Department of Epidemiology and Preventive Medicine (DEPM)

Denise L. Orwig, PhD

orwigAssistant Professor
Division of Gerontology

Howard Hall, Rm 203
660 W. Redwood St.
Baltimore, MD 21201
Phone: (410)410-706-8951
Fax: (410)410-706-4433
Email: dorwig@epi.umaryland.edu

Education

  • Ph.D. - The Pennsylvania State University, Biobehavioral Health (Minor: Gerontology), University Park, Pennsylvania. 1994-1998.
  • M.S. - The Johns Hopkins University, Applied Behavioral Science, Baltimore, Maryland, 1990-1993.
  • B.S. - University of Pittsburgh, Psychology/Business Dual Degree, Pittsburgh, Pennsylvania 1985-1989.

Memberships

  • American Association for Bone and Mineral Research
  • Maryland Gerontological Association
  • European Association for Clinical Pharmacology and Therapeutics
  • European Drug Utilization Research Group
  • National Osteoporosis Foundation
  • Sigma Phi Omega
  • The Gerontological Society of America
  • American College of Epidemiology
  • International Society of Pharmacoepidemiology

Honors & Awards

  • Recipient of the 2004 Penn State Alumni Emerging Professional Graduate Degree Award.  College of Health and Human Development, The Pennsylvania State University, 2004.
  • Poster Finalist Award at the Annual Scientific Meeting of the International Society of Pharmacoeconomics and Outcomes Research, Hamburg, Germany, 2004.
  • National Institutes of Health Extramural Loan Repayment Program Award through the National Center on Minority Health and Health Disparities. Title of project: Minority Health and Aging Development Project, 2002-2006.
  • National Research Service Award (NRSA) Postdoctoral Traineeship in the Primary Care Training Program, 2000-present.
  • Paper selected as best submission to the conference and presented as a highlighted talk at the joint conference of the European Association for Clinical Pharmacology and Therapeutics (EACPT) and the European Drug Utilization Research Group (EURODURG), Jerusalem, 1999.
  • National Institute on Aging Predoctoral Fellowship in Adult Development and Aging. Interdisciplinary Training in Gerontology, 1997-1998.

Patents, Inventions & Copyrights

  • Trademark for the MedMaIDE (76/423,110). An instrument for people with no medical background to assess medication management deficiencies in the elderly. 2002.
  • Copyright of the Medication Management Instrument for Deficiencies in the Elderly (MedMaIDE) and the MedMaIDE User’s Manual (Txu1-038-253), 2002.

National Service - Miscellaneous

  • Serve as a mentor for the Women’s Leadership Initiative in the College of Health and Human Development at the Pennsylvania State University, University Park, PA, 2004-present.
  • Member of Scientific Program Committee for Annual Meeting of the International Society of Pharmacoepidemiology, 2003-present.
  • Serve on a national committee to test a software program (Stop Osteoporosis) designed to assist clinicians in tracking fracture patients and obtaining critical data required for the management of these patients in order to improve osteoporosis treatment and prevent future bone loss and fracture, 2002-present.
  • Member of the Behavioral Change Consortium (BCC) established by the National Institutes of Health and the American Heart Association. Purpose to provide infrastructure to foster collaboration among 15 projects funded under an RFA calling for proposals to test innovative approaches to health behavior change, 2000-present.
  • Member of the Treatment Fidelity Workgroup. Implemented as part of the BCC to advance the definition, methodology and measurement of treatment fidelity both within the BCC and for the field of health behavior change, 2000-present.

Publications

  • Resnick, B., Orwig, D., Wehren, L., Zimmerman, S., Simpson, M., Magaziner, J. The Exercise Plus Program for older women post hip fracture: Participant perspectives. The Gerontologist, 45 (4): 539-544 (2005).
  • Wehren, L., Hawkes, W.G., Hebel, J.R., Orwig, D.L., Magaziner, J. Bone mineral density, soft tissue body composition, strength, and functioning after hip fracture. Journal of Gerontology: Medical Sciences, 60A (1): 80-84 (2005).
  • Resnick, B., Bellg, B., Borrelli, B., DeFrancesco, C., Breger, R., Hecht, J., Sharp, D., Levesque, C., Orwig, D., Ernst, D., Ogedegbe, G., Czajkowski, S. Examples of implementation and evaluation of treatment fidelity in the BCC Studies: Where we are and where we need to go. Annals of Behavioral Medicine, 29 (suppl): 46-54 (2005).
  • Resnick, B., Inguito, P., Orwig, D., Yahiro, J., Hawkes, W., Werner, M., Zimmerman, S., Magaziner, J. Treatment fidelity in behavior change research: A case example. Nursing Research, 54 (2):139-143 (2005).
  • Resnick, B., Orwig, D., Wehren, L., Hawkes, W., Hebel, J.R., Fontaine, K., Zimmerman, S., Magaziner, J. Health-Related Quality of Life: Is it a good indicator of function post-THR? Rehabilitation Nursing, 30 (2): 46-67 (2005).
  • Bellg, A.J., Borrelli, B., Resnick, B., Hecht, J., Minicucci, D., Ory, M., Ogedegbe, G., Orwig, D., Ernst, D., Czajkowski, S. Enhancing Treatment Fidelity in Health Behavior Change Studies: Best Practices and Recommendations from the Behavior Change Consortium. Health Psychology, 23 (5): 443-456 (2004).
  • Briesacher, B., Kamal-Bahl, S., Hochberg, M., Orwig, D., Kahler, K.H. Three-tiered co-payment drug coverage and use of non-steroidal anti-inflammatory drugs. Archives of Internal Medicine, 164: 1679-1684 (2004).
  • Paulose-Ram, R., Jonas, B.S., Orwig, D., Safran, M. Prescription psychotropic medication use among the US adult population: Results from the third National Health and Nutrition Examination Survey (NHANESIII). Journal of Clinical Epidemiology, 57(3): 309-317 (2004).
  • Wehren, L., Hawkes, W., Orwig, D., Hebel, J.R., Zimmerman, S.I., and Magaziner, J. Gender differences in mortality following hip fracture. Journal of Bone and Mineral Research, 18(12): 2231-2237 (2003).
  • Wehren, L., Hawkes, W., Hebel, J.R., Orwig, D., Zimmerman, S.I., Fox, K.M., Yu-Yahiro, J., Magaziner, J.  Predictors of bone loss after hip fracture.  Osteoporosis International, 15: 125-131 (2003).
  • Magaziner, J., Fredman, L., Hawkes, W., Hebel, J.R., Zimmerman, S., Orwig, D.L., Wehren, L.  Changes in functional status attributable to hip fracture: A comparison of hip fracture patients to community-dwelling aged.  American Journal of Epidemiology, 157(11): 1023-1031 (2003).
  • Resnick, B., Wehren, L. Orwig, D., Magaziner, J. Testing the Reliability and Validity of the Self-Efficacy and Outcome Expectations for Osteoporosis Medication Adherence Scales. Orthopedic Nursing, 22(2): 139-147 (2003).
  • Resnick, B., Magaziner, J., Orwig, D., Zimmerman, S.I. Evaluating the components of the Exercise Plus Program: Rationale, theory, and implementation. Health Education Research, 17:648-658 (2002).
  • Resnick, B., Orwig, D., Magaziner, J., Wynne, C. The effect of social support on exercise behavior in older adults. Clinical Nursing Research 11(1): 52-70 (2002).
  • Resnick, B., Nahm, E., Orwig, D., Zimmerman, S.I., and Magaziner, J. Measurement of activity in older adults: Reliability and validity of the Step Activity Monitor. Journal of Nursing Measurement 9 (3): 275-290 (2001).
  • Resnick, B., Orwig, D., Zimmerman, S.I., Furstenberg, A-L., and Magaziner, J. Model testing for reliability and validity of the outcome expectations for exercise scale. Nursing Research 50(5): 293-299 (2001).
  • Resnick, B., Zimmerman, S.I., Orwig, D., Furstenberg, A-L., and Magaziner, J. Outcome expectations for exercise scale: utility and psychometrics. Journal of Gerontology: Social Sciences 55B (6): S352 (2000).
  • Dellasega, C., Orwig, D.L., Lenz, E. and Ahern, F.M. The post-discharge course of rural and urban elderly cardiac patients. Journal of Gerontology: Medical Sciences 54A(10): M514 (1999).

Publications – In Review

  • Ryder, P., Orwig, D., Magaziner, J. Post-operative interventions to improve functional recovery from hip fracture: When will we stop shooting from the hip? (under review)
    Streeten, E.A., Mohamed, A., Orwig, D., Sack, P. Shuldiner, A. Medical-Orthopedic team improves osteoporosis treatment of inpatient fracture patients. (under review)
  • Magaziner, J., Wehren, L., Hawkes, W.G., Orwig, D., Hebel, J.R., Fredman, L., Stone, K., Zimmerman, S., Hochberg, M. Excess loss in bone mineral density following hip fracture: Another significant consequence of a common geriatric problem. (under review)
  • Orwig, DL., Brandt, N., Gruber-Baldini, A. Testing the reliability and validity of a Medication Management Assessment Instrument for Community-Dwelling Elderly. (under review)
  • Safran, M., Paulose-Ram, R., Jonas, B.S., Gu, Q., Orwig, D. Prevalence and Trends in Psychotropic Medication Use Among US Adults, 1999-2000. (under review)

Current Grant Funding Received

  • Antioxidants and Functional Performance in Hip Fracture Patients (No number). G. Hicks (PI), Role on Project: Investigator, 7/1/05-6/30/06, $15,000, University of Maryland School of Medicine Intramural Grant.
  • Sequelae of Hip Fracture in Men: An Epidemiologic Study (R01 AG009901-10). J. Magaziner/M. Hochberg (PIs), Role on Project: Investigator, 3/15/05-2/28/10, $3,675,801, National Institute on Aging.
  • Task-Oriented Exercise and Robotics in Neurological Disease (Planning Grant and Core Services) (No number). R. Macko (PI), Role on Project: PI of Recruitment Core, 10/01/04—09/30/09, $10,600, Department of Veterans Affairs.
  • Use of Complimentary and Alternative Medicine in Older African Americans (No number). S. Black (PI), Role on Project: Co-PI, 06/01/04-05/31/05, $15,000, The Center for Integrative Medicine, University of Maryland School of Medicine.
  • Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Repair “FOCUS” (no number). J. Carson (PI), Role on Project: PI of Baltimore Clinical Center, 1/1/04-12/31/07, $378,000,  National Heart, Lung and Blood Institute.
  • Prevention of Pressure Ulcers in Hip Fracture Patients (R21 AG21618). M. Baumgarten (PI), Role on Project: Investigator, 09/30/03-08/31/06, $150,000, National Institute on Aging
  • Multinational, multicenter, double-blind, randomized, placebo-controlled, parallel group study assessing the efficacy of intravenous zoledronic acid in preventing subsequent osteoporotic fractures after a hip fracture (HORIZON-RFT) (no number). J. Magaziner/K. Lyles (PIs), Role on Project: PI of Baltimore Clinical Center, 04/1/04-03/31/08, $804,200, Novartis Pharmaceuticals Corporation.
  • Rehabilitation of Cognitively Impaired Hip Fracture Patients (no number). A. Gruber-Baldini (PI), Role on Project: Investigator, 09/01/02—08/31/04, $15,000, Women’s Health Research Group Grant Program, University of Maryland, Baltimore.
  • Prevention of Pressure Ulcers in Hip Fracture Patients (no number). M. Baumgarten (PI), Role on Project: Investigator, 7/01/02-6/30/03, $15,000 University of Maryland School of Medicine Intramural Grant.
  • Locus of Care & Pressure Ulcers in Hip Fracture Patients (R01 AR47711). M. Baumgarten (PI), Role on Project: Investigator, 9/30/01-08/31/06,  $3,262,048, National Institute on Aging.
  • Claude D. Pepper Older Americans Independence (P60 AG12583). A. Goldberg/J. Magaziner (PIs), Role on Project: Co-PI of Core A, 08/15/01-06/30/06, $7,125,443. National Institute on Aging.
  • Determinants of Recovery Following Hip Fracture (Bone Metabolism) (R01 AG18668). J. Magaziner /J. Yu-Yahiro (PIs), Role on Project: Investigator, 9/01/01-8/31/06, $2,278,816, National Institute on Aging.
  • Testing the Exercise Plus Program Following Hip Fracture (R01 AG17082). B. Resnick/ J. Magaziner (PIs), Role on Project: Investigator, 9/30/99-6/30/06, $2,108,342, National Institute on Aging. 
  • Determinants of Recovery from Hip Fracture (Bone/Muscle) (R37 AG09901). J. Magaziner (PI), 1999, Role on Project: Investigator, 7/1/92-6/30/03, $2,204,568, National Institute on Aging.
  • Research Training in the Epidemiology of Aging (T32 AG000262). J. Magaziner (PI), Role on Project: Faculty, 05/01/98-04/30/08, $1,028,450, National Institute on Aging.

Past Grant Funding Received

  • Resource Utilization in Paget’s Disease Patients (Task Order #6) (no number). Role on Project: PI, 2/01/04-1/30/05, $20,000, Novartis Pharmaceutical Corporation.
  • Assessing Treatment Fidelity in the Pepper Center: Enhancing Intervention Research (no number). Role on Project: PI, 05/01/03-04/30/04, $15,000, Intramural Grant Program from the Claude D. Pepper Center.
  • Timing and Intensity of Strengthening After Hip Fracture (R21 HD043269). R. Craik (PI), Role on Project: Consultant, 9/01/02- 8/31/04, National Institutes of Health.
  • What Effect do Tiered Drug Plans have on NSAID use (no number) B. Breisacher (PI), Role on Project: Investigator, 11/01/02- 12/31/03, $25,000, Novartis Pharmaceuticals Corporation.
  • Recovery After Hip Fracture: The LEGS Score (no number) J. Magaziner (PI), Role on Project: Investigator, 11/1/01- 6/1/03, $48,426, Bristol-Myers Squibb.
  • Improving Medication Compliance After Hospital Discharge in elderly patients using the MedMaIDE: A Pilot Study (no number). Role on Project: PI, 7/01/01-6/30/03, $12,000, MedStar Research Institute.
  • The Construct of Hip Fracture-Specific Functional Tests and Feasibility of a New Training Program (no number). G. Alon (PI), Role on Project: Co-Investigator, 6/1/02-5/31/03, $20,000, Intramural Grant Program from the Claude D. Pepper Center.
  • Assessing Nurse Practitioner Intervention on Bone-Strengthening Medication Prescriptions in Urban Elderly Women.  N. Brandt (PI), Role on Project: Investigator, 7/1/01-12/31/01, $5600, Geriatrics and Gerontology Education and Research Program (GGEAR).
  • Sharing the Burden: Identification and Prevention of Environmental/Occupational Health Risks for Women. E. Silbergeld (PI), Role on Project: Investigator, 9/01/01-12/31/04, $20,000, The Heinz Foundation.
  • Reliability and Validity Testing of a Medication Management Instrument for Older Adults (no number). Role on Project: PI, 3/1/00-2/28/02, $90,909. AARP Andrus Foundation.
  • Evaluation of a Medication Management Pilot Program among Elderly Living in Congregate Housing. A. Spellbring (PI), Role on Project: Co-Investigator, 7/1/99-12/31/00, $47,810. Geriatrics and Gerontology Education and Research Program (GGEAR).
  • Pressure Ulcers in Elderly Hip Surgery Patients: Feasibility Study (no number). M.Baumgarten (PI), Role on Project: Investigator, 7/01/99- 6/30/00, $15,000, University of Maryland School of Medicine Intramural Grant.
  • Longitudinal Use of Psychoactive Medications in Community Dwelling Elders. C. Dellasega (PI), Role on Project: Co-Investigator, 1/1/98-12/31/98, $20,000.  Nursing Research Program, Clinical Applications Research, Glaxo Wellcome, Inc.
  • Attribution of Stroke Risk in a Rural Community. Role on Project: PI, 7/1/97-12/31/97, $1500. Rural Nursing Centers Project Seed Grant, Pennsylvania.

Pending Grant Funding

  • Epidemiology of Bone Strength and Muscle Composition After Hip Fracture in Men (not yet assigned). J. Magaziner (PI), Role on Project: Investigator/ Project Director, 12/01/06-11/30/11, National Institute on Aging.
  • Pressure Ulcer Prevention in Elderly Hip Fracture Patients: A Randomized Trial (not yet assigned). M. Baumgarten (PI), Role on Project: Investigator, 12/01/06-11/30/11, National Institute on Aging.
  • Feasibility of a Theory-Based Online Hip Fracture Resource Center for Caregivers (not yet assigned). E-S. Nahm (PI), Role on Project: Investigator, 12/01/06-11/30/08, National Institutes of Health.
  • FOCUS Hip Fracture Transfusion Trial: Delirium and Other Cognitive Outcomes (R01 HL085706). A. Gruber-Baldini (PI), Role on Project: Investigator, 07/01/06-06/30/09, $1,991,493, National Institutes of Health.
  • Biological Pathways of Acute and Chronic Stress in Aged Hip Fracture Caregivers (not yet assigned). L. Fredman (PI), Role on Project: PI of Subcontract, 07/01/06-06/30/11, $1,845,938, National Institute on Aging.
  • Inflammatory Cytokines & Functional Decline Following Hospitalization in Elders (R21 AG028340). R. Miller (PI), Role on Project: Investigator, 07/01/06-06/30/07, $275,000, National Institutes on Aging.
  • Bilateral Arm Training in Sub-Acute Stroke (R01 HD050693). J. Whitall (PI), Role on Project: Investigator, 04/01/06-03/31/11, NICHD.
  • Effect of Hip Fracture on Innate Immunity (R21 AG027843). J. Powell (PI), Role on Project: Investigator, 04/01/06-3/31/08, National Institute on Aging.
  • Timing & Intensity of Lower Extremity Exercise after Hip Fracture (R01 HD052053). J. Magaziner (PI), Role on Project: PI Clinical Coordinating Center, 12/01/05-05/31/10, NICHD.
  • Increasing screening and treatment of osteoporosis in minority women (no number). C. Layson-Wolf (PI), Role on Project: Co-PI, 12/1/05-11/30/06, Proctor and Gamble Regional Grant-in-Aid.
  • Caregivers & Med Management in Elderly Post-Discharge (R01 AG026026). Role on Project: PI, 04/01/05—03/31/08, National Institute on Aging. 
  • A Longitudinal Study of Comorbid Depression and Diabetes (not yet assigned). S. Black (PI), Role on Project: Investigator, 07/01/04-06/30/09, National Institute on Diabetes, Digestive and Kidney Diseases.

 

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