Bookmark and Share

Mohammad M. Sajadi

Mohammad M. Sajadi M.D.

Academic Title: Associate Professor
Primary Appointment: Medicine
Additional Title(s): Assistant Professor, Division of Clinical Care and Reserach, Institute of Human Virology
Location: Institute of Human Virology N548
Phone: 410-706-1779
Fax: 410-706-1992
Lab: 410-706-4652

Personal History:

Dr. Mohammad Sajadi oversees the NVS cohort, HIV-1 infected patients who control viral replication in the absence of HIV therapy. I have been studying the NVS and other HIV patients with low viral loads as a model to study HIV humoral immunity. I work closely with the Division of Basic Science and Vaccine Research, and oversee a project to directly sequence antibody from patient plasma, as well as studying the common characteristics of antibodies that mediate the neutralization response in HIV infection.


  1. Guan Y, Pazgier M, Sajadi MM, Kamin-Lewis R, Al-Darmarki S, Flinko R, Lovo E, Wu X, Robinson JE, Seaman MS, Fouts TR, Gallo RC, DeVico AL, Lewis GK. Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):E69-78. PMCID: PMC3538257
  2. Sajadi MM, Pulijala R, Redfield RR, Talwani R. Chronic immune activation and decreased CD4 counts associated with Hepatitis C Infection in HIV-1 Natural Viral Suppressors. AIDS. 2012 Sep 24;26(15):1879-84. PMCID: PMC3772623
  3. Sajadi MM, Lewis GK, Seaman MS, Guan Y, Redfield RR, DeVico AL. Signature biochemical properties of broadly cross-reactive HIV-1 neutralizing antibodies in human plasma. J Virol. 2012 May;86(9):5014-25. PMCID: PMC3347347
  4. Sajadi MM, Guan Y, Devico AL, Seaman MS, Hossain M, Lewis GK, Redfield RR. Correlation between circulating HIV-1 RNA and broad HIV-1 neutralizing antibody activity. J Acquir Immune Defic Syndr. 2011 Jan 28. PMCID: PMC3110998
  5. Sajadi MM, Shakeri N, Talwani R, Redfield, RR. Hepatitis C infection in HIV-1 Natural Viral Suppressors. AIDS. 2010 Jul 17;24(11):1689-95. PMCID: PMC2894991
  6. Y Guan, MM Sajadi, R Kamin-Lewis, T Fouts, A Dimitrov, Z Zhang, R Redfield, AL DeVico, R Gallo, GK Lewis. Humoral Immunity against Conserved Epitopes of the HIV-1 Envelope Protein Archived in Memory B cells in Natural Viral Suppressors: Discordance with Plasma Antibodies. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3952-7. PMID: 19225108
  7. MM Sajadi, NT Constantine, DL Mann, M Charurat, E Dadzan, P Kadlecik, RR Redfield. Epidemiologic Characteristics and Natural History of HIV-1 Natural Viral Suppressors. J Acquir Immune Defic Syndr. 2009 Apr 1;50(4):403-8.
  8. DJ Riedel, MM Sajadi, CL Armstrong, JS Cummings, C Cairo, RR Redfield, CD Pauza. Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cells. AIDS. 2009 Jul 15. PMID: 19609200
  9. A Yadav, P Fitzgerald, MM Sajadi, B Gilliam, MK Lafferty, R Redfield, W Reid. Increased expression of Suppressor of Cytokine Signaling-1 (SOCS-1): A mechanism for dysregulated T helper-1 responses in HIV-1 Disease. Virology. 2009 Mar 1;385(1):126-33. Epub 2009 Jan 9.PMID: 19135225
  10. MM Sajadi, A Heredia, N Le, N Constantine, R Redfield. HIV-1 Natural Viral Suppressors: Control of Viral Replication in the Absence of Therapy. AIDS. 2007 Feb 19;21(4):517-9.