Publications
Chapoval SP, T Neeno, CJ Krco, E Marietta, J Harders, and CS David. HLA-DQ6 and HLA-DQ8 transgenic mice respond to ragweed allergens and recognize distinct set of epitopes on short and giant ragweed group 5 antigens. J. Immunol. 1998. 161: 2032-2037.
Chapoval SP, GH Nabozny, EV Marietta, EL Raymond, CJ Krco, AG Andrews, and CS David. Short ragweed allergen induces eosinophilic lung disease in HLA-DQ transgenic mice. J. Clin. Invest. 1999; 103:1707-1717.
Papouchado BG, SP Chapoval, EV Marietta, CR Weiler, CS David. HLA-DQ/human CD4-restricted immune response to cockroach allergens in transgenic mice. Tissue Antigens. 2000; 55:303-311.
Krco CJ, J Harders, S Chapoval, and CS David. Immune response of HLA-DQ transgenic mice to house dust mite allergen p2: Identification of HLA-DQ restricted minimal epitopes and critical residues. Clin. Immunol. 2000; 97:154-161.
Chapoval SP, EV Marietta, MK Smart, CS David. Requirements for allergen-induced airway inflammation and hyperreactivity in CD4-deficient and CD4-sufficient human leukocyte antigen-DQ transgenic mice. J. Allergy Clin. Immunol. 2001; 108:764-771.
Papouchado BG, SP Chapoval, EV Marietta, CR Weiler, CS David. Cockroach allergen-induced eosinophilic airway inflammation in HLA-DQ/human CD4+ transgenic mice. J. Immunol. 2001; 167: 4627-4634.
Chapoval SP, EV Marietta, MK Smart, K Iijima, AI Chapoval, AG Andrews, and CS David. Allergic inflammatory response to short ragweed extract in HLA-DQ transgenic mice lacking CD4 gene. J. Immunol. 2002; 168:890-899.
Chapoval SP and CS David. CD28 costimulation is critical for experimental allergic asthma in HLA-DQ8 transgenic mice. Clin. Immunol. 2003; 106:83-94.
Chapoval SP and CS David. Identification of antigenic epitopes on human allergens: Studies with HLA transgenic mice. Environ. Health Perspect. 2003; 111:245-250.
Das P, S Chapoval, V Howard, CS David and TE Golde. Immune response against Aï¢1-42 in HLA class II transgenic mice: implications for Aï¢1-42 immune-mediated therapies. Neurobiol. Aging. 2003; 24: 969-976.
Lee CG, SJ Cho, MJ Kang, SP Chapoval, PJ Lee, PW Noble, T Yehualaeshet, B Lu, RA Flavell, J Milbrandt, RJ Homer, JA Elias. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. 2004; J. Exp. Med. 200:377-389.
Lee CG, H Link, P Baluk, RJ Homer, S Chapoval, V Bhandari, MJ Kang, L Cohn, YK Kim, DM McDonald, and JA Elias. Vascular endothelial growth factor (VEGF) induces remodeling and enhances Th2-mediated sensitization and inflammation in the lung. Nature Med. 2004; 10:1095-1103.
Ma B, CG Lee, S Chapoval, W Liu, A Coyle, J Lora, D Picarella, RJ Homer, JA Elias. Role of CCR5 in gamma-interferon-induced and cigarette smoke-induced emphysema. J. Clin. Invest. 2005; 115:3460-3472.
Xue A, SP Chapoval, ES Finn, VR Chowdhary, EV Marietta, TA Gaffey, AC Pursifull, CS David. HLA-DQ8 is a predisposing molecule for detergent enzyme subtilisin BPN-induced hypersensitivity. Clin. Immunol. 2005;117:302-315.
Bhandari V, Choo-Wing R, Chapoval SP, Lee CG, Tang C, Kim YK, Ma B, Baluk P, Lin MI, McDonald DM, Homer RJ, Sessa WC, Elias JA. Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung. Proc Natl Acad Sci U S A. 2006;103:11021-6.
Chapoval SP, A Al-Garawi, JM Lora, I Strickland, B Ma, PJ Lee, RJ Homer, S Ghosh, AJ Coyle, JA Elias. 2007. Inhibition of NF-kB Activation Reduces the Tissue Effects of Transgenic IL-13. J. Immunol. Accepted for publication.