuropathological differences between rats and mice after spinal cord injury. J Magn Reson Imaging. 2010 Oct; 32(4):836-46.  PMID: 20882614. PMCID: PMC2949295 

Ryb GE, Cooper C.   Race/ethnicity and acute respiratory distress syndrome: a National Trauma Data Bank study.J Natl Med Assoc. 2010 Oct; 102(10):865-9. PMID: 21053700 

Kahraman S, Dutton RP, Hu P, Stansbury LG, Xiao Y, Stein D, Scalea T.  Heart rate and pulse pressure variability are associated with intractable intracranial hypertension after severe traumatic brain injury. J Neurosurg Anesthesiol. 2010 Oct; 22(4):296-302.  PMID: 20622688 

Bochicchio GV, Bochicchio KM, Joshi M, Ilahi O, Scalea TM.  Acute glucose elevation is highly predictive of infection and outcome in critically injured trauma patients.  Annals of Surgery.  2010 Oct;252(4):597-602.  PMID: 20881765 

Cernak I, Chang T, Ahmed FA, Cruz MI, Vink R, Stoics B, Faden AI. Pathophysiological responses to experimental diffuse brain trauma differs as a function of developmental age. Dev Neurosci. 2010; 32(5-6):442-53. Epub 2010 Oct 14.  PMID: 20948187 

Day HR, El-Setouhy M, El-Shinawi M, Assem A, Ismail M, Salem M, Smith GS, Hirshon JM. Young Egyptians' perceptions, attitudes and knowledge of injuries. Inj Prev. 2010 Oct; 16 (5):348-51. Epub 2010 Jun 29.  PMID: 20587813 

Menaker J, Scalea TM. Geriatric care in the surgical intensive care unit. Crit Care Med. 2010 Sep; 38(9 Suppl):S452-9. PubMed PMID: 20724878. 

Dabbs DN, Stein DM, Philosophe B, Scalea TM. Treatment of major hepatic necrosis: Lobectomy versus serial debridement. J Trauma. 2010 Sep;69(3):562-7.  PMID: 20838127 

Gregg SC, Murthi SB, Sisley AC, Stein DM, Scalea TM.  Ultrasound-guided peripheral intravenous access in the intensive care unit.  Journal of Critical Care.  2010 Sep;25(3):514-9. Epub 2009 Oct 15.  PMID: 19836193 

Dutton RP, Stansbury LG, Leone S, Kramer E, Hess JR, Scalea TM.  Trauma mortality in mature trauma system:  are we doing better?  An analysis of trauma mortality patterns, 1997-2008.  Journal of Trauma.  2010 Sep;69(3):620-6.  PMID: 20093983 

Kabadi SV, Hilton GD, Stoica BA, Zapple DN, Faden AI. Fluid-percussion-induced traumatic brain injury model in rats. Nat Protoc. 2010 Sep; 5(9):1552-63. Epub 2010 Aug 19.  PMID: 20725070 

Khairallah, R.J. Sparagna, G.C., Khanna, N., O’Shea, K.M., Hecker, P.A., Kristian, T., Fiskum, G., Des Rosiers, C., Polster, B.M., and Stanley, W.C. (2010) Dietary Supplementation with Docosahexaenoic Acid, but Not Eicosapentanoic Acid, Dramatically Alters Cardiac Mitochondrial Phospholipid Fatty Acid Composition and Prevents Permeability Transition.  Biochim Biophys Acta. 2010 Aug; 1797(8):1555-62. Epub 2010 May 21.  PMID: 20471951, PMCID: PMC3071681. 

Stein DM, Menaker J, McQuillan K, Handley C, Aarabi B, Scalea TM.  Risk factors of organ dysfunction and failure in patients with acute traumatic cervical spinal cord injury.  Neurocrit Care. 2010 Aug; 13(1):29-39.  PMID: 20407933 

Stein DM, Menaker J, McQuillan K, Handley C, Aarabi B, Scalea TM. Risk factors for organ dysfunction and failure in patients with acute traumatic cervical spinal cord injury. Neurocrit Care. 2010 Aug; 13(1):29-39. PubMed PMID: 20407933. 

Thunberg CA, Gaitan BD, Arabia FA, Cole DJ, Grigore AM.  Ventricular Assist Devices Today and Tomorrow. Journal of Cardiothoracic and Vascular Anesthesia J Cardiothorac Vasc Anesth 24:656-680, 2010.  J Cardiothorac Vasc Anesth. 2010 Aug; 24(4):656-80. Epub 2010 Feb 16. Review. PMID: 20163969 

Scafidi S, Fiskum G, Lindauer SL, Bamford P, Shi D, Hopkins I, McKenna MC. Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain. J Neurochem. 2010 Aug; 114(3):820-31. Epub 2010 May 13. PubMed PMID: 20477950. 

Kristian T. Isolation of mitochondria from the CNS. Curr Protoc Neurosci. 2010 Jul; Chapter 7: Unit 7.22. PubMed PMID: 20578034.

Kahraman S, Dutton RP, Hu P, Xiao Y, Aarabi B, Stein DM, Scalea TM. Automated measurement of "pressure times time dose" of intracranial hypertension best predicts outcome after severe traumatic brain injury. J Trauma. 2010 Jul; 69(1):110-8. PubMed PMID: 20038855. 

Bukur M, Inaba K, Barmparas G, Dubose JJ, Lam L, Branco BC, Lustenberger T, Demetriades D. Self-inflicted penetrating injuries at a Level I Trauma Center. Injury. 2010 Jul; 41(7):1013-6. PubMed PMID: 20359709 

Pajoohesh-Ganji A, Byrnes KR, Fatemi G, Faden AI. A combined scoring method to assess behavioral recovery after mouse spinal cord injury. Neurosci Res. 2010 Jun;67(2):117-25. Epub 2010 Feb 25. PMID: 20188770

Dubose J, Inaba K, Barmparas G, Teixeira PG, Schnüriger B, Talving P, Salim A, Demetriades D. Bilateral Internal Iliac Artery Ligation as a Damage Control Approach in Massive Retroperitoneal Bleeding After Pelvic Fracture. J Trauma. 2010 May 20. [Epub ahead of print] PubMed PMID: 20495490.   

 Khairallah RJ, Sparagna GC, Khanna N, O'Shea KM, Hecker PA, Kristian T, Fiskum G, Des Rosiers C, Polster BM, Stanley WC. Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition. Biochim Biophys Acta. 2010 Aug; 1797(8):1555-62. Epub 2010 May 21. PubMed PMID: 20471951. 

Ryb GE, Burch C, Kerns T, Dischinger PC, Ho S. Crash test ratings and real-world frontal crash outcomes: a CIREN study. J. Trauma. 2010 May; 68(5):1099-105. PubMed PMID: 20453764. 

Voss SE, Adegoke MF, Horton NJ, Sheth KN, Rosand J, Shera CA.  Posture systematically alters ear-canal reflectance and DPOAE properties.  Hear Res. 2010 May; 263(1-2):43-51. Epub 2010 Mar 19. PMID: 20227475.  PMCID: PMC3179977 

Soane L, Li Dai W, Fiskum G, Bambrick LL. Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation. J Neurosci Res. 2010 May 1; 88(6):1355-63. PubMed PMID: 19998483.

Kim PD, Ludwig S, Poelstra K, Duggan B, Scalea T, Gelb D. Ectopic bone formation in the pelvis after combined anterior and posterior fusion of the spine with osteogenic protein-1 use: a case report. J Spinal Disord Tech. 2010 May; 23(3):215-20. PubMed PMID: 20084023.

Ryb GE, Dischinger PC, Burch C, Kerns T.  Crash test rating and real-world frontal crash outcomes: a CIREN study. J Trauma. 2010 May; 68(5):1099-105.  PMID: 20453764 

DuBose JJ, Kobayashi L, Lozornio A, Teixeira P, Inaba K, Lam L, Talving P, Branco B, Demetriades D, Rhee P. Clinical experience using 5% hypertonic saline as a safe alternative fluid for use in trauma. J. Trauma. 2010 May; 68(5):1172-7. PubMed PMID: 20453771.  

Layton B, Dubose J, Nichols S, Connaughton J, Jones T, Pratt J. Pacifying the open abdomen with concomitant intestinal fistula: a novel approach. Am J Surg. 2010 Apr; 199(4):e48-50. PubMed PMID: 20359566.

O'Connor JV, Scalea TM. Penetrating thoracic great vessel injury: impact of admission hemodynamics and preoperative imaging. J. Trauma. 2010 Apr;68(4):834-7. PubMed PMID: 20065882.

Layton B, DuBose J, Nichols S, Connaughton J, Jones T, Pratt J.  Pacifying the open abdomen with concomitant intestional fistula: A novel approach.  Am J Surg. 2010 Apr; 199(4):e48-50. PubMed PMID: 20359566 

Hazelton JL, Balan I, Elmer GI, Kristian T, Rosenthal RE, Krause G, Sanderson TH, Fiskum G. Hyperoxic reperfusion after global cerebral ischemia promotes inflammation and long-term hippocampal neuronal death. J Neurotrauma. 2010 Apr; 27(4):753-62. PubMed PMID: 20059303; PubMed Central PMCID: PMC2867550.

Cohn SM, Dubose JJ. Pulmonary Contusion: An Update on Recent Advances in Clinical Management. World J Surg. 2010 Apr 21. [Epub ahead of print] PubMed PMID: 20407767.

D'Alleyrand JC, Dutton RP, Pollak AN. Extrapolation of battlefield resuscitative care to the civilian setting. J Surg Orthop Adv. 2010 Spring; 19(1):62-9. PubMed PMID: 20371009.

O’Connor JV, Scalea TM.  Penetrating great vessel injury:  Impact of admission hemodynamics and pre-operative imaging.  Journal of Trauma.  2010 Apr;68(4):834-7. PMID: 20065882 

Claassen CW, O’Connor JV, Gens D, Sikorski R, Scalea TM.  Penetrating cardiac injury: Think outside the box.  Journal of Trauma. 2010 Mar; 68(3):E71-3. PMID: 20220405 

Bochicchio GV, Kilbourne MJ, Keledjian K, Hess J. Scalea T.  Evaluation of a new hemostatic agent in a porcine grade V liver injury model.  The American Surgeon.  2010 Mar;76(3):317-20.  PMID: 20349664 

Como JJ, Bokhari F, Chiu WC, Duane TM, Holevbar MR, Tandoh MA, Ivatury RR, Scalea TM.  Practice management guidelines for selective nonoperative management of penetrating abdominal trauma.  J Trauma. 2010 Mar;68(3):721-33.  PMID: 20220426 

Dutton RP. Making medics smarter. Crit Care Med. 2010 Mar;38(3):992-3. PubMed PMID: 20168160.

Balan IS, Fiskum G, Kristian T. Visualization and quantification of NAD(H) in brain sections by a novel histo-enzymatic nitrotetrazolium blue staining technique. Brain Res. 2010 Feb 26;1316:112-9. Epub 2009 Dec 28. PubMed PMID: 20036220; PubMed Central PMCID: PMC2822014.

Talving P, Plurad D, Barmparas G, Dubose J, Inaba K, Lam L, Chan L, Demetriades D. Isolated severe traumatic brain injuries: association of blood alcohol levels with the severity of injuries and outcomes. J Trauma. 2010 Feb;68(2):357-62. PubMed PMID: 20154549. 

Sheth KN, Cushing TA, Wendell L, Lev MH, Romero JM, Schwab K, Smith EE, Greenberg SM, Rosand J, Goldstein JN.  Comparison of hematoma shape and volume estimates in warfarin vs non-warfarin related intracerebral hemorrhage.  Neurocrit Care. 2010 Feb; 12(1):30-4.  PMID: 19859832.  PMCID: PMC2818373 

Jones WT, Pratt J, Connaughton J, Nichols S, Layton B, DuBose J. Management of a nontraumatic extracranial internal carotid aneurysm with external carotid transposition. J Vasc Surg. 2010 Feb;51(2):465-7. Epub 2009 Sep 26. PubMed PMID: 19782514.

Levy JH, Dutton RP, Hemphill JC 3rd, Shander A, Cooper D, Paidas MJ, Kessler CM, Holcomb JB, Lawson JH; Hemostasis Summit Participants. Multidisciplinary approach to the challenge of hemostasis. Anesth Analg. 2010 Feb;110(2):354-64. Epub 2009 Dec 10. Review. PubMed PMID: 20007735.   

Wu J, Wrathall JR, Schachner M. Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. Glia. 2010 Feb;58(3):315-28. PubMed PMID: 19672967; PubMed Central PMCID: PMC2795071.

Menaker J, Stein DM, Philp AS, Scalea TM.  40-Slice multidector CT:  Is MRI still necessary for cervical spine clearance after blunt trauma?  The American Surgeon.  2010 Feb;76(2):157-63.  PMID: 20336892 

Dutton RP, Stansbury LG, Leone S, Kramer E, Hess JR, Scalea TM. Trauma Mortality in Mature Trauma Systems: Are We Doing Better? An Analysis of Trauma Mortality Patterns, 1997-2008. J Trauma. 2010 Jan 20. [Epub ahead of print] PubMed PMID: 20093983.

Padurariu M, Ciobica A, Hritcu L, Stoica B, Bild W, Stefanescu C. Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease. Neurosci Lett. 2010 Jan 18;469(1):6-10. Epub 2009 Nov 13. PubMed PMID: 19914330.

Sonna LA, Hawkins L, Lissauer ME, Maldeis P, Towns M, Johnson SB, Moore R, Singh IS, Cowan MJ, Hasday JD. Core temperature correlates with expression of selected stress and immunomodulatory genes in febrile patients with sepsis and noninfectious SIRS. Cell Stress Chaperones. 2010 Jan;15(1):55-66. Epub 2009 Jun 4. PubMed PMID: 19496026. 

Stoica BA, Faden AI. Cell death mechanisms and modulation in traumatic brain injury. Neurotherapeutics. 2010 Jan;7(1):3-12. PubMed PMID: 20129492.

Talving P, DuBose J, Inaba K, Demetriades D. Conversion of emergent cricothyrotomy to tracheotomy in trauma patients. Arch Surg. 2010 Jan;145(1):87-91. Review. PubMed PMID: 20083759.

Salim A, Ottochian M, DuBose J, Inaba K, Teixeira P, Chan LS, Margulies DR. Does insurance status matter at a public, level I trauma center? J Trauma. 2010 Jan;68(1):211-6. PubMed PMID: 20065777.  

Anderson D, Ryb GE, Dischinger PC, Kufera J, Read KM. Self-Reported Health Indicators in the Year Following a Motor Vehicle Crash: A Comparison of Younger vs. Older Subjects. Ann Adv Automot Med. 2010; 54:359-67.  PMID: 21050618 

Greco, T. and Fiskum, G., Neuroprotection through stimulation of mitochondrial antioxidant protein expression. J Alzheimers Dis. 2010;20 Suppl 2:S427-37. Review.  PMID: 20463397