The Center for Vaccine Development (CVD) has earned an international reputation for creating and testing vaccines against cholera, typhoid, malaria and other infectious diseases, including smallpox the West Nile virus and avian flu.
In addition to its research and outpatient facilities in Baltimore and College Park, Maryland, the CVD conducts clinical studies in Mali, West Africa; Malawi, Southern Africa; and in Santiago, Chile; among other sites. The Center’s international staff includes molecular biologists, immunologists, internists, pediatricians, epidemiologists, biostatisticians and entomologists. Myron M. Levine, M.D., D.T.P.H. has been Director of the CVD since its inception.
The CVD is engaged in the full range of vaccinology, from basic science through vaccine development, clinical evaluation and field studies. Mission priorities include:
Quantifying the relative importance of various pathogens through epidemiologic studies.
Identifying virulence properties through studies of molecular pathogenesis to construct vaccine candidates.
Assessing the suitability of candidate vaccines in clinical studies.
Measuring human immune responses to vaccines.
Evaluating the efficacy of candidate vaccines in large-scale field trials.
Advising governments and international agencies on vaccine policy.
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