Farber Lab

Selected Publications

Ahmazadeh, M., Hussain, S.F. and Farber, D.L. (2001) Heterogeneity of the memory CD4 T cell response: persisting effectors and resting memory T cells. J. Immunol. 166:926-935. (PDF file)

Krishnan, S., Warke, V., Wong, H., Nambiar, M., Tsokos, G., and Farber, D.L. (2001) Generation and Biochemical Analysis of human effector CD4 T cells: alterations in tyrosine phosphorylation and loss of CD3ζ expression. Blood. 97:3851-59 (PDF file)

Hussain, S.F., Anderson, C.A. and Farber, D.L. (2002) Differential SLP-76 expression and TCR-mediated signaling in effector and memory CD4 T cells. J. Immunol. 168:1557-1565. (PDF file)

Ahmadzadeh, M. and Farber, D.L. (2002) Functional Plasticity of an antigen-specific memory CD4 T cell population. Proc. Natl'l Acad. Sci, U.S.A. 99:11802-11807. (PDF file)

Feng, Y., Wang, D, Yuan, R., Farber, D.L. and Hadley, G.A. (2002). CD103 expression is required for destruction of pancreatic islet allografts by CD8 T cells. J. Exp. Med. 196:877-886. Commentary in J. Exp. Med. 196:873-875. (PDF File)

Krishnan, S., Warke, V, Nambiar, M.P., Tsokos, G.C., and Farber, D.L. (2003) The FcRγ subunit and Syk kinase replace CD3 and ZAP-70 in the TCR/CD3 signaling complex of human effector CD4 T cells. J. Immunol. 170: 4189-4195. (PDF file)

Krishnan, S., Farber, D.L., and Tsokos, G.C. (2003) T cell rewiring in differentiation and disease. J. Immunol. 171: 3325-3331 (PDF file)

Lai, W., Chang, C.-H., and Farber, D.L. (2003) Gene transfection and expression in resting and activated subsets of murine CD4 T cells. J. Immunol. Meth. 282: 93-102. (PDF file)

Bingaman, A.W. and Farber, D.L. (2004) Memory T cells in Transplantation: Generation, function and potential role in rejection. Am. J. Transplantation. 4:846-852. (PDF file)

Shi, Q., Wang, D.-W., Hadley, G.A., Bingaman, A.W., Bartlett, S.T, and Farber, D.L. (2004) Long-term islet graft survival in NOD mice by abrogation of recurrent autoimmunity. Diabetes. 53:2338-45. (PDF file)

Chandok, M. and Farber, D.L. (2004) Signaling Control of Memory T cell generation and function. Seminars in Immunology. 16:285-93. (PDF file)

Patke, D.S. and Farber, D.L. (2005) Modulation of memory CD4 T cell function and survival potential by altering the strength of the recall stimulus. J. Immunol. 174:5433-5443. (PDF file)

Bingaman, A.W., Patke, D.S., Mane, V., Bartlett, S.T., and Farber, D.L. (2005) Novel phenotypes and migration properties distinguish memory CD4 T cell subsets in lymphoid and lung tissue. Eur. J. Immunol. 35:3173-86. (PDF file) Highlighted In this Issue 35:3085-6. (PDF file)

Patke, D., Ahmadzadeh, M, Bingaman, A.W. and Farber, D.L. (2005) Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells . Clinical Immunology. 117:125-32. (PDF file) Commentary in same issue by Milone, M.C. and June, C.H.. “Adoptive immunotherapy: new ways to skin the cat?” pp.101-103. (PDF file)

Tang, A.L., Bingaman, A.W., Kadavil, E.A., Leeser, D.B., and Farber, D.L. (2006)Generation and functional capacity of polyclonal alloantigen-specific memory CD4 T cells. Am. J. Transplant. 6:1275-1284. (PDF) (editorial in the same issue by Fairchild, R., “Developing models to study the memory T cell barrier in transplantation”, 6:1246-7)

 

Moulton, V., Bushar, N., Leeser, D., Patke, D.S. and Farber, D.L.  (2006) Divergent generation of heterogeneous memory CD4 T cells. J. Immunol. 177: 869-876.  (PDF)

 

Moulton, V. and Farber, D.L. (2006) Committed to memory: lineage choices for T cells. Trends Immunol.  27: 261-67. (PDF)

 

Ndejembi, M.P., Patke, D.S., Bingaman, A.W., Chandok, M.R., Azimzadeh, A., Nadler, S.G., and Farber, D.L. (2006) Control of Memory CD4 T cell recall by the CD28 costimulatory pathway.  J. Immunol. 177: 7698-7706. (PDF)

 

Zhang, X., Dong, H., Lin. W., Voss, S., Hinkley, L., Westergren, M., Berry, D., Lewellen,D., Vile, R.  Chen, L., Farber, D.L., and Strome, S.E. (2006)  Human Bone Marrow: a reservoir for enhanced effector-memory CD8 T Cells with potent recall function. J. Immunol. 177: 6730-7. (PDF) 

 

Ndejembi, M.P., Tang, A.L. and Farber, D.L. (2007) Reshaping the Past: strategies for modulation of T cell memory. Clinical Immunology. 122:1-12.

(PDF)

 

Tang, A.L. and Farber, D.L.  (2007) Generation, homeostasis, and regulation of memory T cells in Transplantation. Current Opinion in Organ Transplantation. 12:23-29. (PDF)

 

Chandok, M.R., Okoye, F.I., Ndejembi, M.P. and Farber, D.L. (2007) A biochemical signature for rapid recall by memory CD4 T cells. J. Immunol.  179:3689-98. (PDF)

 

Okoye, F.I., Krishnan, S., Chandok, M.R., Tsokos, G.C., and Farber, D.L. (2007)  Proximal Signaling control of human CD4 T cell function. Clin. Immunol. 125:5-15. (PDF)

 

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