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Raymond T. Jones Ph.D.

Academic Title: Adjunct Professor
Primary Appointment: Pathology
Location: UMH NBW47
Phone: 8-1221
Fax: 8-5508

Personal History:

Old Dominion University, BS, Biology

University of Delaware, MS, Biological Sciences

University of California, Berkeley Post Graduate, Electron Microscopy

University of Maryland, Baltimore, PhD, Pathology

Hanover Medical School, Hanover, Germany, Post-Doc., Experimental Pathology

Research Interests:

Lung and Prostate Cancer

The laboratory is a long standing resource to the Laboratory of Human Carcinogenesis of the National Cancer Institute for the collection and characterization of human cells and tissues from surgical procedures to be utilized for studies of human carcinogenesis and extrapolation of animal data to man. Each cell and tissue has an epidemiological profile on the donor in order to permit case control and other studies of etiology, risk factors, environmental factors and genetic influences. The project has continued with increasing emphasis on case control and molecular epidemiologic questions including human cancer.


Publications selected from 78 peer-reviewed publications

Bennett, W.P., Colby, T.V., Travis, W.D., Borkowski, A., Jones, R.T., Lane, D.P., Metcalf, R.A., Samet, J.M., Takeshima, Y., Gu, J.R., Vähäkangas, K.H., Soini, Y., Pääkö, P., Welsh, J.A., Trump, B.F. and Harris, C.C.: p53 protein accululates frequently in early bronchial neoplasia. Cancer Res. 53: 4817-4822, 1993.

Borkowski, A., Bennett, W.P., Jones, R.T., Borkowski, P., Harris, C.C., Ferreira, L.R., Koa, G.F. and Trump.B.F.: Quantitative image analysis of p53 protein accumulation in keratoacanthomas. Am. J. Dermatopathol. 1: 335-338, 1995.

Greenblatt, M.S., Feitelson, M.A., Zhu, M., Bennett, W.P., Welsh, J.A., Jones, R.T., Borkowski, A. and Harris, C.C.: Integrity of p53 in hepatitis Bx antigen-positive and -negative hepatocellular carcinomas. Cancer Res. 57: 426-432, 1997.

Bennett, W.P., el-Deiry, W.S., Rush, W.L., Guinee, D.G., Jr, Freedman, A.N., Rush, Caporaso, N.E., Welsh, J.A., Jones, R.T., Borkowski, A., Travis, W.D., Fleming, M.V., Trastek, V., Pairolero, P.C., Tazelaar, H.D., Midthun, D., Jett, J.R., Liotta, L.A. and Harris, C.C. p21 walf1/cip1 and transforming growth factor-β1 protein expression correlate with survival in non-small cell lung cancer. Clin. Cancer Res. 4: 1499-1506, 1998.

Ambs, S, Bennett, W.P., Merriam, W.G., Ogunfusika, M.O.,Osner, S.M., Khan, M.A., Jones, R.T., Harris, C.C.: Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53. Br. J. Cancer 78:233-239, 1998.

Krasna, M. J., Mao, Y.S., Sonett, J.R., Tamura, G., Jones, R., Suntharalingam, M., and Meltzer, S.J.: p53 gene protein overexpression predicts results of trimodality therapy in esophageal cancer patients. Ann. Thorac. Surg. 68:2021-2025, 1999.

Albright, C.D., Grimley, P.M.,Jones, R.T., and Reseau, J.H.: Differential effects of TPA and retinoic acid on cell-cell communication in human bronchial cells. Exp. Mol. Path. 72: 62-67, 2002.

Miura, K., Bowman, E.D., Simon, R., Peng, A.C., Robles, A.I., Jones, R.T., Kataghiri, T., He, P., Mizukami, H., Charboneau, L., Kikuchi, T., Liotta, L.A., Nakamura, Y. and Harris, C.C.: Lasser capture microdisection and microarray expression analysis of lung adenocaarcinoma revels tobacco smoking-and prognosis-related molecular profiles. Cancer Res. 62: 3244-3250, 2002.

Zheng, Y.-L., Loffredo, C.A., Yu, Z., Jones, R.T., Krasna, M.., Alberg, A.J., Yung, R., Perlmutter, D., Enewold, L., Harris C.C. and Shields, P.G.: Bleomycin-induced chromosome breaks as a risk marker for lung cancer: a case-control study with population and hospital controls. Carcinogenesis 24:269-274, 2003.

Burke, L., Flieder, D.B., Guinee, D.G., Brambilla, E., Freedman, A.N., Bennett, W.P., Jones, R.T., Borkowski, A, Caporaso, N.A., Fleming, M., Trastek, V., Pairolero, P., Tazelaar, H., Midthun, D., Liotta, L.A., Travis, W.D., and Harris, C.C.: Prognostic Implications of Molecular and Immunohistochemical profiles of the Rb and p53 Cell Cycle Regulatory Pathways in Primary Non-Small Cell Lung Carcinoma. Clinical Cancer Res. 11:232-241, 2005.

Zheng, Y.L., Loffredo, C.A., Alberg, A.J., Yu, Z., Jones, R.T., Perlmutter, D., Enewold, L, Krasna, M.J., Yung, R., Shields, P.G. and Harris, C.C.: Less efficient g2-m checkpoint is associated with an increased risk of lung cancer in African Americans. Cancer Research 65:9566-73, 2005.