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Stephen G Reich
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Stephen G Reich M.D.

Academic Title: Professor
Primary Appointment: Neurology
sreich@som.umaryland.edu
Location: UMMC, N4W46
Phone: (410) 328-2164
Fax: (410) 328-0167

Personal History:

Education

University of Kansas, 1975-1976

Tulane University, 1976-1979, B.S. Mathematics and B.A. Latin American Studies (with honors)

Tulane University School of Medicine, 1979-1983, M.D.

Post-Graduate Training

Mt. Sinai Hospital, Cleveland, Ohio, 1983-1984, Internship in Internal Medicine

Case Western Reserve/University Hospitals of Cleveland, Ohio, 1984-1987, Resident in Neurology (under Dr. Robert Daroff)

The Johns Hopkins Hospital, July 1987-June 1988, Fellow - Movement Disorders (under Dr. Mahlon DeLong)

Research Interests:

Movement disorders


Current Grant Support:

Site Principal Investigator [2006-] Genetic and Environmental Risk Factors for PSP. 1RO1AG024040-01A2  NIH/NINDS (Dr. Irene Litvan, PI)  [Total award requested: $3,416,007(final budget pending including individual site awards)]

Principal Investigator [2006-]: GE Healthcare. An Open Label, Phase II Study to Assess the Safety and Efficacy of Technetium (99mTc) NC100697 Injection in Detecting or Excluding Dopaminergic Deficits in Subjects with 1 or More Signs of a Parkinsonian Syndrome [Total award: $58,375]


Publications:

Selected Peer-Reviewed Journals

Khosla J, Edelman MJ, Kennedy N, Reich SG. West Nile virus presenting as opsoclonus-myoclonus cerebellar ataxia. Neurology 2005;64:1095.

Nichols WC, Pankratz N, Hernandez D, Paisan-Ruiz, C, Jain S, Halter CA, Michaels VE, Reed T, Rudolph A, Shults CW, Singleton A, Forout T, Parkinson Study Group-PROGENI Investigators (S. Reich). Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease. Lancet 2005;365:410-412.

Crone NE, Jinnah HA, Reich SG. Wilson disease presenting with an unusual cough. Movement Disorders 2005;20:891-893.

Reich SG, Grill SE. Gustatory sweating: Frey’s syndrome. Neurology 2005;65:E24.

Gilman S, May SJ, Shults CW, Tanner CM, Kukull W, Lee VM, Masliah E, Low P, Sandroni P, Trojanowski JQ, Ozelius L, Foroud T; and The North American Multiple System Atrophy Study Group (S. Reich) .The North American multiple system atrophy study group. J Neural Transm 2005;112:1687-1694

Reich SG. Invited commentary:  New and reliable MRI diagnosis for progressive supranuclear palsy. Nature Clinical Practice Neurology 2006;2:12-13.

Blindauer K, Shoulson I, Oakes D, Kieburtz K, Schwid S, Fahn S, Stern M, Goetz C, Nutt J, Goren S, Sayag N, Scolnik M, Levy R, Eyal E, Salzman P, Pagano M; Parkinson Study Group (Reich SG). A randomized controlled trial of etilevodopa in patients with Parkinson disease who have motor fluctuations. Archives of Neurology 2006;63:210-216

Schneider SA, Edwards MJ, Grill SE, Goldstein S, Kanchana S, Quinn NP, Bhatia KP, Hallett M, Reich SG. Adult-onset primary lower limb dystonia. Movement Disorders 2006;2:767-771.

Shulman LM, Stevenson R, Anderson KE, Vaughan CG, Gruber-Baldini A, Reich SG, Weiner WJ. Subjective report vs. objective measurement of activities of daily living in Parkinson’s disease. Movement Disorders 2006;21:794-799.

Jinnah HA, Visser JE, Harris JC, Verdu A, Larovere L, Cebbalos-Picot, Neychev V, Torres R, Dulac O, Desguerre I, Schretlen DJ, Robey KL, Barabas G, Bloen BR, Nyhan W, de Kremer R, Eddey GE, Puig J, Reich SG. Delienation of the motor disorder of Lesch-Nyhan disease. Brain 2006;129:1201-1217.
 
Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ. Practice parameter: diagnosis and prognosis of new onset Parkinson disease. Neurology 2006;66:968-975.

Suchowersky O, Gronseth G,  Perlmutter J, Reich S, Zesiewicz T, Weiner WJ. Practice parameter: neuroprotective strategies and alternative therapies for Parkinson disease. Neurology 2006;66:976-982.

Haines S, Chen H, Anderson KE, Fishman PS, Shulman LM, Weiner WJ, Reich SG. When do patients with Parkinson disease disclose their diagnosis? Neurology 2006;67:488-90.

Reich SG. Bell palsy: which side? (Teaching NeuroImage). Neurology 2007;682:E1.

Mutations in LRRK2 other than G2019S are rare in a North American-based sample of familial Parkinson disease. Pankratz N, Pauciulo MW, Elsaesser VE, Marek DK, Halter CA, Rudolph A, Shults CW, Foroud T, Nichols WC and the Parkinson Study Group-PROGENI Investigators (S. Reich). Movement Disorders 2006;21: 2257-2260.

Mutations in DJ-1 are rare in familial Parkinson disease. Pankratz N, Pauciulo MW, Elsaesser VE, Marek DK, Halter CA, Wojcieszek J, Rudolph A, Shults CW, Foroud T, Nichols WC and the Parkinson Study Group-PROGENI Investigators (S. Reich). Neuroscience Letters 2006;408:209-213.

R1514Q substitution in LRRK2 is not a pathogenic Parkinson disease mutation. Nichols WC, Marek DK, Pauciulo MW, Pankratz N, Halter C, Rudolph A, Shults C, Wojcieszek J, Foroud T and the Parkinson Study Group-PROGENI investigators (S. Reich). Movement Disorders 2007;22:254-257.

Ozelius Laurie J., Foroud T, May S, Senthil G, Sandroni P, Low PA, Reich SG, Colcher A, Stern MB, Ondo WG, Jankovic J, Huang N, Tanner CM, Novak P, Gilman S, Marshall FJ, Wooten GF, Chelimsky TC, Shults CW, and the North American Multiple System Atrophy Study Group. The G2019S mutation in LRRK2 is not associated with multiple system atrophy. Movement Disorders (in press).

Boatman DF, Miglioretti DL, Eberwein C. Alidoost M. Reich SG. How accurate are bedside hearing tests? Neurology 2007;68:1311-1314.

Reich SG. It is III alone, or III and IV? (Teaching NeuroImage). Neurology 2007;68:E34. 

Anderson KE, Gruber-Baldine AL, Vaughn CG, Reich SG, Fishman PF, Weiner WJ. The impact of psychogenic movement disorders on psychiatric co-morbidity, disability, and quality of life compared to Parkinson’s disease. Movement Disorders (in press).

Solomon D, Ramat S, Tomsak RL, Reich SG, Shin R, Zee DS, Leigh RJ. Saccadic Palsy Following Cardiac Surgery: Characteristics and Pathogenesis. Annals of Neurology (in press).

May S, Gilman S, Sowell BB,Thomas RG, Stern MB, Colsher A, Tanner CM, Huang N, Novak P, Reich SG, Jankovic J, Ondo WG, Low PA, Sandroni P, Lipp A, Marshall FJ, Wooten F, Shults CW, and the North American Multiple System Atrophy Study Group. Potential Outcome Measures and Trial Design Issues for Multiple System Atrophy. Movement Disorders (in press).


Book Chapters

Reich SG, DeLong MR. Parkinson's Disease.  In Johnson RT (ed).  Current Therapy in Neurologic Disease.  Philadelphia:BC Decker, 1990, 247-252.  (Reprinted in:  Kassirer JP (ed), Current Therapy in Internal Medicine (3rd Ed).  Philadelphia:  BC Decker, 1991, 1673-1677).

Alexander GE, Reich SG, DeLong MR.  Torticollis. In Johnson RT (ed).  Current Therapy in Neurologic Disease.  Philadelphia:BC Decker, 1990, 275-278.

Reich SG, DeLong MR. Parkinson's Disease.  In Johnson RT (ed).  Current Therapy in Neurologic Disease.  Philadelphia:BC Decker, 1990, 247-252.  (Reprinted in:  Kassirer JP (ed), Current Therapy in Internal Medicine (3rd Ed).  Philadelphia:  BC Decker, 1991, 1673-1677).

Alexander GE, Reich SG, DeLong MR.  Torticollis. In Johnson RT (ed).  Current Therapy in Neurologic Disease.  Philadelphia:BC Decker, 1990, 275-278.

Reich SG, DeLong MR.  Common Disorders of Movement: Tremor and Parkinson's Disease. In Barker LR, Burton JR, Zieve PD (eds).  Principles of Ambulatory Medicine (Third ed).  Baltimore: Williams and Wilkens, 1991, 1133-1143.

Reich SG.  Progressive Supranuclear Palsy.  In Johnson RT, Griffin J (eds).  Current Therapy in Neurology.St. Louis, BC Decker, 1993, 250-253.

Reich SG. Common disorders of movement: Tremor and Parkinson's disease.  In Barker LR, Burton JR, Zieve PD (eds). Principles of Ambulatory Medicine (Fourth ed.). Baltimore:Williams and Wilkens, 1995, 1217-1229.

Reich SG. Movement Disorders. In Stobo JD, Hellmann DB, Ladenson PW, Petty BG, Traill TA (eds). The Principles and Practice of Medicine. Stamford:Appleton and Lange 1996, 852-856.

Reich SG. Dystonia. In Johnson RT, Griffin JW (eds). Current Therapy of Neurologic Disease (Fifth edition). Philadelphia: Mosby 1996, 286-290. 

Zirh TA, Reich SG, Perry V, Lenz FA.  Thalamic single neuron activity in patients with dystonia.  In Fahn S, Marsden CD, DeLong M. Advances in Neurology, Dystonia 3 Philadelphia: Lippincott-Raven, 1998, 27-32.

Reich SG.  Common disorders of movement: tremor and Parkinson's disease: In Barker LR, Burton JR, Zieve PD (eds). Principles of Ambulatory Medicine (Fifth Edition).  Baltimore: Williams & Wilkins 1274-1285, 1998. 

Reich SG.  Approach to the patient with a gait disorder. In Humes HD, et al.  Kelley's Textbook of Internal Medicine (4th edition).  Philadelphia: Lippincott Williams & Wilkens  2881-2884, 2000.

Reich SG.  Approach to the patient with abnormal movements and tremors.  In Humes HD, et al.  Kelley's Textbook of Internal Medicine (4th edition).  Philadelphia: Lippincott Williams & Wilkens, 2884-2888, 2000.

Reich SG.  Parkinson's Disease and related disorders.   In Humes HD, et al.  Kelley's Textbook of Internal Medicine (4th edition).  Philadelphia: Lippincott Williams & Wilkens 2915-2918, 2000.

Reich SG. Tremor. In: Slavney PR, Hurko O (eds). Common Neurologic and Psychiatric Disorders Seen and Treated by Primary Care Physicians. Baltimore: Johns Hopkins University Press 214-230, 2001.   

Reich SG, Flint PW, Purcell L,.  Dyphagia and Dysarthria.  In Johnson RT, Griffin J, McArthur JC: Current Therapy in Neurolgic Disease. St Louis: Mosby 322-324, 2002. 

Reich SG, Jinnah H.  Restless Legs Syndrome.  In  Katirji B, Kaminski HJ, Preston DC, Ruff RL, Shapiro BE: Neuromuscular Disorders in Clinical Practice. Boston: Butterworth-Henemann 1334-1341, 2002. 

Reich SG. Parkinson’s Disease. In Albrecht G, Bichenbach J, Mitchell D, Snyder S, Schailak W. The Encyclopedia of Disability. Sage Press (in press).