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Laura M Rowland Ph.D.

Academic Title: Associate Professor
Primary Appointment: Psychiatry
lrowland@mprc.umaryland.edu
Location: MPRC, Neuroimaging Research Program, Tawes Bld
Phone: (410) 402-6803

Personal History:

Ph.D. Experimental Psychology, University of New Mexico 2003

Research Interests:

  • Schizophrenia
  • Learning and memory
  • Proton Magnetic Resonance Spectroscopy (1H-MRS)
  • Functional Magnetic Resonance Imaging (fMRI)

Publications:

Bustillo JR, Lauriello J, Rowland LM, Thomson LM, Petropoulos H, Hammond R, Hart B, Brooks WM. Longitudinal follow-up of neurochemical changes during the first year of antipsychotic treatment in schizophrenia patients with minimal previous medication exposure. Schizophr Res. 2002 Dec 1;58 (2-3):313-21. PMID: 12409172

Villarreal G, Petropoulos H, Hamilton DA, Rowland LM, Horan WP, Griego JA, Moreshead M, Hart BL, Brooks WM. Proton magnetic resonance spectroscopy of the hippocampus and occipital white matter in PTSD: preliminary results. Can J Psychiatry. 2002 Sep;47 (7):666-70. PMID: 12355679

Villarreal G, Hamilton DA, Petropoulos H, Driscoll I, Rowland LM, Griego JA, Kodituwakku PW, Hart BL, Escalona R, Brooks WM. Reduced hippocampal volume and total white matter volume in posttraumatic stress disorder. Biol Psychiatry. 2002 Jul 15;52(2):119-25. PMID: 12114003

Bustillo JR, Rowland LM, Lauriello J, Petropoulos H, Hammond R, Hart B, Brooks WM. High choline concentrations in the caudate nucleus in antipsychotic-naive patients with schizophrenia. Am J Psychiatry. 2002 Jan;159(1):130-3. PMID: 11772701

Mullins PG, Rowland LM, Jung RE, Sibbitt W. A novel technique to study the brain's response to pain: proton magnetic resonance spectroscopy. NeuroImage. 2005 26: 642-646. PMID: 15907322

Rowland LM, Bustillo JR, Mullins PG, Jung RE, Lenroot R, Landgraf E, Barrow R, Yeo R, Lauriello J, Brooks WM. Effects of ketamine on anterior cingulate glutamate metabolism in healthy humans: a 4-T proton MRS study. Am J Psychiatry. 2005 Feb;162(2):394-6. PMID: 15677610

Rowland LM, Astur RS, Jung RE, Bustillo JR, Lauriello J, Yeo RA. Selective cognitive impairments associated with NMDA receptor blockade in humans. Neuropsychopharmacology. 2005 Mar;30(3):633-9. PMID: 15647751

Rowland LM. Subanesthetic ketamine: How it alters physiology and behavior in humans. Aviat Space Environ Med, 2005 76: 52-58. PMID: 16018330

Jung RE, Haier RJ, Yeo RA, Rowland LM, Petropoulos H, Levine AS, Sibbitt WL, Brooks WM. Sex Differences in N-acetylaspartate Correlates of General Intelligence: A 1H-MRS Study of Normal Human Brain. NeuroImage. 2005 26: 965-972. PMID: 15955507

Theberge J, Rowland LM, Jensen JE. Regarding “Increased Prefrontal and Hippocampal Glutamate Concentration in Schizophrenia: Evidence from a Magnetic Resonance Spectroscopy Study”, Biological Psychiatry. 2007 61: 1218-1219. PMID: 16950227

Rowland LM, Shadmehr R, Kravitz D, Holcomb HH. Sequential Neural Changes During Motor Skill Learning in Schizophrenia, Psychiatric Research: Neuroimaging. 2008, 163(1):1-12. PMID: 18407471

Bustillo JR, Rowland LM, Jung RE, Brooks WM, Qualls C, Hammond R, Hart B, Lauriello J. Proton Magnetic Resonance Spectroscopy During Initial Treatment with Antipsychotic Medication in Schizophrenia, Neuropsychopharmacology. 2008, 33, 2456–2466. PMID: 18094668

Rowland LM, Spieker EA, Barker PB, Francis A, Carpenter WT, Buchanan RW. White matter alterations in deficit schizophrenia, Neuropsychopharmacology. 2009 May;34(6):1514-22. PMID: 19052539

Rowland LM, Spieker EA, Holcomb HH. A review of diffusion tensor imaging in schizophrenia, Clinical Schizophrenia & Related Psychoses, 3 (3): 142-154.

Bustillo JR, Rowland LM, Mullins P, Jung R, Chen H, Qualls C, Hammond R, Brooks WM, Lauriello J.  (2010). 1H-MRS at 4 Tesla in Minimally Treated Early Schizophrenia, Molecular Psychiatry, 15(6):629-36

Rowland LM, Griego JA, Spieker EA, Cortes CR, Holcomb HH. (2010). Neural changes associated with relational learning in schizophrenia, Schizophrenia Bulletin, 36(3):496-503.

Rowland LM, Beason-Held L, Tamminga C, Holcomb HH. (2010). The Interactive Effects of Ketamine and Nicotine on Cerebral Blood Flow, Psychopharmacology, 208(4):575-84

Spieker EA, Astur RS, West J, Griego JA, Rowland LM. Spatial Memory Deficits in a Virtual Reality Eight-Arm Radial Maze in Schizophrenia, Schizophrenia Research, 135(1-3):84-9

Rowland LM, Kontson K, West J, Edden RA, Zhu H, Wijtenburg SA, Holcomb HH, Barker PB.  In vivo measurements of glutamate, GABA, and NAAG in schizophrenia, Schizophrenia Bulletin, In press

Rowland LM, Edden RA, Zhu H, Barker PB, Hong LE. GABA predicts inhibition of frequency-specific oscillations in schizophrenia, Journal of Neuropsychiatry and clinical neurosciences, In press

S. A. Wijtenburg, L.M. Rowland, R.A.E. Edden, P.B. Barker.  Reproducibility of Brain Spectroscopy at 7T using Conventional Localization and Spectral Editing Techniques, Journal of Magnetic Resonance Imaging Journal of Magnetic Resonance Imaging, In press