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Henry I.C.  Lowe
 

Henry I.C. Lowe Ph.D.

Academic Title: Adjunct Professor
Primary Appointment: Medicine
lowebiotech@gmail.com
Location: BIO, S307
Phone: 561-568-1524
Fax: 561-333-3472
 

Personal History:

Professor the Honourable Henry I.C. Lowe, an Ethno-Medicinal Chemist, has contributed approximately 50 years in the fields of science and technology, particularly in the health science nationally, regionally and internationally. As a result of his outstanding work in these areas he has earned several recognitions nationally and internationally, including the recent Order of Jamaica in August 2012 and Commander of the Order of Distinction in Science in 1982. He has also served on several public and private sector boards. Dr. Lowe is not only recognized as one of the regions outstanding scientists but also public servant, author, educator and successful entrepreneur.

Dr. Lowe was born in St. Andrew, Jamaica and was educated at Calabar and Excelsior High Schools, University of the West Indies, (B.Sc. Hons.), University of Sydney, (M.Sc.), Manchester University, (Ph.D.), Bolton Institute of Technology England, (Dip. Technical Education), Harvard University and M.I.T, U.S.A.

A former Permanent Secretary for the Government of Jamaica, Dr. Lowe researched and established the first Ministry of Science & Environment in the CARICOM region. He served as Chairman as well as President & CEO of Blue Cross of Jamaica. Dr. Lowe is founder and Executive Chairman of the EHF Group of Companies, which includes a private, not for profit organization, Environmental Health Foundation (EHF), established in 1992, to enhance the quality of people’s lives in Jamaica. The Group also includes a commercial entity, EHF Resource Development Limited. This company has subsidiaries including Pelican Publishers Limited (a boutique publishing house with an emphasis on health related publications), Eden Gardens Wellness Resort & Spa (a premier wellness & lifestyle centre), Bio-Tech R&D Institute (a company engaged in the research, development and commercialization of health and wellness products from Jamaican plant-based materials) and Medicanja (a company founded to develop the medical marijuana industry in Jamaica). Dr. Lowe established the first Nutraceutical industry in the Caricom region with significant financial potential for import substitution and the export market, which is a multibillion marketplace.

Dr. Lowe has discovered several bioactive molecules from Jamaican medicinal plants (particularly Jamaican Ball Moss) which are being developed for cancer therapy, diabetes and HIV/AIDS. He is also the holder of a number of patents based on the areas of his research in chronic diseases. Along with Drs. West and Lockhart, Dr. Lowe developed the first commercial product from Ganja for the treatment of Glaucoma.

Dr. Lowe has published over 20 books and has three in various stages of completion at this time. Dr. Lowe was the first Caribbean person to publish a science textbook series for secondary schools, which were not only used in Jamaica and the Caribbean but also in Africa. Some of his more recent publications include “Caribbean Herbs for Diabetes Management: Fact or Fiction?”, “Discovering the Future - The Emergence, Development and Future of Science and Technology in Jamaica”, and “Jamaica’s Ethnomedicine – Its Potential in the Healthcare System”. He has also published over 100 articles in the areas of science, technology and the health sciences for referred journals and the popular press.

Dr. Lowe holds many awards and accolades, including the Jamaica Observer Business Leader Award (2006) and the CCRP Living Legend Award (2012); and is the only Jamaican who is a member of the prestigious American Association for Cancer Research (AACR). Dr. Lowe is a member of the American Association for the Advancement of Science, A Fellow of the Royal Society of Medicine United Kingdom, Harvard Medical School Postgraduate Association, American Association of Pharmaceutical Scientists and the American Chemical Society and a Life Member of the New York Academy of Sciences.

Dr. Lowe is an Adjunct Professor in the Department of Medicine, University of Maryland School of Medicine, USA and Distinguished Adjunct Professor of Ethno-medicinal Chemistry, University of Technology, Jamaica.

Formal Education:

1956, Kingston, Jamaica – Calabar High School, Cambridge University School Certificate

1958, Kingston, Jamaica – Excelsior College, Cambridge Higher Schools Certificate (Distinction)

1961, Kingston, Jamaica – London University/University College of the West Indies, BSc. (Hons.), Natural Sciences

1970, Sydney, Australia – University of Sydney, MSc, Medicinal/Pharmaceutical Chemistry

1976, Manchester, England – Manchester University, PhD, Medicinal Chemistry
.

Professional Societies/Memberships:

1966- Present          (Hon) Member, Pharmaceutical Society of Jamaica

1967-1969                Member of the Australian & New Zealand Academy of Sciences (ANZAS), Australia

1964-1980                Chairman/Member, Science Teacher Association, Caribbean

1972-present            Jamaica Teachers Association, Jamaica

1974-2002                Associate of the Royal Institute of Chemistry, United Kingdom

1979-1986                Vice Chairman/Member, National Energy Commission, Jamaica

1981-1985                President, Jamaica Society of Scientists and Technologists, Jamaica

1986-present            Member, American Association for the Advancement of Science

1986-present            Life Member, New York Academy of Sciences, USA

1988-present            Member, American Association for the Advancement of Science (AAAS)

1994-present            Jamaica Institute of Management, Jamaica

2000-present            Member, Caribbean Academy of Sciences, Trinidad & Tobago

2000-present            Member, Caribbean Association for Herbal Research

2004-present            Member, World Future Society, USA

2006-present            Fellow, Royal Society of Medicine UK (Medicinal Chemistry Section), England

2007-present            Postgraduate Association, Harvard Medical School, Harvard University, USA

2007-present            American Association of Pharmaceutical Scientists (AAPS), USA

2008-present            Member, American Chemical Society (ACS), USA

2011-present            Member, American Association for Cancer Research (AACR), USA

2013 -present            Committee Member, Caribbean Export Development  Agency, CARIFORUM Region

2014-present            Member, Institute of Human Virology (IHV) Advisory Board, University of Maryland, USA


Publications:

Lowe H.I.C, (January 1968).  Isolation Characterization and Biological Activities of Metabolites of a Cylindrocarpon Species.  Australian & New Zealand Association for the Advancement of Science (A.N.Z.A.A.S) Congress, Christchruch, New Zealand

Coombs, Lowe, H., Watson (1972).  Chromone and Naphthoquinone Metabolites from a Cylindrocarpon Species. Australian Journal of Chemistry, 25, 875-9

Lowe HIC. Jamaican folk medicine. Jamaica Journal 1972; 6: 20–4.

Lockhart, A.B., Lowe, H., West, M., (1977).  The potential use of cannabis sativa in Ophthalmology. West Indian Medical Journal, XXVI, 66.

Lowe HIC. From folklore to super-medicine: periwinkle. Jamaica Journal 1977; 11: 46–8.

Lowe, H., (1979). Investigation of the Hypoglycaemic effects of Eryngium foetidium. 1st Annual Pharmaceutical/Medicinal Conference. College of Arts, Science and Technology (CAST), Jamaica.

Morrison, E.Y. St. A., Lowe, H., (1995).  Overview for Workshop on Diabetes Peculiar to Tropics:  International Workshop on Types of Diabetes Peculiar to Tropics, Cuttack, India, October 17-19, p. 314

Lowe H, Mansingh A. Jamaica’s Ethnomedicine: Its potential in the health care system. Proc. International Symposium. “Utilization of natural products in developing countries: trends and needs”, Natural Products Institute, July 10-14, UWI, Mona, Kingston. 2001: 47–52.

Lowe. H., E.Y. St. A. Morrison, (2002).  Hypoglycaemic effects of some Jamaican Plants, 2nd International Conference on Natural Products, National University of Singapore, July1-4, p 50.

Lowe, H., Smith, R., Campbell, N., Morrison, E.Y. St. A., (2002)  Lead Pollution and Amelioration Measures in the Community of Frazers Content, St. Catherine, Jamaica, WI Med. J., 51, No 3, p 160-163

Mansingh, A., Young, R., Yee, T., Delgoda, R., Robinson, D.W., Morrison, E.Y. St. A., Lowe, H., eds., (2002), Utilization of Natural Products in Developing Countries: Trends and Needs – University Printery, UWI, Mona, Kingston 7, Jamaica

Lowe, H., Wilkins, N., Morrison, E.Y. St. A., (2003).  Whither Medical Marijuana, WI. Med. J. 52, (1), 49-51.

Lowe, H., (2003).  Evaluation of the Bioactivity of two Psychotria Spp. Bi-Annual Conference of Caribbean Biomedical & Pharmaceutical Researchers, St Kitts.

Lowe, H.  (2003) Developing an Export Herb Industry-The Jamaican Model: A Viable & Sustainable Means of Development.  In: “Advancing Caribbean Herbs in the 21st Century –Proceedings of the Sixth International Workshop on Herbal Medicine in the Caribbean” Clement, Y.N. ed. The Caribbean Association of Researchers and Herbal Practitioners (CARAPA) & IICA on June 27-29, 2003 at the University of the West Indies, St. Augustine, Trinidad & Tobago.  Pg. 14-17.

Lowe, H. I. C. (2006).  The Importance of Standardizing our Caribbean Herbal Industry.  The Caribbean Pharmacist. 66 (1): 18-20.

Oladeinde, F., Lowe, H., Thomas, O., Bryant, J., Natural Plant Extracts for Anti-Tumor, Anti-HIV/Aids and As Adjuvant, 2nd    Morgan State University International Complementary and Alternative Medicine  Conference, May 26, 2006.

Oladeinde, F., Lowe, H., Bryant, J. Screening of Natural Plant Extracts For Anti-Tumor Properties against Aids-Associated and Non-Aids Associated CancersAnnals of Oncology 2008, Volume 19, Supplement 3.

Lowe, H., Bahado-Singh, P., Wheatley, A., Asemota, H., (2010).  The impact of bioactive principles from Ball Moss (Tillandsia recurvata sp.) on diabetes.  16th Annual InternationalUniversity Diabetes Outreach Programme, March 25 – 28, 2010, St. Ann, Jamaica.

Gardner, N.S., Wheatley, A.O., Bahado-Singh, P.S., McGrowder, D., De La Haye, W., Lowe, H., Salako, A., Morrison, E.Y.St.A,  and Asemota, H.N. (2008) Nutritional supplements in the treatment (secondary prevention) of alcohol and illicit drug dependence: mechanism of action in animal models.  Proceedings of the UWI Faculty of Pure and Applied Sciences Eighth Conference – February 26-28.

P.S. Bahado-Singh, A.O. Wheatley, H. Lowe, J. Bryant, H. N. Asemota, and  E.Y. St. A Morrison (2010) Marijuana, Smoking and Diabetes          . Proceedings of the UWI Diabetes Outreach Project (UDOP) 16th International Conference, Ocho Rios, Jamaica – March 25-28.  West Indian Med J 2010; 59 (Suppl. 1): 34.

H. Lowe, P.S. Bahado-Singh, A.O. Wheatley, H.N. Asemota, J. Bryant and E.Y. St. A Morrison (2010). The impact of bioactive principles from Ball Moss (Tillandsia recurvata sp.) on diabetes. Proceedings of the UWI Diabetes Outreach Project (UDOP) 16th International Conference, Ocho Rios, Jamaica – March 25-28.  West Indian Med J 2010; 59 (Suppl. 1): 34.

De La Haye, W.G., Gardner, Luke, K.J., N.S., Wheatley, A.O., Bahado-Singh, P.S., Lowe, H., Ahmad, M.H., Salako, A., Asemota, H.N. (2010)The use of Nutritional Supplements in Reducing Craving Associate with Cocaine Dependence.  2nd International Conference on Drug Discovery & Therapy, Dubai, United Arab Emirates-February 1-4, 2010.

Bahado-Singh, P., Riley, C., Wheatley A.O., Lowe, H., (2011) Relationship betweenprocessing method and the glycemic indices of ten sweet potato (Ipomoea batatas) cultivars commonly consumed in Jamaica. Journal of Nutrition and Metabolism Volume 2011 (2011), Article ID 584832.

Lowe, H., Watson C, Badal S, Ateh E., Toyang N., Bryant J., Anti-angiogenic properties of the Jamaica Ball Moss (Tillandsia recurvata L.). International Research Journal of Biological Sciences – August 2012, Vol. 1(4), 73-76.

Lowe, H., Watson C., Badal S., Toyang N., Bryant J., Isolation, purification and partial characterization of a glycoside from the Jamaican ball moss plant (Tillandsia recurvata L.) – Advances in Biological Chemistry, August 2012, 2, 274-282

Lowe, H., Watson C., Badal S., Peart P., Toyang N., Bryant J., Cytotoxic effect of Jamaican bissy nut extracts on various cancer cell lines.  Trade Science Inc., ACB, 1 (1), 2012 [47-49]

Lowe, H., Watson C., Badal S., Toyang N., Bryant J., Cycloartane -3, 24, 25-triol inhibits MRCKa kinase and demonstrates promising anti-prostate cancer activity in vitro.  Cancer Cell International 2012, 12:46.

Lowe, H., Watson C., Badal S., Toyang N., Bryant J. Kinase Inhibition by the Jamaican Ball Moss, Tillandsia recurvata L. Anticancer Research, 2012, 32, 4419-4422

Lowe, H.I.C., Watson, C.T., Badal, S., Ateh, E.N.,Toyang, N.J., Bryant, J. Anti-angiogenic properties of the Jamaican ball moss,(Tillandsia recurvata L.). International Research Journal of Biological Sciences, Vol. 1(4), 73-76, August (2012)

Lowe H.I.C., Watson, C.T. Badal, S., Toyang, N.J., Bryant, J. Cycloartane-3,24,25-triol inhibits MRCKα kinase and demonstrates promising anti prostate cancer activity in vitro. Cancer Cell International, November 14, 2012

Lowe H.I.C., Watson, C.T., Badal, S., Toyang, N.J., Bryant, J. Cytotoxic effect of Jamaican bissy nut extracts on various cancer cell lines. Applied Cell Biology, 2012,1 (1),  47-49.

Lowe H.I.C., Watson, C.T., Badal, S., Toyang, N.J., Bryant, J. Cycloartanes from the Jamaican Ball Moss (Tillandsia recurvata L.), Analytical Chemistry, 2013, 12, 5.

Lowe H.I.C., Toyang, N.J., Watson, C.T., Badal, S., Bahado-Singh, P., Bryant, J. In Vitro Anticancer activity of the crude extract and two Dicinnamate Isolates from the Jamaican Ball Moss (Tillandsia recurvata L.), American International Journal of Contemporary Research, 2013, 3 (1), 93-96.

Lowe H.I.C., Toyang, N.J., Bryant, J. In vitro and In vivo anticancer effects Tillandsia recurvata (Ball moss) from Jamaica. West Indian Medical Journal 2013; 62(3):177.

Lowe H.I.C., Toyang, N.J., Watson, C.T., Bryant, J.. The Anti-Cancerous Activity of Vernonia divaricata against Leukemia, Breast and Prostate Cancer in-vitro. West Indian Medical Journal 2013; 2013-232.

Lowe H.I.C., Bryant J. A case study of indigenous medicinal plants: Antioxidants properties, traditional uses and conservation strategies. In: Pereira D.A.M (2013). Medicinal plants: Antioxidants properties, traditional uses and conservation strategies. Nova Science Publishers Inc. NY. PP 259-266, 2013.

Lowe, H.I.C., Toyang, N.J., Watson, C.T., Bryant, J. Cycloartanes as Inhibitors of MRCKα and MRCKβ kinases. British Journal of Medicine and Medical Research; 4(9): 1802-181, (2014).

Lowe, H.I.C., Toyang, N.J., Heredia, A., Watson, C.T., Bryant, J. Anti HIV-1 activity of the crude extracts of Guaiacum officinale L. (Zygophyllaceae). European Journal of Medicinal Plants. 4(4): 483-489, (2014).

Lowe H.I.C, Toyang, N.J.,  Watson, C.T.,  Ayeah, K.N.N. Bryant, J. Antileukemic Activity of Tillandsia recurvata and Some of its Cycloartanes.  Anticancer Research. 34:3505-3510 (2014). Lowe H.I.C, Toyang, Watson, C.T., Bryant, J. Synthesis of Substituted 1,3-Diesters of Glycerol Using Wittig Chemistry.  Natural Product Communications, Vol 9, No.0, 1-3 (2014).