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Nirav G Shah

Nirav G Shah M.D.

Academic Title: Assistant Professor
Primary Appointment: Medicine
Location: 110 S. Paca Street, 2N-144
Phone: (410) 328-8141
Fax: (410) 328-0177

Personal History:

Dr. Shah graduated from the University of North Carolina in Chapel Hill, North Carolina with a BS in Biology with Honors and a minor in Chemistry and then went on to pursue his medical education at St. George's University School of Medicine in Grenada, West Indies. Upon graduating from St. George's University with Honors, he did his internship and residency in Internal Medicine at the Washington Hospital Center in Washington, D.C. He completed his fellowship in Critical Care Medicine at the National Institutes of Health and his fellowship in Pulmonary Diseases at the University of Maryland Medical Center. Dr. Shah is board certified in Internal Medicine, Pulmonary Medicine, and Critical Care Medicine. He has received multiple teaching awards and enjoys focusing on medical education.

Research Interests:

Dr. Shah's research interest lies in the field of thermal molecular biology and acute lung injury. In particular, he is interested in lung inflammation, injury, and repair and in particular his focus is on the molecular mechanisms through which febrile-range hyperthermia exerts its immunomodulatory effects on human microvascular endothelial cells in the lung.

Clinical Speciality:

Dr. Shah's clinical and teaching interests have continued to focus on consultative pulmonary medicine as well as fiberoptic bronchoscopy. This includes CT-guided bronchoscopy, transbronchial needle aspiration and endobronchial ultrasound.


M. Longtine, A. McKenzie, D. Demarini, N. Shah, A. Wach, A. Brachat, P. Philippsen, J. Pringle. "Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae." Yeast 1998; 14:953-61.

J. Bahler, J. Wu, M. Longtine, N. Shah, A. McKenzie, A. Steever, P. Philippsen, J. Pringle."Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe." Yeast 1998; 14:943-51.

Nagrasekar, R. Greenberg, N. Shah, I. Singh, J. Hasday. "Febrile-range hyperthermia accelerates caspase-dependent apoptosis in human neutrophils." Journal of Immunology 2008; 181:2636-2643.

N.Shah, M. Tularpurkar, I. Singh, J. Shelhamer, M. Cowan, J. Hasday. "Prostaglandin E2 Potentiates Heat Shock-Induced Heat Shock Protein 72 Expression in A549 Cells." Prostaglandins and Other Lipid Mediators 2010; 93(1-2):1-7.

A. Choi, H. Reynolds et al. "NHLBI Workshop: Respiratory Medicine-Related Research Training for Adult and Pediatric Fellows." Lung 2009; 187:347-366.

H. Sareh, M. Tulapurkar, N. Shah, I. Singh, J. Hasday. "Response of Mice to Continuous 5-day Passive Hyperthermia Resembles Human Heat Acclimation." Cell Stress and Chaperones, 2011; 16(3):297-307.

T. Maity, M. Henry, M. Tulapurkar, N. Shah, J. Hasday, I. Singh. "Distinct, gene-specific effect of heat shock and heat shock factor-1 recruitment and gene expression on CXC chemokine genes." Cytokine 2011; 54:61-7.

Shah NG, Associate Editor in Marcucci L, Martinez EA, Haut ER, Slonim AD, Suarez JI. (eds). Avoiding Common ICU Errors. Wolters Kluwer/Lippincott Williams and Wilkins, Philadelphia, 2007.

I. Singh, N. Shah, E. Almutairy, J. Hasday. "Role of HSF1 in Infectious Diseases." Prokaryotic and Eukaryotic Heat Shock Proteins in Infectious Disease. Springer Publishing, 2009, 4:1-33.