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Garry S A Myers

Garry S A Myers Ph.D.

Academic Title: Adjunct Assistant Professor
Primary Appointment: Microbiology and Immunology
Location: HSF2, S-449
Phone: (410) 706-5678
Fax: (410) 706-1482

Personal History:

1992 - B.Sc. (Hons) , U. Qld/NTU, Australia

1998 - Ph.D., U. Syd., Australia

After completing my PhD in 1998 on aspects of chlamydial virulence proteins, I joined the Australian Genome Research Facility, Melbourne Australia as a Research Officer, establishing the Microarray Group there. In 2002 I joined The Institute for Genomic Research (TIGR) as a postdoctoral fellow and was actively involved in several microbial genome projects. After joining the TIGR Faculty, I focused my work onto the genomics of the Order Chlamydiales and other intracellular bacterial pathogens. I joined the Department of Microbiology and Immunology in 2007 as part of the new Institute for Genome Sciences.

Research Interests:

I apply the tools of genomics, comparative genomics and functional genomics to understand bacterial diversity, virulence and host-pathogen interactions, specifically to intracellular bacteria such as Chlamydia.


Selected Recent Publications

Laroucau, K., Thierry S., Vorimore F., Blanco K., Kaleta E., Hoop R., Magnino S., Vanrompay D., Sachse K., Myers G. S. A., Bavoil P.M., Vergnaud G., and Pourcel C. (2008) High resolution typing of Chlamydophila psittaci by multilocus VNTR analysis (MLVA). Infect Genet Evol 8:171-81.  [PubMed]

Peters J, Wilson D. P., Myers G. S., Timms P., Bavoil P. M. (2007). Type III secretion a la Chlamydia. Trends in Microbiology. 15(6):241-51  [PubMed]

Myers G. S. A., Parker D., Al-Hasani K., Kennan R. M., Seemann T., Ren Q., Badger J. H., Selengut J.D., DeBoy R.T., Tettelin H., Boyce J.D., McCarl V.P., Han X., Nelson W.C., Madupu R., Mohamoud Y., Holley T., Fedorova N., Khouri H., Bottomley S.P., Whittington R.J., Adler B., Songer J.G., Rood J.I. and Paulsen I.T. (2007). The diminutive yet versatile genome of the animal pathogen, Dichelobacter nodosus. Nature Biotechnology. 29 April 2007; doi:10.1038/nbt1302 [PubMed]

Liu Z., Rank R., Kaltenboeck B., Magnino S., Dean D., Burall L., Plaut R.D., Read T.D., Myers G. S. A. and Bavoil P.M. (2007) Genomic Plasticity of the Rrn-Nqrf Intergenic Segment in the Chlamydiaceae. Journal of Bacteriology. 189(5):2128-32  [PubMed]

Myers G. S. A., Rasko D. A., Cheung J. K., Ravel J., Seshadri R., DeBoy R.T., Ren Q., Varga J., Awad M. M., Brinkac L. M., Daugherty S. C., Haft D.H., Dodson R. J., Madupu R., Nelson W.C., Rosovitz M. J., Sullivan S. A., Khouri H., Dimitrov G. I., Watkins K. L., Mulligan S., Benton J., Radune D., Fisher D. J., Atkins H.S., Hiscox T., Jost B. H., Billington S. J., Songer J. G., McClane B. A., Titball R. W., Rood J. I., Melville S. B., and Paulsen I. T. (2006) Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Research 16: 1031-1040.  [PubMed]

Palenik B., Ren Q., Dupont C.L., Myers G. S. A., Heidelberg J. F., Badger J. H., Madupu R., Nelson W. C., Brinkac L. M., Dodson R. J., Durkin A. S., Daugherty S. C., Sullivan S. A., Khouri H., Mohamoud Y., Halpin R., and Paulsen I.T. (2006) Genome sequence of Synechococcus CC9311: Insights into adaptation to a coastal environment. Proc Natl Acad Sci U S A 103: 13555-13559.  [PubMed]

Parker D., Kennan R. M., Myers G. S. A., Paulsen I. T., Songer J. G., and Rood J. I.. (2006) Regulation of type IV fimbrial biogenesis in Dichelobacter nodosus. Journal of Bacteriology 188: 4801-4811. [PubMed]

Ding X.Z., Paulsen I.T., Bhattacharjee A.K., Nikolich M.P., Myers G. S. A., and Hoover D.L. (2006) A high efficiency cloning and expression system for proteomic analysis. Proteomics 6: 4038-4046. [PubMed]

Rasko D.A., Myers G. S. A., and Ravel J. 2005. Visualization of comparative genomic analyses by BLAST score ratio. BMC Bioinformatics 6: 2.  [PubMed]

Paulsen I. T., Press C. M., Ravel J., Kobayashi D. Y., Myers G. S. A., Mavrodi D. V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R. J., Durkin A. S., Brinkac L. M., Daugherty S. C., Sullivan S. A., Rosovitz M. J., Gwinn M. L., Zhou L., Schneider D. J., Cartinhour S. W., Nelson W. C., Weidman J., Watkins K., Tran K., Khouri H., Pierson E. A., Pierson L. S.., Thomashow L. S., and Loper J.E. (2005) Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5. Nature Biotechnology 23: 873-878.  [PubMed]

Parker D., Kennan R. M., Myers G. S. A., Paulsen I. T., and Rood J. I. (2005) Identification of a Dichelobacter nodosus ferric uptake regulator and determination of its regulatory targets. Journal of Bacteriology 187: 366-375.  [PubMed]

Ding X. Z., Bhattacharjee A., Nikolich M. P., Paulsen I. T., Myers G. S. A., Seshadri R., and Hoover D.L. (2005) Cloning, expression, and purification of Brucella suis outer membrane proteins. Protein Expr Purif 40: 134-141.  [PubMed]

Seshadri R., Myers G. S. A., Tettelin H., Eisen J. A., Heidelberg J. F., Dodson R. J., Davidsen T. M., DeBoy R. T., Fouts D. E., Haft D. H., Selengut J., Ren Q., Brinkac L. M., Madupu R., Kolonay J., Durkin S. A., Daugherty S. C., Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J., Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S., Amin A., Vashisth P., McNeill T. Z., Xiang Q., Sodergren E., Baca E., Weinstock G. M., Norris S. J., Fraser C. M., and Paulsen I. T. (2004) Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes. Proc Natl Acad Sci U S A 101: 5646-5651. [PubMed]

Myers G. S. A. and Fraser C. M.. (2004) Non-pathogenic bacteria take center stage: a lesson in contrasts. Trends in Microbiology 12: 303-305. [PubMed]

Read T.D., Myers G. S. A., Brunham R. C., Nelson W. C., Paulsen I. T., Heidelberg J., Holtzapple E., Khouri H., Federova N.B., Carty H.A., Umayam L.A., Haft D. H., Peterson J., Beanan M. J., White O., Salzberg S. L., Hsia R. C., McClarty G., Rank R. G., Bavoil P. M., and Fraser C. M.. (2003) Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae. Nucleic Acids Res 31: 2134-2147. [PubMed]

Paulsen I. T., Banerjei L., Myers G. S. A., Nelson K.E., Seshadri R., Read T. D., Fouts D. E., Eisen J. A., Gill S. R., Heidelberg J. F., Tettelin H., Dodson R. J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R. T., Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B., Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D., Ketchum K. A., Dougherty B. A., and Fraser C. M. (2003) Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis. Science 299: 2071-2074. [PubMed]