Casey Lynnette Overby is an Assistant Professor in the Program for Personalized and Genomic Medicine (PPGM) and a member of the Center for Health-related Informatics and Bio-imaging (CHIB) at the University of Maryland. She received a Bachelor of Science degree in Bioinformatics from the University of Michigan in 2004, her Masters of Biotechnology from the University of Pennsylvania in 2006, and her PhD in Biomedical and Health Informatics from the University of Washington School of Medicine in 2011. She also received a Graduate Certificate in Public Health Genetics from the University of Washington School of Public Health in 2011. In 2013, Dr. Overby completed her post-doctoral training in the Department of Biomedical informatics at Columbia University and started her position at the University of Maryland.
My research is at the intersection of translational bioinformatics and implementation science. I seek to develop new approaches for interpreting genome information and to understand processes and factors associated with the successful integration of these approaches into healthcare settings. I also seek to understand factors associated with the successful integration of approaches that support use of new evidence for clinical and shared decision-making.
Overby CL, Tarczy-Hornoch P, Demner-Fushman D. The Potential for Automated Question Answering in the Context of Genomic Medicine: An Assessment of Existing Resources and Properties of Answers. BMC Bioinformatics. 2009 Sept 17; 10 Supp 9:S8 (Presented at 2009 AMIA Summit on Translational Bioinformatics)
Overby CL, Tarczy-Hornoch P, Hoath J, Kalet I, Veenstra D. Feasibility of Incorporating Genomic Knowledge Into Electronic Medical Records for Pharmacogenomic Clinical Decision Support. BMC Bioinformatics. 2010 Oct 28; 11 Supp 9:S10 (Presented at 2010 AMIA Summit on Translational Bioinformatics)
Hachad H, Overby CL, Argon S, Keung C, Ragueneau-Majlessi I, Levy RH. ePKGene: a knowledge-based tool for analyzing the impact of genetics on drug exposure. Human Genomics. 2011 Jul 1; 5(5):506-515.
Overby CL, Devine EB, Tarczy-Hornoch P, Kalet I. Deriving Rules and Assertions From Pharmacogenomic Knowledge Resources In Support of Patient Drug Exposure Predictions. Journal of the American Medical Informatics Association. 2012; 19(5):840-850.
Overby CL*, Tarczy-Hornoch P*, Kalet I, Thummel K, Smith J, Del Fiol G, Fenstermacher D, Devine EB. Development of a prototype model for integrating pharmacogenomics findings into clinical practice. Journal of Personalized Medicine. 2012; 2(4):241-256. (*indicates co-first author).
Gottesman O, Scott SA, Ellis SB, Overby CL, Ludtke A, Hulot J, Hall J, Chatani K, Myers K, Kannry JL, Bottinger EP, The CLIPMERGE PGx Program: Clinical Implementation of Personalized Medicine through Electronic Health Records and Genomics – Pharmacogenomics, Clinical Pharmacology & Therapeutics accepted article preview online 3 April 2013; doi:10.1038/clpt.2013.72
Overby CL, Tarczy-Hornoch P. Personalized Medicine: Challenges and Opportunities for Translational Bioinformatics. Personalized Medicine. 2013; 10(4);453-462.
Overby CL. Pathak J, Gottesman O, Haerian K, Perotte A, Murphy S, Bruce K, Johnson S, Talwalker J, Shen Y, Ellis S, Kullo I, Chute C, Friedman C, Bottinger E, Hripcsak G, Weng C. A Collaborative Approach to Develop an Electronic Health Record Phenotyping Algorithm for Drug-Induced Liver Injury. Journal of the American Medical Informatics Association. Published Online First: 9 July 2013. doi:10.1136/amiajnl-2013-001930
Overby CL, Chung WK, Hripcsak G, Kukafka R. Cancer Genetic Counselor Information Needs for Risk Communication: A Qualitative Evaluation of Interview Transcripts. Journal of Personalized Medicine. 2013; 3(3):238-250.
Del Fiol G, Curtis C, Cimino JJ, Iskander A, Kalluri ASD, Jing X, Hulse NC, Long J, Overby CL, Schardt C, Douglas DM. Disseminating Context-Specific Access to Online Knowledge Resources within Electronic Health Record Systems. Studies in Health Technology and Informatics. 2013; 192:672-6.
Overby CL*, Kohane I*, Williams MS, Kannry J, Starren JB, Bottinger E, Gottesman O, Denny JC, Weng C, Tarczy-Hornoch P, Hripcsak G. Opportunities for Genomic Clinical Decision Support Interventions. Genetics in Medicine. 2013.
Lau B, Overby CL, Wirtz HS, Devine EB. The Association between Use of a Clinical Decision Support Tool and Adherence to Monitoring for Medication-Laboratory Guidelines in the Ambulatory Setting. Applied Clinical Informatics. 2013 (in press).
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