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Ellis S. Caplan M.D.

Academic Title: Clinical Professor
Primary Appointment: Medicine
Location: STC, T3R52
Phone: (410) 328-3656
Fax: (410) 328-6826

Personal History:


1964: B.S., University of Maryland, College Park, Maryland

1968: M.D., University of Maryland School of Medicine, Baltimore, Maryland


1968 - 1969: Medical Internship, University of Maryland Hospital, Baltimore, Maryland

1969 - 1970: Medical Residency, Sinai Hospital of Baltimore, Baltimore, Maryland

1970 - 1971: Medical Residency, University of Maryland Hospital, Baltimore, Maryland

1973 - 1975: Infectious Diseases Fellowship, University of Maryland Hospital, Baltimore, Maryland


1971 – 1973: 67th Evacuation Hospital, Internist, Qui Nhon, Vietnam; Third Field Hospital, Chief of Medicine,
Saigon, Vietnam; Fort Carson Hospital, Internist, Colorado Springs, Colorado


1973 - 1975: Instructor in Medicine; University of Maryland School of Medicine

1975 - 1979: Assistant Professor of Medicine, University of Maryland School of Medicine

1979 - 1984: Clinical Associate Professor of Medicine, University of Maryland School of Medicine

1984 - 2005: Associate Professor of Medicine, tenured, University of Maryland School of Medicine

2005 - 2007: Clinical Associate Professor of Medicine, part-time, University of Maryland School of Medicine

2007 - present: Clinical Professor of Medicine, University of Maryland School of Medicine


Refereed Journal Articles

Caplan ES., and Kluge R.: Gas Gangrene: Review of 34 Cases. Archives of Internal Medicine. 136: 288-291, 1976. 

Richman DD., Murphy BM., Chancok RM., Gwaltney JM., Jr., Douglas RG., Betts RF., Blacklow NR., Rose RB., Parrino TA., Levine MM., and Caplan ES.: Temperature-Sensitive Mutants of Influenzae A Virus Xll Safety Antigenicity, Transmissibility, and Efficacy of Influenza A/Udorn/72-ts-l (E) Recombinant Viruses in Human Adults  Journal of Infectious Diseases. 134: 585-594, 1976.

Caplan ES., Hughes TP., Donnell S., Levine M., Hornick RB.: Evaluation of the Reactogenicity and Immunogenicity of Parenteral Monovalent/Victoria (H3N2) Influenza Vaccine in Healthy Adults.  Journal of Infectious Disease 136:  (Supplement) S484-490, 1977.

Levine MM., Caplan ES., Waterman DH., Cash RA., Hornick RB., Snyder MJ.: Diarrhea caused by Escherichia coli that produce only Heat-Stable Enterotoxin.  Infection and Immunity, 17: 78-82, 1977.

Dolin R., Murphy BR., and Caplan ES.: Lymphocyte Blastogenic Responses to Influenza Virus Antigens After Influenza and Vaccination in Man.  Infection and Immunity, 19: 867-874, 1977.

Caplan ES., Hoyt NJ., Cowley R. Changing Patterns of Nosocomial Infection in Severely Traumatized Patients. American Surgeon, 45: 204-210, 1979.

Weinblatt ME., and Caplan ES.: Fatal Mycoplasma Encephalitis in an Adult. Archives of Neurology, 37: 321, 1980.

Walrath JM., Abbott NK, Caplan ES., Scanlan E.: Stopcock:  Bacterial Contamination in Invasive Monitoring Systems.  Heart and Lung, 8: 100-104, 1979.

Applefeld J., and Caplan ES.: A Case of Water Hemlock-Cicuta Maculta Poisoning.  Journal of the American Medical Association, 8: 401-405, 1979

Richman RC., Pons VG., Murphy BR., Caplan ES., and Dolin R.: Cell- Medicated Cytotoxicity Following Influenza Infection and Vaccination in Humans.  Journal of Medical Virology, 4: 1-14, 1979.

Murillo J., Standiford HC., Tate BA., Caplan ES., and Calia FM.: Parenteral Prophylaxis Against Enterococcal Endocarditis.  American Journal of Medical Science, 277: 195-200, 1979.

Majerus TC., and Caplan ES: Predicting Serum Gentamicin Levels in Adult Trauma Patients. Clinical Therapeutics, 3: 316-28, 1980.

Saah AJ., Drusano GL., Warren JW., Tenney JH., and Caplan ES.: Cefoxitin Resistant Aerobic Gram Negative Bacilli in Infections Associated with the Gastrointestinal Tract.  Annals of Internal Medicine, 94: 487-488, 1981.

Standiford HC., Berstein D., Nipper HC., Caplan ES., Tatem B., Hall JS., and Reynolds J.: Latex Agglutination Inhibition Card Test for Gentamicin Assay:  Clinical Evaluation and Comparison with Radioimmunoassay and Bioassay.  Antimicrobial Agents and Chemotherapy, 19: 620-624, 1981.

Caplan ES., Hoyt N.: Infection Surveillance and Control in the Severely Traumatized Patient. The American Journal of Medicine, 70: 638-640, 1981.

Soderstrom CA., Wasserman DH., Dunham CM., Caplan ES., Cowley RA.: The Superiority of the Femoral Artery for Monitoring:  A Prospective Study.  American Journal of Surgery, 144: 309-312, 1981.

Drusano GL., Warren JW., Saah AJ., Caplan ES., Tenney JH., Hansen S., Granados J., Standiford HC., and Miller EH., Jr.: Cefoxitin vs.  Clindamycin/Aminoglycoside in Mixed Anaerobic/Aerobic Infections:  A Prospective Randomized Controlled Trial.  Surgery, Gynecology, and Obstetrics, 154: 715-720, 1982.

Finley RS., Fortner CL., deJongh CA., Wade JC., Newman K., Caplan ES., Britten J., Wiernik PH., Schimpff SC.: A Comparison of Standard vs.  Pharmacokinetically Adjusted Amikacin Dosing in Granulocytopenic Cancer Patients.  Antimicrobial Agents and Chemotherapy, 22: 193-197,  1982.

Caplan ES., and Hoyt NJ.: Nosocomial Sinusitis.  Journal of American Medical Association, 247: 639-641, 1982.

Caplan ES., Boltanksy H., Rooney J., Snyder MJ., Hoyt N., Schiffman G., Cowley RA.: Responsiveness of Severely Traumatized Splenectomized Patients to Immediate Vaccination with Polyvalent Pneumococcal Vaccine.  Journal of Trauma, 23 (9): 801-805, 1983.

Warren JW., Miller EH., Jr., Difranco DE., Tenney JH., Caplan ES., and Anthony WC.: A Randomized Controlled Trial of Cefoperazone vs. Cefamandole/Tobramycin for the Empiric Treatment of Serious Gram -Negative Infections.  Reviews of Infectious Diseases, 5: S173-S180, 1983.

Soderstrom CA., Caplan ES.: Infected False Femoral Artery Aneurysm.  The Journal of Cardiovascular Surgery, 24: 63-68, 1983.

Miller EH., Caplan ES.: Nosocomial Hemophilus Pneumonia in Severely Traumatized Patient.  Surgery, Gynecology and Obstetrics, 159: 153-156, 1984.

Phillips RA., Valente WA., Caplan ES., Connor TB., Wisewell JG.: Circulating Thyroid Hormone Changes in Acute Trauma: Prognostic Implications for Clinical Outcome.  Journal of Trauma. 24 (2):  116-119, 1984.

Drusano GL., Forrest A., Fiore D., Auger F., and Caplan ES.: Effect of Saturable Clearance During High-Dose Mezlocillin Therapy.  Antimicrobial Agents and Chemotherapy, Vol. 26, No. 5: 686-688, 1984.

Caplan ES., Hoyt NJ., Rodriguez A., Cowley RA.: Empyema Occurring in the Multiply Traumatized Patient.  Journal of Trauma 24 (9): 785-789, 1984.

Caplan ES. and Hoyt NJ.: Identification and Treatment of Infections in the Multiply Traumatized Patient.  American Journal of Medicine, 79 (lA):  68-76, 1985.

Khabbaz RF., Standiford HC., Bernstein D., Nipper HC., Tatem BA., Smalls U., Drusano G., Caplan, ES.: Measurement of Amikacin in Serum by a Latex Agglutination Inhibition Test.  J. Clinical Microbiology, November: 699-701, 1985.

Walsh T., Myers R., Troop B., Belzberg H., Caplan, ES.: Lemierre's postanginal septicemia.  Problems of diagnosis and management in the antibiotic era.  Infections in Surgery, 4 (5): 383-396, 1985.

Joshi M., Anthony WC., Tenney JH., Drusano GL., Caplan ES., Standiford H.C., Henson A., Warren JW.,: "Double Blinded, Prospective, Multicenter Trial Comparing Ceftazidime with Moxalactam in the Treatment of Serious Gram- Negative Infections".  Antimicrobial Agents and Chemotherapy, 30 (1):  90-95, 1986.

Joshi M., Fitzpatrick BJ., Warren JW., Caplan ES., and Tenney JH.: A Randomized Controlled Trial of Moxalactam Versus Clindamycin/Tobramycin in the Treatment of Mixed Anaerobic/Aerobic Infections.  The American Surgeon, 52 (8): 467-471, 1986.

Perlman D., and Caplan ES.: Nosocomial Sinusitis: A New and Complex Threat.  The Journal of Critical Illness, 2 (5): 19-25, 1987.

Dellinger EP, Caplan ES., Weaver L.D.: Duration of Preventive Antibiotic Administration for Open Extremity Fractures.  Archives of Surgery, 123:  333-339, 1988.

Caplan ES.: Role of Immunomodulator Therapy in Sepsis.  Am. J. Surg. 165, Suppl. 20S-25S, 1993.

Caplan ES., Preas MA., Soderstrom CA., Bosse M., Hendrix L., Caplan ML., Bansal  J., Constantine NT.  Seroprevalence of HIV, HBV, HCV and RPR in a Trauma Population.  Journal of Trauma, 39 (3):  533-538, 1995.

Lacson EK, Al-Makki A, Caplan ES, Zigel C.  An unexpected clue:  the peripheral blood smear in a patient with AIDS. Maryland Medical Journal, 45(6):  482-484, 1996.

Bochicchio, GV, Joshi M, Knorr K, Caplan E, Scalea T.  Impact of Community-Acquired Infection on Acquisition of Nosocomial Infection, Length of Stay, and Mortality in Adult Blunt Trauma Trauma.  Surgical Infections 3 (1): 2128, 2002.

Bochicchio G, Joshi M, Caplan E, Scalea T.  Incidence and Microbiology of Nosocomial Infections in the Geriatric Trauma Population .  Infections in Medicine, 19: 512-516. 2002.

Book Chapters

Caplan ES.  Antimicrobial Therapy in the Traumatized Patient.  In:  Antimicrobial Therapy, Third Edition, Kagan M., ed, W. B. Saunders, 35: 370-¬376, 1980.

Schimpff SC., Caplan ES., deJongh C.: Infections in the Critical Care Patient.  In: Principles and Practice of Critical Care Medicine.  Thompson L, ed.  W. B. Saunders, 505-517, 1982.

Caplan, ES.: Infection Control and Management.  In: Shock Trauma in Critical Care Manual.  Cowley R Adams, Dunham M., eds. University Park Press, 26: 401-430, 1982.

Walsh TJ., Caplan ES.: Use of Antibiotics in the Traumatized and Critically Ill Patient.  In: Critical Problems in Trauma.  J.P. Lippincott Publishers, 3 (11), 1983. 

Caplan ES., and Hoyt NJ.: Infection Control in Neonatal and Adult Intensive Care Units In:  The Therapy and Practice of Infection Control.  Praeger Publishers, 11: 130-155, 1984.

Caplan ES., Kotloff K.: The Trauma Patient.  In: The Patient at Risk for Infection. James E. Pennington, (consulting editor), Smith Kline and French.  27-63, 1986.

Joshi M., Caplan E.: Infectious Diseases.  In:  Respiratory Management of Critically Ill Patients. Applefeld J, and Lindberg S., eds., Blackwell Scientific Publications, Inc., 73-105, 1988.

Caplan ES.  The Principles of Antibiotic Therapy in Critical Illness.  In:  TRAUMA Emergency Surgery and Critical Care.  Siegal J, ed.  Churchill Livingston, Inc., 16: 503-542, 1987.

Caplan ES.: Antibiotic Use in the Multiply Traumatized Patient:  In:  The Pathophysiology of Combined Injury and Trauma. Gruber D, Walker RL, MacVittie TJ, Conklin JJ, eds., Academic Press, Inc., 127-146, 1987. 

Stillwell M., and Caplan ES.: The Septic Multiple Trauma Patient.  In: Critical Care Clinics of North America.  W.B. Saunders Company, 4 (2): 345-373, 1988.

Stillwell M, and Caplan, ES:  The Septic Multiple Trauma Patient. (Special Article)  In: Infectious Disease Clinics of North America. Drutz, D., ed., W.B. Saunders,  3 (1): 155-183, 1989.

Schimpff SC DeJongh CA., and Caplan ES: Infections in the Critical Care Patient.  In: Principles and Practice of Critical Care Medicine.  Thompson L, ed.  W.B. Saunders, 767-780, 1989.
Gitterman S., and Caplan, ES.:  Infection in Thoracic Trauma.  In: Management of Cardiothoracic Trauma. Turney, Rodrigquez, Cowley, eds.,  Williams and Wilkins, 7: 123-146, 1990.

Whittle D., and Caplan ES.:  Infections in the Multitrauma Patient.  In:  Principles and Practice of Medical Intensive Care.  Carlson RW, Geheb MA, eds., W.B. Saunders Company, 47: 556-566, 1993.

Rapoport, M and Caplan ES:  Tularemia.  In: Conn's Current Diagnosis (8), Sanders, ed., W. B. Saunders, 179-181, 1991.

Fiore AE, Joshi M. and Caplan ES.:  Approach to Infections in the Multiply Traumatized Patient. In: Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases, Mandell, Bennett, Dolin, Eds., Churchill Livingstone, Inc., 297: 2756-2765, 1995.

Hirsh E., Joshi M., and Caplan ES.:   Infectious Complications in Trauma Patients. In: Complications in Trauma and Critical Care.  Maull, Rodriguez, Willis, Eds., W. Saunders Company, 3: 20 -29, 1996.

Caplan, ES.: Fever Following Surgery and Nonsurgical Trauma. In:  Fever: Basic Mechanisms and Management.  Mackowiak, P., Ed., Raven Press, 28: 375-382, 1996.

Rabinowitz, P and Caplan ES.:  Management of Infections in the Trauma Patient.  In: Surgical Clinics of North America. Rodriguez, Maull, Feliciano, Eds., W.B. Saunders Company, 79 (6): 1373-1383, 1999.

Rabinowitz R, Fiore, A. Joshi M., and Caplan, ES: Approach to Infections in the Multiply Traumatized Patient. In: Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases,  Mandell, Bennett, Dolin, Eds., Churchill Livingstone, Inc., 309: 3191-3197, 2000.

Mulinde,  J and Caplan, ES: Hyperbaric Oxygen.  In: Mandell, Douglas, and Bennett’s  Principles and Practice of Infectious Diseases, Mandell, Bennett, Dolin, Eds.,  Churchill Livingstone, Inc., 38: 501-505, 2000.

Rabinowitz, R, Mulinde, J, and Caplan, ES: Hyperbaric Oxygen. In: Mandell, Douglas, and Bennett’s of Principles and Practice of Infectious Diseases, Mandell, Bennett, Dolin, Eds.,  Churchill Livingstone, Inc., 40: 563-568, 2005. ( in publication, updated 2010)

Stein, D, Rabinowitz, R, Caplan, E:  Trauma. In: Hospital Medicine, 2nd Edition, Goldman L., Wachter, R., Hollander H., eds., Lippincott Williams and Wilkins, 34, 287-294, 2005.