Personal History
Dr. Shamoo is a professor and former chairman of the Department of Biochemistry and Molecular Biology, and holds a secondary appointment to the Department of Epidemiology and Preventive Medicine. He serves as a member of the Defense Health Board (DHB), chairing the Medical Ethics Subcommittee as well as a being a member of its Executive Committee. Dr. Shamoo is a senior analyst for Foreign Policy in Focus, of the Institute for Policy Studies. He is the founder and Editor-in-Chief of the journal, Accountability in Research and is on the editorial board of the Drug Information Journal.
Writing frequently in newspapers and websites on ethics and public policy, Dr. Shamoo's opinion editorials have appeared frequently in major newspapers including the Christian Science Monitor and the The Baltimore Sun. Dr. Shamoo has been cited and has appeared frequently in local and national media including CBS' 48 hours, Newsweek and National Public Radio (NPR).
Shamoo was a member of the National Human Research Protections Advisory Committee (NHRPAC). In 2003, he chaired a Special Issue GlaxoSmithKline Pharmaceuticals Ethics Advisory Group. Shamoo was appointed to the Armed Forces Epidemiological Board (AFEB) of the Department of Defense as the ethics consultant and as a member. In 2006, he was appointed to the Maryland Governor's Higher Education Transition Working Group.
Since 1994, Shamoo has been teaching a graduate course on, "Responsible Conduct of Research". He has chaired twelve international conferences on ethics in research and human research protections and testified on this issue before Congressional Committees and the National Bioethics Advisory Commission. He chaired the Ethics and Regulatory Forum of the Association of Clinical Research Professionals (ACRP). In 1995, he co-founded the human rights organization, Citizens for Responsible are and Research (CIRCARE).
Dr. Shamoo has lectured worldwide on topics ranging from issues in biochemistry to ethics, science and public policy. He has held visiting professorships at notable institutions, including Sarah Lawrence College and the Institute for Political Studies in Paris, France and L'aquila University, Italy. Dr. Shamoo provides consultation, training, education, and workshops on Human Research Protections (HRP), and Responsible Conduct in Research (RCR) to Institutional Review Boards (IRBs) and their members as well as to other members of the profession.
Dr. Shamoo has authored, co-authored, or edited fifteen books, including his textbook , Responsible Conduct of Research (with David Resnick, 2003, 2009); Ethics of the Use of Human Subjects in Research (with Felix Gyi, 2002). He has published over 270 papers.
Dr. Shamoo has held full-time faculty appointments at East Carolina University, NIH, University of Rochester School of Medicine & Dentistry, Max-Planck Institute for Biophysics, Frankfort, West Germany, Mount Sinai School of Medicine of the City University of New York, and University of Louisville.
Publications
Selected Publications (see CV for complete list)
Shamoo, A. E., 2008. "The Myth of Equipoise in Phase 1 Clinical Trials", Medscape J Med. 2008;10(11):254. 2008 Medscape, Posted 11/05/2008 at http://www.medscape.com/viewarticle/582554.
Amin, S. B., McDermott, M. P., and Shamoo, A. E. 2008. "Clinical Trials of Drugs Used Off-Label in Neonates: Ethical Issues and Alternative Study Designs", Accountability in Research, 15:168-187.
Shamoo, A. E. and Katzel, L.I., 2008. "How Should Adverse Events Be Reported in US Clinical Trials?: Ethical Considerations", Clinical Pharmacology & Therapeutics, 27 Feb 2008), doi: 10.1038/clpt.2008.14, Ethics
Shamoo, A. E., and Schwartz, J. 2007. "Universal and Uniform Protections of Human Subjects in Research", American Journal of Bioethics, 7(12): 7-9.
Shamoo, A. E., and Woeckner, E. 2007. "Ethical Flaws in the TeGenero Trial", The American Journal of Bioethics, 7:2, 90 - 92. To link to this article: DOI: 10.1080/15265160601112204; URL: http://dx.doi.org/10.1080/15265160601112204
Silverman, H. et al (…Shamoo, A. E.,…), 2006. "Enhancing Research Ethics Committees in Egypt - Guidelines for Standard Operating Procedures", Monitor, Dec, 2005, 49 – 52, and Appendix, A1 - A17.
Shamoo, A. E., and Resnik, D. B., (2006), "Ethical Issues for Clinical Research Managers", Drug Information Journal, 40: 371-383.
Shamoo, A. E. (2006), "Letter to the Editor: Emergency Research Consent Waiver – A Proper Way", American Journal of Bioethics, 6(4): W48 – W51.
Shamoo, A. E. and Resnik, D. B. (2006), "Strategies to Minimize Risks and Exploitation in Phase One Trials on Healthy Subjects", American Journal of Bioethics, 6(3): W1 – W13.
Shamoo, A. E. (2005), "Accountability in Research," In: Encyclopedia of Science, Technology, and Ethics, edited by Carl Mitcham, Thompson - Gale Company.
Shamoo, A. E. (June, 2005), "Debating Moral Issues in Developing Countries", Applied Clinical Trials (actmagazine.com), 14(6):86-96.
Shamoo, A. E. (2005), "The Need for Better Reporting of Adverse Events for Human Subjects in Research", DIA Today, April 2005, Volume 5, Issue 2, p. 18, 20.
Resnik, D. B. and Shamoo, A. E., (2005) "Bioterrrorism and the Responsible Conduct of Research", Commentary, Drug Development Research, 63:121-133.
Shamoo, A. E. and Cole, J. (2004), "Ethics of Genetic Modification of Behaviour", Accountability in Research, 11:201-214.
Shamoo, A. E. and Strause, L. (2004) "Closing the Gap in Regulations for the Protection of Human subjects in Research", Monitor, Spring 2004, chosen as cover story.
Shamoo, A. E. and Moreno, J. (2004) "A Response to Commentators on “Ethics of Research Involving Mandatory Drug Testing of High School Athletes in Oregon", American Journal of Bioethics 4:W 29.
Shamoo, A.E. and Moreno, J. (2004), "Ethics of Research Involving Mandatory Drug Testing of High School Athletes in Oregon," American Journal of Bioethics 4:25-31, (Chosen as a Target Article with 13 commentaries).
Shamoo, A.E., and Cole, J.W. (2004), "Fear of Influence - Conflict of Interest in Biomedical and Genetic Research," In: GenWatch 13:12-13, July-August (Both in the magazine and website).
Shamoo, A.E., and Campbell, J. D., (2003), "The Use of Experimental Drugs During National Crises," Accountability in Research, 10:69-84, 2003.
Shamoo, A.E., and Tauer, C.A. (2002), "Ethically Questionable Research with Children: The Fenfluramine Study," Accountability in Research, 9:143-166,2002.
Resnik, D., and Shamoo, A.E., 2002. Conflict of Interest and the university, Accountability in Research, 9: 45- 64.
Shamoo, A.E. (2002), "Ethically Questionable Research with Children. The Kennedy Krieger Lead Abatement Study," Accountability in Research, 9:167-175, 2002.
Shamoo, A.E. (2001), "Adverse Events Reporting – The Tip of an Iceberg," Accountability in Research, 8:197-218.
Shamoo, A. E. and Cheryl Dunigan (2000), "Ethics in Research”, Experimental Biology and Medicine 224:205-210.
Sharav, V. H., and Shamoo, A. E. (2000), "Are Experiments That Chemically Induce Psychosis In Patients Ethical?", BioLaw, II, No.1: S1-S36.
Shamoo, A.E. (1999), "Critique of the Recommendations of the National Bioethics Advisory Commission's Report on Research Involving Persons with Mental Disorders That May Affect Decisionmaking Capacity," BioLaw II, Nos. 9 & 10:S439-S444.
Shamoo, A.E. (1999). "Institutional Review Boards (IRBs) and Conflict of Interest," Accountability in Research 7:201-212.
