Research InterestsDr. Blumenthal is an Assistant Professor and recent recipient of a Veterans Administration Advanced Research Career Development Award. His research is designed to determine the effects of aging and obesity on cytokine production by adipose tissue and their relationship to systemic levels and constituents of the metabolic syndrome, as well as examine the effect(s) of weight loss and aerobic exercise training in an older subset of subjects. As a clinically trained geriatrician, his research goals are to translate his mechanistic investigations into clinically relevant interventions that can reduce cardiovascular disease and diabetes risk in older individuals. As an investigator in the Baltimore VA Geriatric Research, Education and Clinical Center (GRECC), he is developing techniques to measure macrophages in adipose tissue to examine mechanisms regulating cytokine production in adipose tissue biopsies; race and gender differences in metabolic risk factors; and the interactions of gene variants, aging and environment in the regulation of lipid and glucose metabolism in obese older adults.
In addition to his research, Dr. Blumenthal is active in the clinical and educational missions of the Division and the GRECC. He led the
Lyndon Joseph, Jacob Blumenthal, Leslie Katzel, and Andrew Goldberg . Exercise Training and Cardiovascular Health with Aging. Clinical Geriatrics 2005; 13(4): 40-6 .
Walston J, Andersen RE, Seibert M, Hilfiker H, Beamer B, Blumenthal J, Poehlman ET. Arg64 beta(3)-Adrenoceptor Variant and the Components of Energy Expenditure. Obesity Research 2003; 11(4): 509-11.
Blumenthal JB, R Andersen, B Mitchell, M Seibert, H Yang, H Herzog, B Beamer,