Karen L Kotloff
 

Karen L Kotloff M.D.
Academic Title: Professor
Primary Appointment: Pediatrics
Secondary Appointments: Medicine
KKOTLOFF@medicine.umaryland.edu
Location: HSF1, Room 480
Phone: (410) 706-5328
Fax: (410) 706-6205

Research Interests

Dr. Kotloff is a lead investigator at the Vaccine and Treatment Evaluation Unit VTEU in the Center for Vaccine Development at the University of Maryland School of Medicine, which is leading one of the nation’s first studies of an experimental vaccine designed to prevent the 2009 H1N1 influenza virus (see news release).

Dr. Kotloff also conducts Phase 1 and 2 clinical trials in adults of vaccines for the prevention of Shigella, group A streptococcus, Helicobacter pylori and other infectious diseases. She also runs clinical trials of pediatric vaccines. She has conducted several large epidemiologic studies to study infantile diarrhea and sexually transmitted diseases (including HIV) among college students. She has recently begun designing studies of the epidemiology of group A streptococcus, diarrheal diseases and several vaccine-preventable infections in Bamako, Mali, in collaboration with local researchers at CVD - Mali.

Publications

Tapia M., Sow S., Medina-Moreno S., Lim Y., Pasetti M., Kotloff K., Levine M.M. A serosurvey to identify the "window of vulnerability" to wild type measles among infants in rural Mali. Am J Trop Med Hyg 2005;73:26-31.

Sow S., Diallo S., Campbell J., Tapia M., Keita T., Keita M.M., Murray P., Kotloff K., Levine M.M. Burden of invasive disease caused by Haemophilus influenzae type b in Bamako, Mali: impetus for routine infant immunization with conjugate vaccine. Pediatr Infect Dis J 2005;24:533-7.

Kotloff K.L., Wasserman S.S., Jones K.F., Livio S., Hruby D.E., Franke C.A., Fischetti V.A. Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcal vaccine. Infect Immun 2005;73:2360-6.

Lee H., Kotloff K., Chukaserm P., Samosornsuk S., Chompook P., Deen J.L., von Seidlein L., Clemens J.D., Wanpen C. Shigellosis remains an important problem in children less than 5 years of age in Thailand. Epidemiol Infect 2005;133:469-74.



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