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Jerimy C. Polf
View Curriculum Vitae 

Jerimy C. Polf Ph.D.

Academic Title: Associate Professor
Primary Appointment: Radiation Oncology
Location: Maryland Proton Therapy Center
Phone: 410-369-5314
Fax: 410-328-2618

Personal History:

Dr. Jerimy Polf received his PhD and completed his postdoctoral fellowship from Oklahoma State University. Dr. Polf came to the University of Maryland School of Medicine in 2013 from the University of Texas, MD Anderson Cancer Center, in Houston.

Research Interests:

Dr. Polf research interests include Proton Beam Radiotherapy, Prompt Gamma Imaging, Proton Beam Range Verification, Prompt Gamma Spectroscopy, and Radiobiology.

Clinical Speciality:

Proton radiotherapy


09/25/15-7/34/20 NIH/NCI R01 CA187416-01A1
"Prompt Gamma Imaging for in vivo range verification during proton radiotherapy"

2014 Radiation Oncology Seed Grant, University of Maryland School of Medicine
Co-PI: Jerimy Polf (co-PI: Isabel Jackson)
"Targeted release of liposome encapsulated cancer treatment agents using radiotherapy"

NIH/NCI R21 CA137362-01A2
PI: Jerimy Polf
"Real-time dose and tissue imaging during proton beam irradiation"

American Cancer Society, IRG-08-061-01
PI: Jerimy Polf
"Imaging tumor hypoxia with proton beam radiotherapy"

Oklahoma State University Center for Veterinary Health Sciences
Co-Inv: Jerimy Polf (PI: Ashish Ranjan)
"Targeting solid tumor by combining Proton Beam Radiotherapy (PBRT) and drug encapsulated thermosensitive liposomal nanoplatforms"


Book Chapters

Polf JC, Depauw N, and Seco J, Monte Carlo applications in prompt gamma imaging and proton radiography in proton radiotherapy.  In Monte Carlo Techniques in Radiotherapy, 1st Edition, Imaging in Medical Diagnosis and Therapy Series, CRC Press, Fall 2012.

Selected Recent Journal Articles

Akselrod MS, Lucas AC, Polf JC, McKeever SWS. Optically Stimulated Luminescence in A1203. Radiat Prot Dosimetry 29:391-399, 1998.

McKeever SWS, Akselrod MS, Colyott LE, Agersnap-Larsen N, Polf JC, Whitley VH. Characterization of A1203 for use in Thermally Stimulated and Optically Stimulated Luminsescence Dosimetry. Radiat Prot Dosimetry 84:163-168, 1999.

Polf JC, McKeever SW, Akselrod MS, Holmstrom S. A real-time, fibre optic dosimetry system using A1203 fibres. Radiat Prot Dosimetry 100(1-4):301-4, 2002.

Bloom D, Evans DR, Holmstrom S, Polf JC, McKeever SWS, Whitley VH. Characterization of A1203 Single Crystals Grown by the Laser-Heated Pedestal Growth Technique for Potential Use in Radiation Dosimetry. Rad Meas 37(2):141-149, 2003.

Whitley VH, Yukihara EG, Polf JC, Klein D, McKeever SWS, Akselrod AE, Akselrod MS. The effects of deep trap population on the Thermoluminescence of A1203:C. Rad Meas 37:627-638, 2003.

Polf JC, Yukihara EG, Akselrod MS, McKeever SWS. Real-time luminescence from A1203 fiber dosimeters. Rad Meas 38:227-240, 2004.

Polf JC, Newhauser WD. Calculations of neutron dose equivalent exposures from range-modulated proton therapy beams. Phys Med Biol 50(16):3859-73, 8/2005.

Ciangaru G, Polf JC, Bues M, Smith AR. Benchmarking analytical calculations of proton doses in heterogeneous matter. Med Phys 32(12):3511-23, 12/2005.

Polf JC, Newhauser WD, Titt U. Patient neutron dose equivalent exposures outside of the proton therapy treatment field. Radiat Prot Dosimetry 115(1-4):154-8, 2005.

Polf JC, Harvey MC, Titt U, Newhauser WD, Smith AR. Initial beam size study for passive scatter proton therapy. I. Monte Carlo verification. Med Phys 34(11):4213-8, 11/2007.

Polf JC, Harvey MC, Smith AR. Initial beam size study for passive scatter proton therapy. II. Changes in delivered depth dose profiles. Med Phys 34(11):4219-22, 11/2007.

Newhauser W, Fontenot J, Zheng Y, Polf J, Titt U, Koch N, Zhang X, Mohan R. Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm. Phys Med Biol 52(15):4569-4584, 2007.

Archambault L, Polf JC, Beaulieu L, Beddar S. Characterizing the response of miniature scintillation detectors when irradiated with proton beams. Phys Med Biol 53(7):1865-76, 4/7/2008.

Harvey MC, Polf JC, Smith AR, Mohan R. Feasibility studies of a passive scatter proton therapy nozzle without a range modulator wheel. Med Phys 35(6):2243-2252, 6/2008.

Titt U, Sahoo N, Ding X, Zheng Y, Newhauser W, Zhu X, Polf JC, Gillin MT, Mohan R. Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions. Phys Med Biol 53(16):4455-4470, 7/2008.

Polf JC, Peterson S, Ciangaru G, Gillin M, Beddar A. Prompt gamma-ray emission from biological tissues during proton irradiation: a preliminary study. Phys Med Biol 54(3):731-743, 1/2009.

Kry SF, Howell RM, Polf JC, Mohan R, Vassiliev ON. Treatment vault shielding for a flattening filter free medical linear accelerator. Phys Med Biol 54(5):1265-1273, 2/2009,

Peterson S, Polf JC, Ciangaru G, Bues M, Beddar S, Smith A. Experimental validation of a monte carlo proton therapy nozzle model incorporating magnetically steered protons. Phys Med Biol 54(10):3217-3229, 5/2009.

Peterson SW, Polf JC, Ciangaru C, Frank SJ, Bues M, Smith AR. Variations in proton scanned beam dose delivery due to uncertainties in magnetic beam steering. Med. Phys. 36(8):3693-3702, 7/2009.

Polf JC, Peterson SW, McCleskey M, Roeder BT, Spiridon A, Beddar S, Trache L. Measurement and calculation of characteristic prompt gamma ray spectra emitted during proton irradiation. Phys Med Biol 54(11):N519-N527, 11/2009.

Peterson SW, Robertson D, Polf JC, Optimizing a three-stage Compton camera for measuring prompt gamma rays during proton irradiation, Phys Med Biol 55(11):6841-6856, 11/2010.

Polf JC, Bronk L, Driessen W, Arap W, Pasqualini, R. Gillin, M., Enahnced Relative biological effectiveness of proton radiotherapy in tumor cells with internalized gold nanoparticles. Appl Phys Letters 98:193702(1-3), 2011.

Robertson D, Polf JC, Peterson SW, Giffin M, Beddar S. Material efficiency studies for a Compton camera specifically designed for measuring prompt gamma rays emitted during proton radiotherapy. Phys Med Biol 56:3047-3059, 2011.

Wootton L, Polf JC, Peterson S, Wilkinson J, Rozner MA, Baiter PA, Beddar S. Proton dose perturbations caused by high-voltage leads from implanted cardioverter defibrillators. J Appl Clin Med Phys. In Press, 2012.

Mackin D, Peterson SW, Beddar S, Polf JC, Evaluation of a stochastic reconstruction algorithm for use in Compton camera imaging and beam range verification from secondary gamma emission during proton therapy, Phys Med Biol 57:3537-3553, 2012.

Mackin D, Polf JC, Peterson SW, Beddar S, Measurement of Doppler broadening and detector resolution effects on the performance of 3-stage Compton cameras, Med Phys, 40(1):012402, 2013.

Polf JC, Panthi R, Mackin DS, McCleskey M, Saastamoinen A, Roeder BT and Beddar S, Measurement of characteristic prompt gamma rays emitted from oxygen and carbon in tissue-equivalent samples during proton beam irradiation, Phys Med Biol, 58(17):5821-5831, 2013.

Senavirathna, LK, Fernando R, Maples D, Zheng, Y, Polf JC, Ranjan A, Tumor spheroids as an in vitro model for determining the therapeutic response to proton beam radiotherapy and thermally sensitive nanocarriers, Theranostics 3(9):687-691, 2013.

Polf JC, Mackin DS, Lee E, Avery S, and Beddar S, Detecting prompt gamma emission during proton therapy: the effects of detector size and distance from the patient, Phys Med Biol, 59:2325-2340, 2014.

Fernando R, Maples D, Senavirathna LK, Zheng Y, Polf JC, Bartels KE, Piao D, and Ranjan A, Hyperthermia sensitization and proton beam triggered liposomal drug release for targeted tumor therapy, Pharm Res, 31, PMID: 24852892, (Epub: May 23) 2014.

Lee E, Polf JC, Mackin DS, Beddar S, Dolney D, Ainsley C, Kassaee A, Avery S. Study of the Angular Dependence of a Prompt Gamma Detector Response during Proton Radiation Therapy. Int J Particle Ther., 1(3):731-744, 2014.

McCleskey M, Kaye W, Mackin DS, Beddar S, He Z, Polf JC, Evaluation of a multistage CdZnTe Compton camera for prompt ¿ imaging for proton therapy, Nucl. Instrum. And Meth A, 785:163-169, 2015.

Polf JC, Avery S, Mackin D and Beddar S, Imaging of prompt gamma rays emitted during delivery of clinical proton beams with a Compton camera: feasibility studies for range verification, Phys. Med. Biol. 60:7085-7099, 2015.

Polf JC and Parodi K, In vivo range monitoring with secondary emission for ion beam radiotherapy, Physics Today, 68(10):28-33, 2015.

Polf JC, Chuong M, Zhang B, Mehta M, Anterior-oriented beam arrangements with daily in vivo range verification for proton therapy of prostate cancer: Rectal toxicity rates, Int J Particle Ther, 2 (EPub:09/29/2015), DOI: 10.14338/IJPT-15-00015.1, 2015.