SOM Faculty Profile : Hongbin Fang

Hongbin Fang

Hongbin Fang Ph.D.

Academic Title: Assistant Professor

Primary Appointment: Epidemiology and Preventive Medicine

Secondary Appointments: School of Pharmacy

hfang@som.umaryland.edu

Location: MSTF, 261

Phone: (410) 706-4103

Phone: (410) 706-8505

Fax: (410) 706-8548

Personal History

Hongbin Fang is a UMGCC faculty biostatistician and an assistant professor of Epidemiology and Preventive Medicine. After he received his Ph.D. in statistics from Hong Kong Baptist University in 1998, Dr. Fang worked on statistical methods on survival models as related to AIDS research at University of Missouri as a postdoctoral fellow and then joined the Department of Biostatistics at St. Jude Children's Research Hospital in 2000 as a postdoctoral research associate. He joined UMGCC in 2002 and has collaborated with investigators in several research programs at the cancer center. He is a member of the center's Experimental Therapy section.

Research Interests

Experimental design and statistical analysis for drug development, statistical methods for radiation biology and oncology, interval censored survival and multivariate survival analysis models.

Publications

Fang, H.B., Ross, D.D., Sausville, E. and Tan, M. (2008), Experimental design and interaction analysis of combination studies of drugs with log-linear dose responses. Statistics in Medicine, in press.

Tan, M., Tian, G.L., Fang, H.B. and Ng, K.W. (2007), A fast EM algorithm for quadratic optimization subject to convex constraints. Statistica Sinica, 17(3), 945-964.

Fan T, Li R, Todd NW, Qiu Q, Fang HB, Wang H, Shen J, Zhao RY, Caraway NP, Katz RL, Stass SA and Jiang F. (2007). Up-regulation of 14-3-3(zeta) in lung cancer and its implication as prognostic and therapeutic target, Cancer Research, 67(16), 7901-7906.

Fang, H.B., Tian, G.L., Xiong, X. and Tan, M. (2006), A Restricted Multivariate Random-Effects Model with Applications to Assessing Radiation Therapy for Brain Tumors. Statistics in Medicine 25, 1948-1959.

Rapoport AP, Stadtamauer EA, Aqui N, Badros A, Cotte J, Chrisley L, Veloso E, Zheng Z, Westphal S, Mair R, Chi N, Ratterree B, Pochran MF, Natt S, Hinkle J, Sickles C, Sohal A, Ruehle K, Lynch C, Zhang L, Porter DL, Luger S, Guo C, Fang HB, Blackwelder W, Hankey K, Mann D, Edelman R, Frasch C, Levine B, Cross A, and June CH. (2005). Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer, Nature Medicine, 11(11), 1230-1237.

Fang, H.B, Li, G. and Sun, J. (2005), Maximum likelihood estimation in a semiparametric logistic/proportional-hazards mixture model. Scandinavian Journal of Statistics, 32, 59-75.

Tan, M., Fang, H.B., Tian, G.L. and Houghton, P.J. (2005), Repeated-measures models with constrained parameters for incomplete data in tumor xenograft experiments. Statistics in Medicine 24, 109-119.

Fang, H.B., Tian, G.L. and Tan, M. (2004). Hierarchical models for tumor xenograft experiments in drug development. Journal of Biopharmaceutical Statistics 14, 931-945.

Tan, M., Fang, H.B., Tian, G.L. and Houghton, P.J. (2003), Experimental design and sample size determination for drug combination studies based on uniform measures. Statistics in Medicine 22, 2091-2100.

Sun, J. and Fang, H.B. (2003), A nonparametric test for panel count data, Biometrika 90, 199-208.

Fang, H.B., Sun, J. and Lee, M.L.T. (2002), Nonparametric survival comparisons for interval-censored continuous data, Statistica Sinica 12, 1073-1083.

Tan, M., Fang, H.B., Tian, G.L. and Houghton, P.J. (2002), Small-sample inference for incomplete longitudinal data with truncation and censoring in tumor xenograft models, Biometrics 58, 612-620.

Fang, H.B., Fang, K.T., and Kotz, S. (2002), The meta-elliptical distributions with given marginals, Journal of Multivariate Analysis 82, 1-16.

Faculty members: Click here to update your contact information and create a profile.