Personal History1980-1984: Boston University School of Medicine
1984-1987: University of Chicago Hospitals and Clinics; Medicine 1987-1990: Residency, University of Chicago Hospitals and Clinics;
1990-1991: Nephrology Fellowship, Children's Memorial Hospital, Northwestern Univ; Pediatric Nephrology
Research InterestsDr. Mendley's research interests include the impact of chronic kidney disease on growth and neurocognitive development in children, and she plays an integral role in the NIH-sponsored Chronic Kidney Disease in Childhood multi-center study investigating this area. She has investigated optimal methods for measuring delivery of dialysis to children of all ages and sizes and how to insure adequacy of dialysis in children. Further, she studies anti-hypertensive therapy for children with high blood pressure and obstacles to adherence in this unique patient population.
Clinical SpecialityDr. Mendley directs the Division of Pediatric Nephrology, supervising consultative nephrology, kidney transplantation, inpatient acute dialysis and outpatient peritoneal dialysis and hemodialysis.
Mendley, S.R., N.L. Majkowski and P.K. Higgins. Estimation of urea and creatinine clearances in peritoneal dialysis. ASAIO J. 38:M373-M376, 1992.
Mendley, S.R., J.G. Umans and N.L. Majkowski. Measurement of peritoneal dialysis delivery in children. Pediatric Nephrolology 7:284-289, 1993.
Mendley, S.R., A.K. Poznanski, B.H. Spargo, and C.B. Langman. Hereditary sclerosing glomerulopathy in the conorenal syndrome. American Journal of Kidney Disease 25:792-797, 1995.
Mendley, S.R. and N.L. Majkowski. Peritoneal equilibration test results are different in infants, children, and adults. Journal of the American Society of Nephrology 6:1309-1312, 1995.
Majkowski, N.L. and S.R. Mendley. Simultaneous removal and replacement of infected peritoneal dialysis catheters. American Journal of Kidney Disease 29:706-711, 1997.
Mendley, S.R. and F. Zelko. Improvement in specific aspects of neurocognitive performance in children after renal transplantation. Kidney International 56:318-323, 1999.
Mendley, S.R. and N.L. Majkowski. Urea and nitrogen excretion in pediatric peritoneal dialysis patients. Kidney International 58:2564-2570, 2000
Salimi, B., E. Alonso, R. Cohn, S. Mendley, B.Z. Katz. Comparison of immortalization assay and polymerase chain reaction detection of Epstein-Barr virus in pediatric transplant recipients and control samples. Pediatric Pathology and Molecular Medicine, 21:433-443, 2002.
Drachenberg, C.B., J.C. Papdimitriou, H.H. Hirsch, R Wali, C. Crowder, J. Noguiera, C.B. Cangro, S. Mendley, A. Mian, E. Ramos. Histological patterns of polyomavirus nephropathy: Correlation with graft outcome and viral load. American Journal of Transplantation, 4:2082-92 2004.
Drachenberg, C.B., J.C. Papadimitriou, R. Wali, J. Nogueira, S. Mendley, H.H. Hirsch, C.B. Cangro, D.K. Klassen, M.R. Weir, S.T. Bartlett, E.Ramos. Improved outcome of polyoma virus allograft nephropathy with early biopsy. Transplantation Proceedings, 36:758-9, 2004.
Drachenberg C, Hirsch HH, Papdimitriou JC, Mozafari P, Wali R, McKinney JD, Nogueira J, Cangro CB, Mendley S, Klassen DK, Ramos E. Cost efficiency in the prospective diagnosis and follow-up of polyomavirus allograft nephropathy. Transplantation Proceedings, 36:3028-31, 2004.
Mian, A.N., A.C. Farney, S.R. Mendley. Mycoplasma hominis septic arthritis in a pediatric renal transplant recipient. American Journal of Transplantation, 5:183-8, 2005.
Mendley, S.R., N.L. Majkowski, D.A. Schoeller. Validation of estimates of total body water in pediatric dialysis patients by deuterium dilution. Kidney International, 67:2056-2062, 2005.
Drachenberg CB, Hirsch HH, Papdimitriou JC, Gosert R, Wali RK, Munivenkatappa R, Nogueira J, Cangro CB, Haririan A, Mendley S, Ramos E. Polyomavirus BK versus JC replication and nephropathy in renal transplant recipients: a prospective evaluation. Transplantation, 84(3):323-30, 2007.
Gerson, AC, Wentz, A, Abraham, AG, Mendley, SR, Hooper, SR, Butler, RW, Gipson, DW, Lande, MB, Shinnar, S, Moxey-Mims, MM, Warady, BA, Furth, SL. Health-Related Quality of Life of Children With Mild to Moderate Chronic Kidney Disease. Pediatrics Feb 125(2):e349â?"357, 2010.
Hooper, S, Gerson, A, Butler, R, Gipson, D, Mendley, S, Lande, M, Shinnar, S, Wentz, A, Cox, C, Furth, S, Warady, B. Neurocognitive Functioning of Children and Adolescents with Mild to Moderate CKD. Clin J Am Soc Nephrol, 6 (8):1824-30, 2011.
Lande, M, Gerson, A, Hooper, S, Cox, C, Matheson, M, Mendley, S, Gipson, D, Wong, C, Warady, B, Furth, S, Flynn, J. Casual Blood Pressure and Neurocognitive Function in Children with Chronic Kidney Disease: A Report of the Children with Chronic Kidney Disease Cohort Study. Clin J Am Soc Nephrol, 6 (8):1831-37, 2011
INVITED CHAPTERS, PAPERS, and REVIEWS
Mendley, S.R., and F.G. Toback. Autocrine and paracrine regulation of renal epithelial cell growth. Annual Review of Physiology 51:33-50, 1989.
Mendley, S.R. and F.G. Toback. Cell proliferation in the end-stage kidney. American Journal of Kidney Disease 16:80-84, 1990.
Toback, F.G., M.M. Walsh-Reitz, S.R. Mendley, S. Kartha. Kidney epithelial cells release growth factors in response to extracellular signals. Pediatric Nephrology 4:363-371, 1990.
Mendley, S.R. and C.B. Langman. Acute renal failure in the pediatric patient. Adv Renal Repl Ther 4 (Suppl.1):93-101, 1997.
Mendley, S.R., R.N. Fine, A. Tejani. Dialysis in Infants and Children. Handbook of Dialysis, third edition. J.T. Daugirdas and T.S. Ing, eds., Little Brown, 2000.
Mendley, S.R. Pediatric Hypertension. The Kidney and Hypertension. G. Bakris ed. London, Martin Dunitz 2004.
Mian, A.N. and S.R Mendley. Acute Renal Replacement Therapy for the Pediatric Patient. Principles and Practice of Dialysis. W. Heinrich, ed. Philadelphia, Lippincott Williams & Wilkins 2004.
Mian, A.N. and S.R Mendley Pediatric ICU Nephrology. Intensive Care in Nephrology. P. Murray, H.R. Brady, J.B.Hall ed. Martin Dunitz, 2006.
Mendley, S.R. Dialysis in Infants and Children. Handbook of Dialysis, fourth edition. J.T. Daugirdas, P.G. Blake and T.S. Ing, eds., Little Brown, 2006.
Gerson A.C., R. Butler, M. Moxey-Mims, A. Wentz, S. Shinnar, M.B. Lande, S.R. Mendley, B.A. Warady, S.L. Furth, S.R. Hooper. Neurocognitive outcomes in children with chronic kidney disease: current findings and contemporary endeavors. Mental Retardation and Developmental Disabilities Research Reviews 12(3):208-215, 2006.
S.R Mendley. Acute Dialysis in Children. Principles and Practice of Dialysis, fourth edition. W. Heinrich, ed. Philadelphia, Lippincott Williams & Wilkins 2008.
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