Dr. Adebamowo’s education includes training in medicine, surgery, oncology and epidemiology. In 1984 he received his MB ChB Hons from the University of Jos in Nigeria, after which he completed post-graduate training in surgery at the University College Hospital in Ibadan, Nigeria. In 2004 he earned a doctorate in Nutrition Epidemiology with a minor in Biostatistics from Harvard School of Public Health, Boston.
Before coming to the University of Maryland, Dr. Adebamowo worked as a professor of surgery, lecturer in nutrition epidemiology and bioethics, and Director of the Institute for Advanced Medical Research and Training at the University of Ibadan in Nigeria, and as the Director of the West African Bioethics Training Program, also in Ibadan, Nigeria.
Dr. Adebamowo currently is an Associate Professor in the Division of Cancer Epidemiology, Department of Epidemiology and Public Health and a member of the Greenebaum Cancer Center at the University of Maryland, Baltimore School of Medicine. He also serves as Director of the Center for Bioethics in Ibadan, Nigeria; Director of the West African Framework Program for Global Health; Director of the Nigerian National System of Cancer Registries and Chairman of the National Health Research Ethics Committee of Nigeria.
Host germline, somatic, and HPV genomics and Cervical cancer risk in African women
Dr. Adebamowo works with partner institutions in Nigeria and Zambia to implement research studies in viral oncology that are exploring the role of Human Papilloma Virus in cervical, and head and neck cancers. In Nigeria, he has:
- Established a systematic cervical cancer screening program in Nigeria and is collaborating with others in an effort to cover 70% of Nigeria’s 80 million women with at least once in a lifetime cervical cancer screening program;
- Built an HPV, vaginal microenvironment and cervical cancer risk research program that has already contributed to the identification of an association between Lactobacillus iners rich vaginal microbiota, specific human genetic variations, and prevalent high risk cervical HPV infection. This has implications for improved understanding of the host and vaginal microenvironment’s role in cervical carcinogenesis as well as for risk stratification in cervical cancer and understanding of disparities in HPV infection and cervical cancer in the United States;
- Continued to characterize the pattern of persistent high risk HPV infection which supports studies of the epidemiology and secular trend in high risk HPV infection. This is linked to a nation-wide cancer registration system that tracks incidence of cancers including those associated with HPV infection – Head and Neck, Anal and Cervical cancers. So far these studies have demonstrated that the pattern of prevalent high risk HPV infection in Africa may be different from other parts of the world, which may affect efficacy of currently available HPV vaccines.
These research formed the foundation projects for the African Collaborative Center for Microbiome and Genomics Research – an H3Africa funded collaborative center at the Institute of Human Virology, Nigeria.
Obesity, Nutrition and Physical Activity
In recognition of the role of obesity as the major predictor of mortality and morbidity in the world today and the second most important risk factor for cancer in Sub-Saharan Africa, Dr. Adebamowo’s group is studying nutrition, obesity and physical activity epidemiology in Nigeria, including the development and validation of the Nigerian Food Frequency Questionnaire and Food Composition Database.
In collaboration with colleagues at the Harvard School of Public Health (HSPH), Dr. Adebamowo’s group is working on dietary substitution to reduce intake of energy dense, low fiber foods in Nigeria as part of the GNET initiative.
A second collaboration with HSPH is focused on developing a large prospective cohort of 500,000 Africans for non-communicable diseases (NCD) research and training in Africa called PaCT. The objective of this program is to identify risk factors for the emerging epidemic of NCD in Africa, conduct multi-country comparison studies and train a generation of African researchers/scientists.
Dr. Adebamowo is co-PI of a Wellcome Trust funded H3Africa Collaborative research project spanning 12 African countries and focused on the environmental and genetic risk of Diabetes Mellitus in Sub-Saharan Africa.
Nigerian National System of Cancer Registration
Clement has also worked with the Nigerian government to resuscitate the Nigerian National System of Cancer Registration which has successfully returned Nigerian data to the magisterial Cancer in Five Continents publication of the World Health Organization and International Agency for Research against Cancer after more than 30 years of absence. Given that Nigeria constitutes ~20% of Africa’s population, this significantly changes the proportion of Africans who are covered by a population based cancer registration system.
In addition to the generation of incidence data on cancer in Nigeria, the NSCR has become a regional hub for training and capacity development for cancer registries in West Africa and is a member of the African Network of Cancer Registries.
The cancer registration project is also collaborating in using Geospatial mapping to study cancer incidence in Nigeria and linkage research of HIV and Cancer registries databases to improve the epidemiology of AIDS Associated Cancers in Africa.
Nigerian National Health Research Ethics Committee
Since 2005, Dr. Adebamowo has led the West African Bioethics Training program to work in partnership with regional bioethicists, research institutions, teaching hospitals, universities, international NGOs and governments to develop the Nigerian National Health Research Ethics Committee and several institutional research ethics committees. He also led the effort to create a National Health Research Ethics Code for Nigeria and is currently developing additional infrastructure to strengthen health research ethics review in the country through mentoring, training and development of additional guidelines for vulnerable populations, a system of confidential certification and electronic ethics review system. The overall goal is to promote the highest ethical and scientific standard in research and enable international collaborative research.
Dr. Adebamowo has a deep and abiding interest in training and capacity development, especially of young scientists in Africa. He is a leader in use of video conferencing facilities at IHVN, Abuja Nigeria and the NIH/FIC supported Elluminate web conferencing facilities to teach a wide range of topics to students throughout Nigeria. As PI of 3 NIH training grants, Dr. Adebamowo has supported the training of faculty, scientists and physicians from several institutions in Nigeria in cancer registration, cancer epidemiology, life-course epidemiology, quantitative and qualitative research methods, use of the case-method to teach NCD epidemiology, genetics and epigenetics. This teaching portfolio continues to increase as demands arise for knowledge and new capacity from collaborating institutions.
11 most recent publications:
- HOU N., OGUNDIRAN O., OJENGBEDE O., MORHASON-BELLO I., ZHENG Y., FACKENTHAL J., ADEBAMOWO C., ANETOR I., AKINLEYE S., OLOPADE O., HUO D. Risk Factors for Pregnancy-Associated Breast Cancer: A Report from the Nigerian Breast Cancer Study. Annals of Epidemiology 2013 Jul 20. Pii:S1047-2797(13)00171-3. Epub ahead of print.
- FAMOOTO A., ALMUJTABA M., DARENG E., AKAROLO-ANTHONY S., OGBONNA C., OFFIONG R., OLANIYAN O., WHEELER C.M., DOUMATEY A., ROTIMI C. N., ADEYEMO A., ADEBAMOWO C. A. RPS19 and TYMS SNPs and Prevalent High Risk Human Papilloma Virus Infection in Nigerian women. PLoS One 2013 Jun 27;8(6):e66930. Print 2013.
- UZOMA ONONOGBU, MARYAM ALMUJTABA, ZAHRA MODIBBO, ISHAK LAWAL, RICHARD OFFIONG, OLAYINKA OLANIYAN, PATRICK DAKUM, DONNA SPIEGELMAN, WILLIAM BLATTNER AND CLEMENT ADEBAMOWO Cervical Cancer Risk Factors among HIV-Infected Nigerian women BMC Public Health 2013 Jun 14;13:582.
- AKAROLO-ANTHONY S., ODUBORE F. YILME S., ARAGBADA O., ODONYE G., HU F. B., WILLETT W., SPIEGELMAN D., ADEBAMOWO A. C. Pattern of dietary carbohydrate intake among urbanized adult Nigerians. Inter. J. Food Sci. Nutr, 2013 May;64(3):292-9
- OGUNRIN O., OGUNDIRAN T. O., ADEBAMOWO C. Development and pilot testing of an online module for ethics education based on the Nigerian National Code for Health Research Ethics. BMC Medical Ethics 2013 Jan 2;14:1.
- ADELEYE O., ADEBAMOWO C. A. Factors Associated with Research Wrongdoing in Nigeria. J Empir. Res. Hum. Res. Ethics. 2012 Dec;7(5):15-24
- JEDY-AGBA E. E., ADEBAMOWO C. A. Knowledge, Attitudes and Practices of AIDS Associated Malignancies among People Living with HIV in Nigeria. Infectious Agents and Cancer 2012 Oct 25; 7(1):28.
- IGBE M., ADEBAMOWO C. A. Qualitative study of knowledge and attitudes to biobanking among lay persons in Nigeria. BMC Medical Ethics 2012 Oct 16;13:27.
- DOUMATEY A. P., ZHOU J., HUANG H., ADELEYE J., BALOGUN W., FASANMADE O., JOHNSON T., OLI J., OKAFOR G., AMOAH A., EGHAN B., AGYENIM-BOATENG K., ACHEAMPONG J., ADEBAMOWO C., ADEYEMO A., ROTIMI C. N. Circulating adiponectin is associated with renal function independent of age and serum lipids in West Africans. Int. J. Nephrol. 2012;2012:730920
- BENTLEY A. R., DOUMATEY A. P., CHEN G., HUANG H., ZHOU J., SHRINER D., JIANG C., ZHANG Z., LIU G., FASANMADE O., JOHNSON T., OLI J. M., OKAFOR G., EGHAN B., AGYENIM-BOATENG K., ADELEYE J., BALOGUN W., ADEBAMOWO C., AMOAH A., ACHAEMPONG J., ADEYEMO A., ROTIMI C. Variation in APOL1 contributes to Ancestry-level differences in HDLc-kidney function association. International Journal of Nephrology 2012;2012:748984.
- AKAROLO-ANTHONY S., ADEBAMOWO C. A. Physical activity, BMI and cancer prevention in urban adults. BMC Proceedings 2012 6(Suppl 3):P69.
Links of Interest:IHV Nigeria
Dr. Adebamowo’s personal site
Society of Oncology and Cancer Research of Nigeria (SOCRON)
National Health Research Ethics Committee, Nigeria
West African Bioethics
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