Research Interests:Examines secondary injury processes following traumatic spinal cord injury (SCI) and pharmacological/gene therapeutic interventions for SCI. More specifically, studies the pathophysiological role of cell cycle activation in SCI using complementary genetic and pharmacological strategies. Also studies nocifensive behaviors and central pain regulation after experimental SCI, and the role of mitochondrial DNA in cell death.
Wu J, Yoo S, Wilcock D, Lytle JM, Leung PY, Colton CA, Wrathall JR (2010) Interaction of NG2+ glial progenitors and microglia/macrophages from the injured spinal cord. GLIA, 58(4): 410-422.
Wu J#, Wrathall JR, Schachner M# (2010) Phosphatidylinositol 3-kinase/protein kinase Cδ activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocyte. GLIA, 58(3): 315-328.
Wu J#, Leung PY, Sharp A, Lee HJ, Wrathall JR (2011) Increased expression of the close homolog of the adhesion molecule L1 (CHL1) in different cell types over time after rat spinal cord contusion. Journal of Neuroscience Research, 89(5): 628-638.
Wu J#, Stoica B, Faden AI (2011) Cell cycle activation and spinal cord injury. Neurotherapeutics, 8(2): 221-228.
Faculty members: Update your contact information and create a profile.