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Olga B. Ioffe M.D.

Academic Title: Professor
Primary Appointment: Pathology
Administrative Title: Associate Chair For Education, Division Head, Anatomic Pathology
Location: UMMC, NBW56
Phone: (410) 328-1345
Phone: (410) 328-5525
Fax: (410) 328-5508

Personal History:

M.D.,Moscow State Medical Institute, 1978-1984, Moscow, Russia
Postgraduate Education
Resident in Internal Medicine, 1992-1993, Department of Internal Medicine, Greater Baltimore Medical Center, Baltimore, MD                                                                                                  
Resident in Pathology (AP/CP), 1993-1997, Department of Pathology, University of Maryland School of Medicine,  Baltimore, MD
Chief Resident, Pathology Residency Training Program, 1996-1997, Department of Pathology, University of Maryland School of Medicine, Baltimore, MD
Fellow, Surgical Pathology, 1997-1998, Department of Pathology, University of Maryland School of Medicine, Baltimore, MD,  Director: Steven G. Silverberg, M.D.

Research Interests:

Breast and Gynecologic pathology

Clinical Speciality:

Surgical Pathology


Selected Publications:

Ioffe, O.B., Berg, W.A., Silverberg, S.G., and Kumar, D.: Mammographic-histopathologic correlation of large core needle breast biopsies. Modern Pathology, 11:721-727, 1998

Ioffe, O.B., Papadimitriou, J.C., Simmons, J., and Drachenberg, C.B.: Correlation of proliferation indices, apoptosis and related oncogene expression (bcl-2, p53 and c-erbB-2) in benign, hyperplastic and malignant endometrium. Human Pathology, 29:1150-1159, 1998

Ioffe, O.B., Rezende, R.B., Brooks, S.E., and Silverberg, S.G.: Thermal artifact in cervical LEEP specimens: Correlation with follow-up. International Journal of Gynecological Pathology, 18: 115-121, 1999

Berg W.A., Mrose H.E., Ioffe O.B.: Atypical lobular hyperplasia or lobular carcinoma in situ at core-needle breast biopsy. Radiology, 218:503-9, 2001.

Simsir, A., Brooks, S.E., Cochran, L., Bourquin, P., Ioffe, O.B.,: Cervicovaginal smear abnormalities in sexually active adolescents. Implications for management. Acta Cytologica, 46:271-6, 2002.

Ioffe, O.B., Sagae S., Moritani S., Dahmoush L., Chen T., and Silverberg, S.G.: Should pathologists diagnose endocervical preneoplastic lesions â?oless thanâ? adenocarcinoma in situ? Int J Gynecol Pathol, 22:18-21,2003.

Ioffe, O.B., Sagae S., Moritani S., Dahmoush L., Chen T., and Silverberg, S.G.: Proposal of a new scoring scheme for the diagnosis of non-invasive endocervical glandular lesions. Am J surg Pathol, 27:452-60,2003.

Gill H.K., Ioffe, O.B., Berg, W.A.: When is a diagnosis of sclerosing adenosis acceptable on core biopsy? Radiology, 228:50-57,2003.

Berg, W.A., Campassi, C.I., Ioffe, O.B.: Cysts, complicated cysts and complex cystic masses of the breast: sonographic-histopathologic correlation. Radiology, 227:183-91,2003

Serrero G., Ioffe, O.B.: Expression of PC-cell derived growth factor (PCDGF) in benign and malignant human breast tissue. Human Pathology, 34:1148-54, 2003

Jiao, X., Eslami, A., Ioffe, O.B., Kwong, K.F., Henry, M., Zeng, Q., Refaely, Y., Burrows, W., Gamliel, Z., Krasna, M.J.: Immunohistochemistry analysis of micrometastasis in pretreatment lymph nodes from patients with esophageal cancer. Ann Thorac Sur,.76:996-9, 2003

Nikitakis, N.G., Tosios K.I., Papanikolaou, V.S., Rivera, R., Papanicolaou, S.I., Ioffe, O.B. : Immunohistochemical expression of cytokeratins 7 and 20 in malignant salivary gland tumors. Mod Pathology, 17:407-15, 2004

Gallicchio, L., Flaws, J.A., Sexton, M., Ioffe, O.B. : Cigarette smoking and Methallothionein expression in invasive breast carcinomas. Toxicol Letters, 152:245; 2004

Berg, W.A., Gutierrez, L., NessAiver, M.S., Carter, W.B., Bhargavan, M., Lewis, R.S., Ioffe, O.B. : Diagnostic Accuracy of Mammography, Ultrasound, and Magnetic Resonance Imaging in Preoperative Assessment of the Local Extent of Breast Cancer. Radiology, 233:830, 2004

Gallicchio, L., Flaws, J.A., Fowler, B.A., Ioffe, O.B. : Metallothionein expression in invasive and in situ breast carcinomas. Cancer Detection and Prevention, 29:332, 2005.

Wolfson, A.H., Brady, M.F., Rocereto, T.F., Mannel, R.S., Lee, Y.-C., Futoran, R., Cohn, D., Ioffe, O.B. : A Gynecologic Oncology Group randomized phase III trial of whole abdominal irradiation vs Cisplatin-Ifosfamide and Mesna as post-surgical therapy in stage I-IV carcinosarcoma of the Uterus. Gynecol Oncol ,107:177-85, 2007

Lacey, J.L., Ioffe, O.B., Ronnett B.M., Rush, B.B., Richesson, D.A., Chatterjee, N., Langholz, B., Glass, A.G., Sherman, M.E.: Progression risk for endometrial hyperplasia: the 34-year experience in a large health plan. Br J Cancer. In Press