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Lawrence W. Adler

Lawrence W. Adler M.D.

Academic Title: Clinical Assistant Professor
Primary Appointment: Psychiatry
Location: 22 S. Greene St., S12A08
Phone: (410) 328-6637
Phone: (443) 621-6733
Fax: (410) 328-2672

Personal History:


  • B.S., 9/67-6/71, University of Maryland, College Park, Biochemistry
  • M.D., 9/71-12/75, University of Maryland School of Medicine
  • Certificate of Graduate Studies, 2007, Business of Medicine, Carey Business School, Johns Hopkins University

Post Graduate Education and Training

  • Post-doctoral Research Associate, 12/75-7/76, University of Maryland School of Medicine, Dept. of Biological Chemistry
  • Residency in Psychiatry, 7/76-6/79, Sheppard-Pratt Hospital


  • Psychiatry, American Board of Psychiatry and Neurology, 1983, #25039
  • Geriatric Psychiatry, American Board of Psychiatry and Neurology, April 1991-December 2001, December 2001-December 2011, April 2011-April 2021 #004
  • Clinical Psychopharmacology, American Society of Clinical Psychopharmacology,November 1998-May 2009
  • Certified Physician Investigator, Association of Pharmaceutical Physicians and Investigators, November 2002-ongoing

Research Interests:

  • Clinical psychopharmacology
  • Clinical research
  • Public Health
  • Epidemiology and genetics of psychiatric illness

Clinical Speciality:

  • Clinical psyschopharmacology
  • Geriatric psychiatry


Peer-Reviewed Journals

Rosen BP, Adler LW. The Maintenance of the Energized Membrane State and its Relation to Active Transport in E. Coli. Biochim Biophysicia Acta, 387 (1975) 23.

Adler LW, Rosen BP. Properties of E. Coli Mutants with Alterations in Mg-Adenosine Triphosphatase., Journal of Bacteriology, 28 (1976) 248-25.

Adler LW, Rosen BP#. Functional Mosaicism of Membrane Proteins in Vesicles of E. Coli. Journal of Bacteriology, 129 (1979) 15-27.

Adler, LW, Rosen, BP# , Hasan, SM, Tchikawa T. Orientation of the Protonmotive Force in Membrane Vesicles of E. Coli. Journal of Supramolecular Structure, 7 (1977) 15-27.

Adler LW. Mixed Bipolar Disorder Responsive to Lithium and Clonazepam. Journal of Clinical Psychiatry, 47 (1986) 49-50.

Pulver AE, Carpenter WT#, Adler LW, McGrath, J. Accuracy of the Diagnosis of Affective Disorders and Schizophrenia in Public Hospitals. American Journal of Psychiatry 1988 Feb; 145 (2) 218-220.

Pulver AE, Brown CH. Wolyniec P, McGrath J, Adler, L, Carpenter WT, Childs B; Schizophrenia: Age at Onset, Gender, and Familial Risk. Acta Psychiatrica Scand 1990, Nov.82 (5) 344-5.

Pulver AE, Liang KY, Brown CH, Wolyniec P, McGrath, J, Adler, L, Tam D, Carpenter WT, Childs B. Risk Factors in Schizophrenia: Season of Birth, Gender, and Familial Risk. British J. Psychiatry 1992 Jan; 160: 65-71.

Pulver AE, Liang KY, Wolyniec PS, McGrath J, Melton BA, Adler L, Childs B. Season of Birth of Siblings of Schizophrenic Patients. British J. Psychiatry 1992 Jan; 160: 71-75.

Pulver AE, Karayioorgou M, Wolyniec PS, Lasseter VK, Kasch L, Nestadt G, Antonarkis S, Housman D, Kazazian HH, Myers D, Adler L, Carpenter WT. Sequential Strategy to Identify a Susceptibility Gene for Schizophrenia: Report of Potential Linkage on Chromosome 22q12-q13.1 Part 1 American Journal of Medical Genetics, 1994 March; 54: 36-43.

Klein DF, Thase ME, Endicott J, Adler L., Glick I., Kalali A., Leventer S., Mattes J., Ross P., Bystristsky A. Improving Clinical Trials: American Society of Clinical Psychopharmacology Recommendations. Archives of General Psychiatry, 2002 March; 59(3): 272-8.

Hertzman M, Adler LW, Arlen B, Kern M. Lisinopril May Augment Antidepressant Response. Journal of Clinical Psychopharmacology, Journal of Clinical Psychopharmacology, 25(2005) 618-620.

Keefe RSE, Bilder RM, Harvey PD, Davis SM, Palmer BW, Gold JM, Meltzer HY, Green MF, Miller DD, Canive JM, Adler LW, Mansschreck TC, Swartz M, Rosenheck R, Perkins DO, Walker TM, Stroup TS, McEvoy JP, Lieberman JA. Baseline Neurocognitive Deficits in the CATIE Schizophrenia Trial. Neuropsychopharmacology, advanced online publication 19 April 2006, 1-14.

Adler LW, Regenold WT. Valproate-related hyperammonemia in older adult psychiatric inpatients, The Primary Companion to CNS Disorders, 2015 April; 17(2):doi:10.4088/PCC14101737.

Books and Book Chapters

Hertzman M & Adler LW (2010) Clinical Trials in Psychopharmacology: A Better Brain 2nd edn. Wiley Press. West Sussex.

Adler LW (2010) "Genes, The Genome and Brain Tailored Drugs"; In: Hertzman M & Adler LW (2010) Clinical Trials in Psychopharmacology: A Better Brain 2nd edn. Wiley Press. West Sussex pp.43-56.


Adler, L.W. Alzheimer's Disease Prevention: Is Lithium Neuroprotective? Paper presented at American Association of Geriatric Psychiatry Annual Meeting, San Diego, CA, 2005.

Adler, LW.#, Zepp, H, Cerro, L. A Model for Integrating Clinical Trials in a Community Practice Setting. Presented at APA Institute for Psychiatric Services, San Diego, CA, 2005.

Adler, L.W. Alzheimer's Disease: A Final Common Pathway for Genetic Risk, Vascular Risk, Mood Dysregulation and Energy Dysregulation. Presented at American Association of Geriatric Psychiatry Annual Meeting, Puerto Rico, 2006.

Adler, L.W.#, Cerro L,and Zepp H. A Meta-Analysis of the Efficacy of Paroxetine vs. Placebo Utilizing the GlaxoSmithKline Clinical Trials Registry. Presented at APA Annual Meeting, Toronto,CA, 2006

Adler, L.W.#, Remission of Major Depressive Episodes on Paroxetine vs. Placebo in Elderly and Adult Subjects. Presented at American Association of Geriatric Psychiatry Annual Meeting, New Orleans, LA, 2007.

Adler, L.W.#, Reducing the Medical and Financial Burden of Depressive Illness: A Plan for Improving Health Care Services. Presented at the American Psychiatric Association Annual Meeting, San Diego, CA, 2007.

Adler L.W., Regenold WT, Lachner C, Martin C, John D, Nakkalupu S. Valproate-Related Hyperammonemiain Older Psychiatric Inpatients. Presented at the American Association of Geriatric Psychiatry, Orlando, FL, 2013.

Adler L, Regenold WT, Doddi S. A catatonia model as dysregulated glutamatergic cortico-thalamo-cortico neurotransmission. Presented at CINP (International College of Neuropsychopharmacology) World Congress, Vancouver, Canada, June 2014.

Adler L. Identical twins with discordant neuropsychiatric illnesses. Presented at Annual Meeting of American Neuropsychiatric  Association (ANPA), Orlando, FL, March 2015.