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Kristi D. Silver

Kristi D. Silver M.D.

Academic Title: Associate Professor
Primary Appointment: Medicine
Additional Title(s): Acting Director, University of Maryland Center for Diabetes and Endocrinology; Director, Endocrinology, Diabetes and Metabolism Fellowship Program
Location: Howard Hall, Room 494
Phone: (410) 706-1628
Fax: (410) 706-1622

Personal History:

Dr. Silver received her MD degree from the University of Maryland School of Medicine. She completed her residency in internal medicine at the University of Massachusetts Medical Center and her fellowship in Endocrinology, Diabetes and Metabolism at the Johns Hopkins University School of Medicine. Dr. Silver is board certified in both Internal Medicine and Endocrinology and Metabolism. Dr. Silver joined the faculty at the University of Maryland School of Medicine in 1997.

Research Interests:

Dr. Silver's research interests include the genetics of insulin secretion, pharmacogenetics/pharmacogenomics of diabetes medications and inpatient and outpatient diabetes management.

Clinical Speciality:

Dr. Silver sees patients with diabetes and other endocrine disorders.


Search My Publications in Pub Med

Highlighted Publications

Walston J, Silver K, Bogardus C, Knowler WC, Celi FS, Austin S, et al. Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene. N Engl J Med. 1995;333(6):343-7.

Walston J, Silver K, Hilfiker H, Andersen RE, Seibert M, Beamer B, et al. Insulin response to glucose is lower in individuals homozygous for the Arg 64 variant of the beta-3-adrenergic receptor. J Clin Endocrinol Metab. 2000;85(11):4019-22.

Silver K, Yao F. ARIP cells as a model for pancreatic beta cell growth and development. Pancreas. 2001;22(2):141-7.

Silver K, Shetty A. IPF-1 gene variation and the development of type 2 diabetes. Mol Genet Metab. 2002;75(3):287-9.

Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, et al. Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance. Diabetes. 2006;55(9):2654-9.

Silver KD, Magnuson VL, Tolea M, Wang J, Hagopian WA, Mitchell BD. Association of a polymorphism in the betacellulin gene with type 1 diabetes mellitus in two populations. J Mol Med (Berl). 2006;84(7):616-23.

Silver KD, Shi X, Mitchell BD. Betacellulin variants and type 2 diabetes in the Old Order Amish. Exp Clin Endocrinol Diabetes. 2007;115(4):229-31.

Naj AC, Kao WH, O'Connell JR, Mitchell BD, Silver KD. Sequence variation in IGF1R is associated with differences in insulin levels in nondiabetic Old Order Amish. Diabetes Metab Res Rev. 2009;25(8):773-9.

Wang X, Yang R, Jadhao SB, Yu D, Hu H, Glynn-Cunningham N, et al. Transmembrane emp24 protein transport domain 6 is selectively expressed in pancreatic islets and implicated in insulin secretion and diabetes. Pancreas. 2012;41(1):10-4.