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Lab Techniques and Equipment
Flow Sorting Core Facility
Publications
Noriko Sato, Helen Sabzevari, Song Fu, Wei Ju, Michael N. Petrus, Richard N. Bamford, Thomas A. Waldmann and Yutaka Tagaya. Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15 transgenic mice requires the cis-expression of IL-15Ralpha. Blood (in press)Fumi Miyagawa, Yutaka Tagaya, Brian S Kim, Hiral J Patel, Kazuto Ishida , Toshiaki Ohteki, Thomas A Waldmann , and Stephen I Katz. IL-15 serves as a co-stimulator in determining the activity of autoreactive CD8 Tcells in an experimental mouse model of graft vs. host like disease. J. Immunol. 2008 181: 1109-19
Noriko Sato, Hiral J. Patel, Thomas A. Waldmann, and Yutaka Tagaya The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 T cells. Proc. Natl. Acad. Sci. USA 2007 104: 588-593
Hisataka Kobayashi, Sigrid Dubois, Noriko Sato, Helen Sabzevari, Yoshio Sakai, Thomas A. Waldmann, and Yutaka Tagaya. The role of trans-cellular IL-15-presentation in the activation of NK-mediated killing, which leads to enhanced tumor immunesurveillance Blood, 2005 105: 721 - 727
Sigrid Dubois, Jennifer Mariner, Thomas A. Waldmann, and Yutaka Tagaya. IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells. Immunity 2002 17: 537-547
Joanna Marks-Konczalik, Sigrid Dubois, Helen Sabzevari, Nobuo Yamada, Lionel Feigenbaum, Thomas A. Waldmann, and Yutaka Tagaya. IL-2 induced activation-induced cell death is inhibited in IL-15 Transgenic mice. Proc. Natl. Acad. Sci. 2000 97:11445-11450
Kouetsu Ogasawara, Shigeaki Hida, Nazli Azimi, Yutaka Tagaya, Takeo Sato, Taeko Yokochi-Fukuda, Thomas A. Waldmann, Tadatsugu Taniguchi, and Shinsuke Taki (1998) Requirement for IRF-1 in the microenvironment development of natural killer cells. Nature 391: 700-703
Yutaka Tagaya, Jack D. Burton, Yoshihisa Miyamoto, and Thomas A. Waldmann. (1996) Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells. EMBO J. 15: 4928-4939.
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