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Eric D Strauch
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Eric D Strauch M.D.

Academic Title: Associate Professor
Primary Appointment: Surgery
estrauch@smail.umaryland.edu
Location: UMMC, N4E37
Phone: (410) 328-5730
Fax: (410) 328-0652

Personal History:

EDUCATION

1980-83: BA, Biology, The Johns Hopkins University, Baltimore, MD
1983-84: MS, Physiology, Georgetown University, Washington, DC
1984-88: MD, University of Maryland School of Medicine, Baltimore, MD
1988-94: Surgery Resident, University of Maryland Medical Center
1994-96: Pediatric Surgery Fellow, The Johns Hopkins University School of Medicine and University of Maryland School of Medicine, Baltimore, MD

Employment

1996-2005: Assistant Professor of Surgery, The University of Maryland School of Medicine, Baltimore, MD
2005-present: Associate Professor of Surgery, The University of Maryland School of Medicine, Baltimore, MD


Current Research Support:

Principal Investigator (4/1/08-3/31/10)
The Critical Role of Bile Salts: Gut Protection in Critical Illness
R21 RDK075409A
NIH/NIDDK
Total Direct Costs Awarded ($275,000)

Co-Principal Investigator (7/1/07-6/30/12)
Mucosal Repair in Gut Surgical Disorders
R01 DK 061972
NIH/NIDDK
Total Direct Costs Awarded ($928,750)

Publications:

Strauch ED, Fabian DF, Turner J, Lefor AT. The combined effect of adoptive immunotherapy and hyperthermia in the treatment of multiple pulmonary metastases in mice.  Surg. Onc. 3(1): 45-52, 1994

Nelms C, Alvarez C, Strauch E, Lally K, Bass B. Glycocholic and taurocholic acids stimulate esophageal mucosal repair. Surg Forum 48:156-158, 1997.

Benson JE, Strauch ED. Retropsoas hernia as a cause of chronic abdominal pain: CT diagnosis. Pediatr Radiol 28:312-314, 1998.

Toretsky JA, Zitomersky N, Eskenazi AE, Voigt RW, Strauch ED et al. Glypican-3 Expression in Wilms Tumor and Hepatoblastoma. J.Pediatr. Hem/Onc., Nov; 23(8): 496-499, 2001

Rao JN, Li Li, Golovina VA, Platoshyn O, Strauch ED et al. K+ Channels Regulate Polymaine-Dependent Intestinal Epithelial Cell Migration Through CA2+RHOA Signaling Pathway. Am. J. Physiol. Cell Physiol., 280: C993-C1007, 2001

Strauch ED, Wang JY, Bass BL. Bile Salt Stimulates Intestinal Epithelial Cell Migration through TGFB after wounding. J. Surg, Research, 97(1): 49-53, 2001

Strauch ED, Voigt RW, Hill JL. Gangrenous Intestine in a Hernia Can Be Reduced. J. Pediatr. Surg, 37(6) 919-920, 2001

Li Li, Liu L, Rao JN, Esmaili A, Strauch ED et al.  JunD Stabilization Results in Inhibition of Normal Intestinal Epithelial Cell Growth Through P21 After Polyamine Depletion. Gastroenterology, 123: 764-779, 2002

Strauch ED, Bass BL,Rao JN, Vann JA, Wang, JY. NF-κB Regulates Intestinal Epithelial Cell and Bile Salt Induced Migration after Injury. Ann Surg, 237: 494-501, 2003.

Xie XY, Strauch ED, Sun CCJ. Choledochal Cyst and Multilocular Cyst of Pancreas. J. Human Path., 34 (1) 99-101, Jan  2003

Yamaguchi J, Toledo A, Bass GL, Celeste FA, Rao JN, Wang J-Y, Strauch ED. Taurodeoxycholate Increase Intestinal Epithelial Cell Proliferation through C-myc Expression. Surgery  135 (2): 215-21, Feb 2004.

Strauch ED, Yamaguchi J, Bass BL, Wang J-Y. Bile Salts Regulate Intestinal Epithelial Cell Migration by NF-kappa Beta-Induced Expression of TGF-β.  J Am Coll Surg. 197 (6): 974-84, Dec 2003.

Zou T, Rao JN, Guo X, Liu L, Zhang HM, Strauch ED, Bass BL, Wang JY:  NF-κB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion. Am J Physiol Cell Physiol, 286: 1009-1017, 2004.

Toledo A, Yamaguchi J, Wang J-Y, Bass BL, Turner DJ, Strauch ED:  Taurodeoxycholate Stimulates Intestinal Cell Proliferation and Protects Against Apoptotic Cell Death through Activation of NFκB. Dig Dig Dis Sci, 49:1664-1671, 2004.

Zhang HM, Keledjian KM, Rao JN, Zou T, Liu L, Marasa BS, Wang SR, Ru L, Strauch ED, Wang JY.Induced focal adhesion kinase expression suppresses apoptosis by activating NF-κB signaling in intestinal epithelial cells. Am J Physiol Cell Physiol. 2006 May; 290(5):C1310-20.

Alaish SM, Strauch ED The use of Alloderm in the closure of a giant omphalocele. J Pediatr Surg. 2006 Mar;41(3):e37-9.

Jen HC, Graber J, Hill JL, Alaish SM, Voigt RW, Strauch ED: Surgical necrotizing enterocolitis and intraventricular hemorrhage in premature infants under 1000 grams. J Peds Surg, 2006.

Turner DJ, Alaish SM, Zou T, Rao, JN, Wang J-Y, and Strauch ED. Bile salts induce resistance to apoptosis through NF-κB-mediated XIAP expression. Ann Surg 245(3): 415-25, 2007.

Turner DJ, Martin PC, Rao JN, Greenspon J, Zou T, Bass BL, Wang J-Y, and Strauch ED. Substance P regulates migration in rat intestinal epithelial cells. Ann Surg  Mar; 245(3): 408-14, 2007.

Greenspon J, Li R, Xiao L, Rao JN, Marasa BS, Strauch ED, Wang JY, Turner DJ.  Sphingosine-1-phosphate protects intestinal epithelial cells from apoptosis through the Akt signaling pathway. Dig Dis Sci. 2009 Mar;54(3):499-510.

Alaish SM, Greenspon J, Strauch ED, Sun CC. Intraabdominal pulmonary sequestration presenting with elevated urinary normetanephrine levels.  J Pediatr Surg. 2009 Mar;44(3):e11.