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Man E. Charurat
 

Man E. Charurat Ph.D., M.H.S.

Academic Title: Associate Professor
Primary Appointment: Medicine
Secondary Appointments: Epidemiology & Public Health
Additional Title(s): Director, Division of Epidemiology and Prevention, Institute of Human Virology
mcharurat@ihv.umaryland.edu
Location: Institute of Human Virology, 725 W. Lombard Street, Room 449N
Phone: 410-706-1948
Fax: 410-706-1944
 

Personal History:

Man Charurat is an Associate Professor of Medicine and Director of the Division of Epidemiology and Prevention at the Institute of Human Virology. He is an international leader in the field of epidemiological studies of populations at high risk of HIV and AIDS. Dr. Charurat received his Masters of Health Science in Infectious Disease Epidemiology and PhD in International Health from the Johns Hopkins Bloomberg School of Public Health. In 1998, he joined the Institute of Human Virology (IHV), University of Maryland School of Medicine.

Research Interests:

Dr. Charurat's research career began with studies of mother-to-child transmission of HIV, publishing on the ability of highly effective antiretroviral treatment of the mother to eliminate pediatric transmission2 and later documented the adverse consequences of “mixed” feeding of African infant6. Recently, through  NIH R-01 funding, he began investigating HIV exposed uninfected infants and the role of the gut microbiome in developmental delays. His studies involving most at risk populations are at the cutting edge of current global strategies. His work in this arena documented the dynamics of acute HIV infection4 and laid the foundation for subsequent studies that mapped transmission hotspots9 which in turn led to successful NIH R-01 grant funding (TRUST Project) that employ sophisticated recruitment strategies to engage Men having Sex with Men in treatment and prevention services12 and documenting the impact of treatment as prevention.11 Most recently, expanding upon the TRUST study a new NIH RO1 grant (Building TRUST) integrates phylodynamic modeling to pattern incidence and prevalence over time.


Publications:

Dr. Charurat has published over 70 peer-reviewed journal articles. A few of his most highly are listed below:

  1. Cooper ER, Charurat M, Burns D, Blattner WA, and Hoff R. Trends in antiretroviral therapy and mother-to-infant transmission of HIV. JAIDS. 2000 May 1;24:45-47.
  2. Cooper ER, Charurat M, Mofenson L, Hanson C, Pitt J, Diaz C, Hayani K, Handelsman E, Smeriglio V, Blattner WA. Combination antiretroviral strategies for the treatment of pregnant HIV-1infected women and prevention of perinatal HIV-1 transmission. JAIDS. 2002 Apr 15;29:484-494.
  3. Charurat M, Blattner W, Hershow R, Buck A, Zorilla C, Watts H, Paul M, Landesman S, Hay C, Smeriglio V, Adeniyi-Jones S, Tuomala R. Changing trends in clinical AIDS presentations and survival among human immunodeficiency virus infected women. J Womens Health. 2004;13(6):719-30.
  4. Blattner WA, Oursler KA, Cleghorn FR, Charurat M, Sill A, Bartholomew C, et al. Rapid viral clearance following acute HIV-1 infection: Correlates of AIDS risk. J Infect Dis.  2004 May 15;189(10):1793-801.
  5. Devico A, Fouts T, Lewis GK, Gallo RC, Godfrey K, Charurat M, Harris I, Galmin L, Pal R. Antibodies to CD4-induced sites in HIV gp120 correlate with the control of SHIV challenge in macaques vaccinated with subunit immunogens. Proc Natl Acad Sci USA. 2007 Oct 30;104(44):17477-82.
  6. Maru S, Datong P, Selleng D, Mang E, Inyang B, Ajene A, Guyit R, Charurat M, Abimiku A. Social determinants of mixed feeding behavior among HIV-infected mothers in Jos, Nigeria. AIDS Care. 2009 Sep;21(9):1114-23.
  7. Charurat M, Oyegunle M, Benjamin R, Habib A, Eze E, Ele P, Ibanga I, Ajayi S, Eng M, Mondal P, Gebi U, Iwu E, Etiebet MA, Abimiku A, Dakum P, Farley J, Blattner W. Patient retention and adherence to antiretrovirals in a large antiretroviral therapy program in Nigeria: a longitudinal analysis for risk factors. PLoS One. 2010 May 11;5(5):e10584
  8. Ahmed S, Delaney K, Villalba-Diebold P, Aliyu G, Constantine N, Ememabelem M, Vertefeuille J, Blattner W, Nasidi A, Charurat M. HIV counseling and testing and access-to-care needs of populations most-at-risk for HIV in Nigeria. AIDS Care. 2013;25(1):85-94. Epub 2012 Jul 10.
  9. Charurat M, Nasidi A, Delaney K, Saidu A, Croxton T, Eyzaguirre L, Mondal P, Aliyu G, Constantine N, Abimiku A, Carr JK, Vertefeuille J, Blattner WA. Characterization of acute HIV-1 infection in high-risk Nigerian populations. J Infect Dis.2012 Apr 15;205(8):1239-47.
  10. Omoni A, Christian P, Sadoh W, Okechukwu A, Olateju E, Omoigberale A, Blattner W, Charurat M. Immunologic outcomes of antiretroviral therapy among HIV-infected Nigerian children and its association with early infant feeding and nutritional status at treatment initiation. Ped Infect Dis J. 2013 Jul;23(7):e291-7.
  11. Charurat M, Emmanuel B, Akolo CA, Baral S, Ake J, Kennedy S, Emmanuel B, Orazulike I, Boulay M, Keshinro B, Blattner W. Uptake of Treatment as Prevention and continuum of care among Men who have sex with men in Nigeria. J Acquir Immune Defic Syndr. 2015 Mar 1;68 Suppl 2:S114-23.
  12. Baral S, Schwartz S, Orazulike I, Ketende S, Ugoh K, Peel S, Ake J, Blattner W, Charurat M. Evaluating Respondent Driven Sampling for Recruiting MSM into HIV Prevention Study.  J Acquir Immune Defic Syndr. 2015 Mar 1; 68 Suppl 2:S107-13.
  13. Coker M, Etibet M, Chang H, Gambo A, Jumare J, Babashani M, Dakum P, Charurat M, Blattner W, Eng M, Ndembi N. Socio-demographic and adherence factors associated with viral load suppression in HIV-infected adults initiating therapy in northern Nigeria: A randomized controlled trial of a peer support intervention. Curr HIV Res.  Feb 2015;13(4):279-85.
  14. Omoni A, Christian P, Sadoh W, Okechukwu A, Olateju E, Omoigherale A, Blattner W, Charurat M. Early infant feeding, growth and nutritional status of HIV-infected Nigeria preschool children receiving antirretroviral treatment. J Nutr. 2015. Accepted, July 14, 2015. Letter of provisional acceptance enclosed.
  15. Schwartz SR, Nowak RG, Orazulike I, Keshinro B, Ake J, Kennedy S, Njoku O, Blattner WA, Charurat M, Baral SD; TRUST Study Group. The immediate effect of the Same-Sex Marriage Prohibition Act on stigma, discrimination, and engagement on HIV prevention and treatment services in men who have sex with men in Nigeria: analysis of prospective data from the TRUST cohort. Lancet HIV. 2015 Jul 1;2(7): e299-e306. [Co-senior author].